Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christina B. Shin"'
Autor:
Philip A. Vieira, Christina B. Shin, Netzahualcóyotl Arroyo-Currás, Gabriel Ortega, Weiwei Li, Arturo A. Keller, Kevin W. Plaxco, Tod E. Kippin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Clinical drug dosing would, ideally, be informed by high-precision, patient-specific data on drug metabolism. The direct determination of patient-specific drug pharmacokinetics (“peaks and troughs”), however, currently relies on cumbersome, labor
Externí odkaz:
https://doaj.org/article/cb05d35fd4ed4cbaaf276ac84facb255
Autor:
Tod E. Kippin, Kristina N. Elias, Kalysta N. Holder, Brooke D. Barger, Alvin S. Chiu, Laura L. Huerta Sanchez, Karen K. Szumlinski, Christina B. Shin, Matthew C. Kang, C. Leonardo Jimenez Chavez, Anne M. Fabella
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 46, iss 12
Neuropsychopharmacology
Neuropsychopharmacology
Cue-elicited drug-craving is a cardinal feature of addiction that intensifies (incubates) during protracted withdrawal. In a rat model, these addiction-related behavioral pathologies are mediated, respectively, by time-dependent increases in PI3K/Akt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d68e5f77886b5ec93b2518a85bb5e6
https://doi.org/10.1038/s41386-021-01064-9
https://doi.org/10.1038/s41386-021-01064-9
Autor:
Alvin S. Chiu, Matthew C. Kang, Laura L. Huerta Sanchez, Anne M. Fabella, Kalysta N. Holder, Brooke D. Barger, Kristina N. Elias, Christina B. Shin, C. Leonardo Jimenez Chavez, Tod E. Kippin, Karen K. Szumlinski
Cue-elicited drug-craving is a cardinal feature of addiction that intensifies (incubates) during protracted withdrawal. In a rat model, these addiction-related behavioral pathologies are mediated, respectively, by time-dependent increases in PI3K/Akt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5088db70f33b8a838e646dbcd24700e9
https://doi.org/10.21203/rs.3.rs-147118/v1
https://doi.org/10.21203/rs.3.rs-147118/v1
Autor:
John W. Hiller, John R. Shahin, Osnat Ben-Shahar, Melissa G. Wroten, Bailey W. Miller, Justin Courson, Alexis W. Ary, Tod E. Kippin, Karen K. Szumlinski, Micaela A. Ruppert-Majer, Christina B. Shin
Publikováno v:
Addiction biology, vol 24, iss 6
Szumlinski, KK; Ary, AW; Shin, CB; Wroten, MG; Courson, J; Miller, BW; et al.(2018). PI3K activation within ventromedial prefrontal cortex regulates the expression of drug-seeking in two rodent species.. Addiction biology. doi: 10.1111/adb.12696. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/8tq7466p
Szumlinski, KK; Ary, AW; Shin, CB; Wroten, MG; Courson, J; Miller, BW; et al.(2018). PI3K activation within ventromedial prefrontal cortex regulates the expression of drug-seeking in two rodent species.. Addiction biology. doi: 10.1111/adb.12696. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/8tq7466p
Phosphatidylinositide 3-kinases (PI3Ks) are intracellular signal transducer enzymes that recruit protein kinase B (aka Akt) to the cell membrane, the subsequent activation of which regulates many cellular functions. PI3K/Akt activity is up-regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2098ca5df2a4389b4197b51d56ba81
https://doi.org/10.1111/adb.12696
https://doi.org/10.1111/adb.12696
Autor:
Philip A, Vieira, Christina B, Shin, Netzahualcóyotl, Arroyo-Currás, Gabriel, Ortega, Weiwei, Li, Arturo A, Keller, Kevin W, Plaxco, Tod E, Kippin
Publikováno v:
Frontiers in Molecular Biosciences
Clinical drug dosing would, ideally, be informed by high-precision, patient-specific data on drug metabolism. The direct determination of patient-specific drug pharmacokinetics (“peaks and troughs”), however, currently relies on cumbersome, labor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5af6a0fc2e88be3c5b1ec1ca08e64a9f
https://pubmed.ncbi.nlm.nih.gov/31475156
https://pubmed.ncbi.nlm.nih.gov/31475156
Autor:
Michela M. Serchia, John R. Shahin, Karen K. Szumlinski, Christina B. Shin, Micaela A. Ruppert-Majer, Tod E. Kippin
Publikováno v:
Neuropharmacology. 102:103-110
Craving elicited by drug-associated cues intensifies across protracted drug abstinence - a phenomenon termed "incubation of craving" - and drug-craving in human addicts correlates with frontal cortical hyperactivity. Herein, we employed a rat model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d735543ec9e8c22e689d9b0158bd471
https://doi.org/10.1016/j.neuropharm.2015.10.038
https://doi.org/10.1016/j.neuropharm.2015.10.038
Autor:
Karen K. Szumlinski, Melissa G. Wroten, Bailey W. Miller, Philip A. Vieira, Christina B. Shin, Osnat Ben-Shahar, Tod E. Kippin, Arianne D. Sacramento, Hannah E. Silva
Publikováno v:
Addiction Biology. 22:629-639
In individuals with a history of drug taking, the capacity of drug-associated cues to elicit indices of drug craving intensifies or incubates with the passage of time during drug abstinence. This incubation of cocaine craving, as well as difficulties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1d16efbfa7bfb277c1094970c13c4de
https://doi.org/10.1111/adb.12354
https://doi.org/10.1111/adb.12354
Autor:
Jennifer Kim, Christina B. Shin, Taylor J. Templeton, Alvin S. Chiu, Karen K. Szumlinski, Ellen S. Gable, Philip A. Vieira, Tod E. Kippin
The incubation of cue-reinforced cocaine-seeking coincides with increased extracellular glutamate within the ventromedial prefrontal cortex (vmPFC). The vmPFC is comprised of two subregions that oppositely regulate drug-seeking, with infralimbic (IL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338a15f8123c7d146d297ba5ec430397
https://europepmc.org/articles/PMC6400061/
https://europepmc.org/articles/PMC6400061/
Autor:
Hui Li, Philippe Dauphin-Ducharme, Jacob Somerson, Claire H. Tran, Shaoguang Li, Christina B. Shin, Philip A. Vieira, Netzahualcóyotl Arroyo-Currás, Tod E. Kippin, Kevin W. Plaxco
Publikováno v:
Angewandte Chemie (International ed. in English), vol 56, iss 26
Angew. Chem. Int. Ed.
Angew. Chem. Int. Ed.
The real-time monitoring of specific analytes in situ in the living body would greatly advance our understanding of physiology and the development of personalized medicine. Because they are continuous (wash-free and reagentless) and are able to work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd9aa41d60e16e46d922161c242ffb4
https://escholarship.org/uc/item/3p9873j9
https://escholarship.org/uc/item/3p9873j9
Autor:
Arturo R. Zavala, Luyi Zhou, Arturo D. Garcia, Christina B. Shin, Carla Pruitt, Ronald E. See
Previous studies have shown that female rats exhibit different patterns of drug seeking during multiple phases of cocaine addiction when compared with males. However, the underlying mechanisms for these sex differences remain largely unknown. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5141db46953b9eca1bc191c068df37b
https://europepmc.org/articles/PMC3877704/
https://europepmc.org/articles/PMC3877704/