Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christina Brachetti"'
Autor:
Marten A. Fischer, Al-Hassan M. Mustafa, Kristin Hausmann, Ramy Ashry, Anita G. Kansy, Magdalena C. Liebl, Christina Brachetti, Andrea Piée-Staffa, Matthes Zessin, Hany S. Ibrahim, Thomas G. Hofmann, Mike Schutkowski, Wolfgang Sippl, Oliver H. Krämer
Publikováno v:
Journal of Advanced Research, Vol 60, Iss , Pp 201-214 (2024)
Introduction: Posttranslational modification of proteins by reversible acetylation regulates key biological processes. Histone deacetylases (HDACs) catalyze protein deacetylation and are frequently dysregulated in tumors. This has spurred the develop
Externí odkaz:
https://doaj.org/article/0bdd50c9fd09429e928b1f2b75be1138
Autor:
Marten A. Fischer, Al-Hassan M. Mustafa, Kristin Hausmann, Ramy Ashry, Anita G. Kansy, Magdalena C. Liebl, Christina Brachetti, Andrea Piée-Staffa, Matthes Zessin, Hany S. Ibrahim, Thomas G. Hofmann, Mike Schutkowski, Wolfgang Sippl, Oliver H. Krämer
IntroductionPosttranslational modification of proteins by reversible acetylation regulates key biological processes. Histone deacetylases (HDACs) catalyze protein deacetylation and are frequently dysregulated in tumors. This has spurred the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a93a992bfae64cae79dafac24079711
https://doi.org/10.1101/2023.03.09.531973
https://doi.org/10.1101/2023.03.09.531973
Autor:
Nicole Kiweler, Helena Schwarz, Alexandra Nguyen, Stephanie Matschos, Christina Mullins, Andrea Piée-Staffa, Christina Brachetti, Wynand P. Roos, Günter Schneider, Michael Linnebacher, Walburgis Brenner, Oliver H. Krämer
Publikováno v:
Cell Biology and Toxicology.
The epigenetic modifier histone deacetylase-2 (HDAC2) is frequently dysregulated in colon cancer cells. Microsatellite instability (MSI), an unfaithful replication of DNA at nucleotide repeats, occurs in about 15% of human colon tumors. MSI promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d80641a9cd52eb5013613d283b881c
https://doi.org/10.1007/s10565-022-09731-3
https://doi.org/10.1007/s10565-022-09731-3
Autor:
Vanessa Wachholz, Teodora Nikolova, Siavosh Mahboobi, Mandy Beyer, Al-Hassan M. Mustafa, Andreas Sellmer, Melanie Dzulko, Walburgis Brenner, Thomas Kindler, Christina Brachetti, Oliver H. Krämer, Sven J. Henninger, Andrea Piee-Staffa, Patricia Haehnel, Yanira Zeyn
Publikováno v:
Archives of Toxicology
Acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase (FLT3) is a clinically unresolved problem. AML cells frequently have a dysregulated expression and activity of epigenetic modulators of the histone deacetylase (HDAC) family.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6e9c9334528e64c13e6fea58283b75