Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christina Cowan-Ellsberry"'
Autor:
Jon A. Arnot, Giulia Vilone, John N. Westgate, Sean M. Hays, Christina Cowan-Ellsberry, Lesa L. Aylward, Cian O’Mahony
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology
Exposure models provide critical information for risk assessment of personal care product ingredients, but there have been limited opportunities to compare exposure model predictions to observational exposure data. Urinary excretion data from a biomo
Autor:
David E. Powell, Jaeshin Kim, Christina Cowan-Ellsberry, Kent B. Woodburn, Gary E. Kozerski, Shihe Xu, Donald Mackay
Publikováno v:
Environmental Toxicology and Chemistry. 34:2689-2702
The environmental sources, fate, transport, and routes of exposure of decamethylcyclopentasiloxane (D5; CAS no. 541-02-6) are reviewed in the present study, with the objective of contributing to effective risk evaluation and assessment of this and re
Autor:
Lawrence P. Burkhard, Karen A. Kidd, Christina Cowan-Ellsberry, Michelle R. Embry, Robert A. Hoke
Publikováno v:
Integrated Environmental Assessment and Management. 8:13-16
Once they are released into the environment, a number of chemicals are known to bioaccumulate in organisms, sometimes to concentrations that may threaten the individual or their predators. However, use of physical or chemical properties or results fr
Publikováno v:
Regulatory Toxicology and Pharmacology. 55:321-329
The need to understand and estimate quantitatively the aggregate exposure to ingredients used broadly in a variety of product types continues to grow. Currently aggregate exposure is most commonly estimated by using a very simplistic approach of addi
Publikováno v:
Regulatory Toxicology and Pharmacology. 52:46-52
With the recent introduction of exposure-based Quantitative Risk Assessment (QRA) as an approach to the evaluation, of materials in finished consumer products that are potential dermal sensitizers, the need for robust exposure data was clearly identi
Autor:
Christina Cowan-Ellsberry, Susanne Demmerle, Jean-Pierre Cravedi, Scott D. Dyer, Mary Jo Bernhard, E. Perdu-Durand
Publikováno v:
Chemosphere. 72:850-862
Developing regulatory activities (e.g., REACh, [DGEE. 2003. Directorates General Enterprise and Environment. The new EU chemicals legislation REACH. DG Enterprise, Brussels, Belgium. (http://www.europa.eu.int/comm/enterprise/reach/index_en.htm)]) wil
Autor:
Scott D. Dyer, Kathleen Stanton, Darci Ferrer, Christina Cowan-Ellsberry, Philip B. Dorn, Donald J. Versteeg, Scott E. Belanger, Drew C. McAvoy, Hans Sanderson
Publikováno v:
Cowan-Ellsberry, C, Sanderson, H, Belanger, S, Dorn, P, Dyer, S, McAvoy, D, Versteeg, D, Ferrer, D & Stanton, K 2014, ' Environmental Safety of the Use of Major Surfactant Classes in North America ', Critical Reviews in Environmental Science & Technology, vol. 44, no. 17, pp. 1893-1993 . https://doi.org/10.1080/10739149.2013.803777
Critical Reviews in Environmental Science and Technology
Critical Reviews in Environmental Science and Technology
This paper brings together over 250 published and unpublished studies on the environmental properties, fate, and toxicity of the four major, high-volume surfactant classes and relevant feedstocks. The surfactants and feedstocks covered include alcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a6ee63643483f1cdc1446e6a3249a0
https://pure.au.dk/portal/da/publications/environmental-safety-of-the-use-of-major-surfactant-classes-in-north-america(0f7a0ae9-dc30-4a07-8a45-88cc0397c25e).html
https://pure.au.dk/portal/da/publications/environmental-safety-of-the-use-of-major-surfactant-classes-in-north-america(0f7a0ae9-dc30-4a07-8a45-88cc0397c25e).html
Autor:
John W. Nichols, Jon A. Arnot, Patrick N. Fitzsimmons, Duane B. Huggett, Christina Cowan-Ellsberry
Publikováno v:
Environmental Toxicology and Chemistry.
Models were developed to predict the bioconcentration of well-metabolized chemicals by rainbow trout. The models employ intrinsic clearance data from in vitro studies with liver S9 fractions or isolated hepatocytes to estimate a liver clearance rate,
Autor:
Gregg Hancock, Michelle R. Embry, Jeanne Y. Domoradzki, Irvin R. Schultz, Beate I. Escher, John W. Nichols, Dustin D. Holden, Rebecca Johnson, Marlies Halder, Patrick N. Fitzsimmons, Mary Jo Bernhard, James Hill, Curtis Eickhoff, Christina Cowan-Ellsberry, Sibylle Rutishauser, Adelbayo Adekola, Scott D. Dyer, Helmut Segner, Karla Johanning, Susan Erhardt
Publikováno v:
Current Protocols in Toxicology
Standard protocols are given for assessing metabolic stability in rainbow trout using the liver S9 fraction. These protocols describe the isolation of S9 fractions from trout livers, evaluation of metabolic stability using a substrate depletion appro
Autor:
Marlies Halder, Michelle R. Embry, Susan Erhardt, John W. Nichols, Scott D. Dyer, Christina Cowan-Ellsberry, Sibylle Rutishauser, Jung Hwan Kwon, Helmut Segner, Beate I. Escher, Karla Johanning, Mattheus T.T. Oosterwijk
Publikováno v:
Chemical research in toxicology. 24(7)
Binding of hydrophobic chemicals to colloids such as proteins or lipids is difficult to measure using classical microdialysis methods due to low aqueous concentrations, adsorption to dialysis membranes and test vessels, and slow kinetics of equilibra