Výsledky vyhledávání - "Christina Bjenning"

Autor: George B, Stefano, Christina, Bjenning, Fuzhou, Wang, Nan, Wang, Richard M, Kream

Publikováno v: Advances in experimental medicine and biology. 982

Genetic polymorphisms, in concert with well-characterized etiology and progression of major pathologies, plays a significant role in aberrant processes afflicting human populations. Mitochondrial heteroplasmy represents a dynamically determined co-ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9dd228ff7be8631fe34b1d2985c2685e
https://pubmed.ncbi.nlm.nih.gov/28551808

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Mitochondrial Heteroplasmy

Autor: George B. Stefano, Christina Bjenning, Fuzhou Wang, Nan Wang, Richard M. Kream

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9783319553290

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29690777117e056c9b879aa178132a96
https://doi.org/10.1007/978-3-319-55330-6_30

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Isolation and characterization of a leech neuropeptide in rat brains: coupling to nitric oxide release in leech, rat and human tissues

Autor: Beatrice Salzet, Michel Salzet, Thomas V. Bilfinger, Jean-Claude Beauvillain, Jean Lesage, George B. Stefano, Christos M. Rialas, Pierre Sautière, Christina Bjenning

Publikováno v: Molecular Brain Research. 55:173-179

The osmoregulator peptide (leech osmoregulatory factor, LORF; IPEPYVWD) was first found in the leech central nervous system (CNS). Given the fact that certain peptides can be found in mammals and invertebrates, e.g., opioid, we examined rat brains to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d338ab1e15c6ed45724a90ceaa479f4d
https://doi.org/10.1016/s0169-328x(97)00156-3

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Tachykinins with unusual structural features from a urodele, the amphiuma, an elasmobranch, the hammerhead shark, and an agnathan, the river lamprey

Autor: Christina Bjenning, Yurii Rusakov, Vera M. Bondareva, David Waugh, Per Franklin Nielsen, J. Michael Conlon

Publikováno v: Peptides. 16:615-621

Tachykinins were purified from extracts of gastrointestinal tissues of the urodele, Amphiuma tridactylum (three-toed amphiuma), and the elasmobranch Sphyrna lewini (hammerhead shark), and from the brain of the agnathan Lampetra fluviatilis (river lam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb5e729d3a962bb7792b1235c1c491b
https://doi.org/10.1016/0196-9781(95)00010-h

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Structural characterization of neuropeptide Y from the brain of the dogfish, Scyliorhinus canicula

Autor: Christina Bjenning, Neil Hazon, J. Michael Conlon

Publikováno v: Peptides. 13:493-497

A peptide of the pancreatic polypeptide (PP) family was isolated in pure form from the brain of an elasmobranch fish, Scyliorhinus canicula (European common dogfish). The primary structure of the peptide was established as: Tyr-Pro-Ser-Lys-Pro-Asp-As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1285c61142e6aeb77e2082e0ea7a918a
https://doi.org/10.1016/0196-9781(92)90080-m

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Bombesin-like immunoreactivity in skates and the in vitro effect of bombesin on coronary vessels from the longnose skate, Raja rhina

Autor: Susanne Holmgren, Christina Bjenning, Anthony P. Farrell

Publikováno v: Regulatory Peptides. 35:207-219

Bombesin-like immunoreactivity is present in nerve fibers projecting to the cardiovascular system, including the coronary arteries, and to the gastrointestinal canal, and in endocrine cells of the gut of skates belonging to the family Rajidae. Synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2a2392ab4ca42c5eaff9e7d12927e6
https://doi.org/10.1016/0167-0115(91)90084-t

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Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity

Publikováno v: Journal of medicinal chemistry. 51(2)

The synthesis and SAR of a novel 3-benzazepine series of 5-HT2C agonists is described. Compound 7d (lorcaserin, APD356) was identified as one of the more potent and selective compounds in vitro (pEC50 values in functional assays measuring [(3)H]phosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023ac9ea3dfbee3121f4be18befd7671
https://pubmed.ncbi.nlm.nih.gov/18095642

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G protein-coupled receptors as therapeutic targets for obesity and type 2 diabetes

Autor: Christina, Bjenning, Hussien, Al-Shamma, William, Thomsen, Jim, Leonard, Dominic, Behan

Publikováno v: Current opinion in investigational drugs (London, England : 2000). 5(10)

The prevalence of obesity and type 2 diabetes, two strongly correlated disorders, is increasing worldwide. Weight loss can reduce the risk of developing type 2 diabetes and the pharmacological treatments normally required to manage this disorder. Eve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d713ae0e95826d7d3dac2fed5834968e
https://pubmed.ncbi.nlm.nih.gov/15535426

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Novel tachykinins from the brain of the sea lamprey, Petromyzon marinus, and the skate, Raja rhina

Autor: Christina Bjenning, Stacia A. Sower, David Waugh, J M Conlon

Publikováno v: Peptides. 15(1)

Using radioimmunoassays for mammalian tachykinins, peptides with substance P-like immunoreactivity and neurokinin A-like immunoreactivity were identified in an extract of the brain of the longnose skate, Raja rhina (elasmobranch) but only a peptide w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba6ea8884eb9ca6a5740de082865b71
https://pubmed.ncbi.nlm.nih.gov/8015973

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