Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christina Benda"'
Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming
Autor:
Zhiwei Luo, Xiaobing Qing, Christina Benda, Zhijian Huang, Meng Zhang, Yinghua Huang, Hui Zhang, Lulu Wang, Yiwei Lai, Carl Ward, Giacomo Volpe, Xiaofen Zhong, Baoming Qin, Qiang Zhuang, Miguel A. Esteban, Wenjuan Li
Publikováno v:
Cell Regeneration, Vol 8, Iss 1, Pp 21-29 (2019)
Class IIa histone deacetylases (HDACs) are a subfamily of HDACs with important functions in development and adult tissue homeostasis. As opposed to other HDACs, they lack catalytic function and bind transcription factors to recruit transcriptional co
Externí odkaz:
https://doaj.org/article/294dc3b4102440d68e26f5380b6dcd97
Autor:
Eva Harreither, Hanna A Rydberg, Helene L Åmand, Vaibhav Jadhav, Lukas Fliedl, Christina Benda, Miguel A Esteban, Duanqing Pei, Nicole Borth, Regina Grillari-Voglauer, Oliver Hommerding, Frank Edenhofer, Bengt Nordén, Johannes Grillari
Publikováno v:
Cell Regeneration, Vol 3, Iss 1 (2014)
Background: Oct4 is a transcription factor that plays a major role for the preservation of the pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic cells to induced pluripotent stem cells (iPSC) or other progeni
Externí odkaz:
https://doaj.org/article/caf0eccf17364ce998754428eaf05894
Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming
Autor:
Qiang Zhuang, Yiwei Lai, Hui Zhang, Lulu Wang, Baoming Qin, Xiaofen Zhong, Miguel A. Esteban, Giacomo Volpe, Wenjuan Li, Christina Benda, Zhiwei Luo, Meng Zhang, Xiaobing Qing, Zhijian Huang, Yinghua Huang, Carl Ward
Publikováno v:
Cell Regeneration, Vol 8, Iss 1, Pp 21-29 (2019)
Class IIa histone deacetylases (HDACs) are a subfamily of HDACs with important functions in development and adult tissue homeostasis. As opposed to other HDACs, they lack catalytic function and bind transcription factors to recruit transcriptional co
Autor:
Christina Benda, David P. Ibañez, Zhongzhou Yang, Qiang Zhuang, Micky D. Tortorella, Mazid Md. Abdul, Jiayu Chen, Andrew P. Hutchins, Meng Zhang, Jianguo Zhou, Yan Xu, Xichen Bao, Hui Zhang, Shaorong Gao, Yinghua Huang, Baoming Qin, Zhijian Huang, Jiayin Yang, Xiuling Fu, Ping Liu, Yulin Liu, Xiangpeng Guo, Bushra Mirza, Wenjuan Li, Xiaofen Zhong, Carl Ward, Tanveer Ahmed, Zhiwei Luo, Shahzina Kanwal, Wenxia Fan, Xihua Zhu, Miguel A. Esteban, Muhammad Jadoon Khan, Hung-Fat Tse, Dehao Huang
Publikováno v:
Nature Cell Biology. 20:400-412
Somatic cell reprogramming by exogenous factors requires cooperation with transcriptional co-activators and co-repressors to effectively remodel the epigenetic environment. How this interplay is regulated remains poorly understood. Here, we demonstra
Autor:
Baojian Liao, Duanqing Pei, Baoming Qin, Xichen Bao, Xihua Zhu, Christina Benda, Miguel A. Esteban, Qiang Zhuang
Publikováno v:
Current Opinion in Cell Biology. 25:208-214
The generation of induced pluripotent stem (iPS) cells by exogenous transcription factors involves a comprehensive rearrangement of cellular functions, including the microRNA profile. The resulting cell lines are similar to embryonic stem (ES) cells
