Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christina Del Casale"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Programmed cell death regulates early development but how various factors (for example, TRADD, FADD and RIPKs) regulate this is unclear. Here, the authors show that a single allele of Tradd is essential for survival, when both Ripk3 and Ripk1 are kno
Externí odkaz:
https://doaj.org/article/87a04eb49a6d4286879173b72990596b
Autor:
Mark Mendonca, Hillary Millar Quinn, Brenda Salantes, Andriana Lebid, Katherine E. Santostefano, Christina Del Casale, Toshinobu Nishimura, Barry Morse, Marilda Beqiri, Luis Borges, Mark A. Wallet, Lucas Thompson, Sydney Bucher
Publikováno v:
Blood. 138:2771-2771
Introduction Allogenic CAR-T cell therapies for cancer provide a new option to reduce barriers faced by autologous cell therapies, but several challenges remain. One challenge is the risk of graft versus host disease (GvHD) caused by the infused T ce
Autor:
Luis J. Sigal, Eric B. Wong, Brian Montoya, Colby Stotesbury, Nicole A. Wilski, Christina Del Casale, Christopher M. Snyder
Publikováno v:
J Immunol
CMV has been proposed to play a role in cancer progression and invasiveness. However, CMV has been increasingly studied as a cancer vaccine vector, and multiple groups, including ours, have reported that the virus can drive antitumor immunity in cert
Autor:
Christina Del Casale, Timothy J. Purwin, Andrew E. Aplin, Nicole A. Wilski, Christopher M. Snyder
Publikováno v:
Journal of virology. 93(20)
Cytomegalovirus (CMV) is a ubiquitous β-herpesvirus that infects many different cell types. CMV has been found in several solid tumors and it has been hypothesized that it may promote cellular transformation or exacerbate tumor growth. Paradoxically
Autor:
Nicole A. Wilski, Andrew E. Aplin, Christopher M. Snyder, Vitali Alexeev, Constantine Daskalakis, Christina Del Casale, Timothy J. Purwin
Publikováno v:
Cancer Immunology Research. 8:A74-A74
Herpesvirus-based immunotherapies are emerging as exciting new possibilities for vaccines and cancer treatment. We have been exploring the use of a cytomegalovirus (CMV)-based cancer therapy to promote productive tumor-specific immunity and modify th