Autor:
Qiang Zhuang, Yanhua Li, Duanqing Pei, Christina Benda, Ya Zhang, Ting Zhou, Miguel A. Esteban, Regina Grillari-Voglauer, Yinghua Huang, Sarah Dunzinger, Jenny Cy Ho, Hung-Fat Tse, Xichen Bao, Yu Wang, Jiayin Yang, Johannes Grillari
Publikováno v:
Nature Protocols. 7:2080-2089
Human induced pluripotent stem cells (iPSCs) have been generated with varied efficiencies from multiple tissues. Yet, acquiring donor cells is, in most instances, an invasive procedure that requires laborious isolation. Here we present a detailed pro
Autor:
Carl Ward, Hui Zhang, Christina Benda, Wenjuan Li, Zhiwei Luo, Mazid Md. Abdul, Xiaofen Zhong, Yinghua Huang, Xichen Bao, Micky D. Tortorella, Andrew P. Hutchins, Shahzina Kanwal, Jianguo Zhou, Muhammad Jadoon Khan, Jiayu Chen, Xiangpeng Guo, Meng Zhang, David P. Ibañez, Tanveer Ahmed, Wenxia Fan, Xihua Zhu, Yan Xu, Ping Liu, Qiang Zhuang, Jiayin Yang, Hung-Fat Tse, Yulin Liu, Zhongzhou Yang, Dehao Huang, Zhijian Huang, Shaorong Gao, Baoming Qin, Xiuling Fu, Bushra Mirza, Miguel A. Esteban
Publikováno v:
Nature Cell Biology. 20:1227-1227
In the version of this Article originally published, in Fig. 2c, the '+' sign and 'OSKM' were superimposed in the label '+OSKM'. In Fig. 4e, in the labels, all instances of 'Ant' should have been 'Anti-'. And, in Fig. 7a, the label '0.0' was misplace
Autor:
Yue Ying, Qiang Zhuang, Meng Zhang, Liangxue Lai, Ping Zhao, Baoming Qin, Hung-Fat Tse, Hong Song, Baohua Liu, Yan Xu, Zhiwei Luo, Xiaohui Qiu, Yuan Li, Wen Li, Xichen Bao, Longqi Liu, Xingguo Liu, Hui Zhang, Su Ni, Miguel A. Esteban, Yinghua Huang, Yasong Wu, Christina Benda, Duanqing Pei, Wai-Yee Chan, Yujia Tang
Publikováno v:
Nature cell biology. 17(6)
We describe robust induction of autophagy during the reprogramming of mouse fibroblasts to induced pluripotent stem cells by four reprogramming factors (Sox2, Oct4, Klf4 and c-Myc), henceforth 4F. This process occurs independently of p53 activation,
Autor:
Andrew P. Hutchins, Huating Wang, Hao Sun, Biliang Zhang, Jun Wang, Miguel A. Esteban, Axel Schambach, Meng Zhang, Zhijian Huang, Jonathan Frampton, Wenxia Fan, Qiang Zhuang, Yuan Li, Xichen Bao, Weihua Tian, Dongye Wang, Christina Benda, Ping Zhao, Hongjie Yao, Xiangchun Li, Wenjuan Li, Baoming Qin, Zhiwei Luo, Minghui He, Mingze Yao, Leina Lu, Duanqing Pei, Yan Xu, Longqi Liu, Fenggong Cui, Yasong Wu, Hung-Fat Tse
Publikováno v:
Cell stem cell. 15(5)
SummaryReactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engage
Autor:
Eva Harreither, Hanna A. Rydberg, Christina Benda, Miguel A. Esteban, Helene L. Åmand, Frank Edenhofer, Oliver Hommerding, Lukas Fliedl, Regina Grillari-Voglauer, Nicole Borth, Vaibhav Jadhav, Bengt Nordén, Johannes Grillari, Duanqing Pei
Publikováno v:
Cell Regeneration
Scopus-Elsevier
Cell Regeneration, Vol 3, Iss 1 (2014)
Scopus-Elsevier
Cell Regeneration, Vol 3, Iss 1 (2014)
Background Oct4 is a transcription factor that plays a major role for the preservation of the pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic cells to induced pluripotent stem cells (iPSC) or other progenit