Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Christina B. Schroeter"'
Autor:
Saskia Räuber, Andreas Schulte-Mecklenbeck, Alice Willison, Ramona Hagler, Marius Jonas, Duygu Pul, Lars Masanneck, Christina B. Schroeter, Kristin S. Golombeck, Stefanie Lichtenberg, Christine Strippel, Marco Gallus, Andre Dik, Ruth Kerkhoff, Sumanta Barman, Katharina J. Weber, Stjepana Kovac, Melanie Korsen, Marc Pawlitzki, Norbert Goebels, Tobias Ruck, Catharina C. Gross, Werner Paulus, Guido Reifenberger, Michael Hanke, Oliver Grauer, Marion Rapp, Michael Sabel, Heinz Wiendl, Sven G. Meuth, Nico Melzer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Immune dysregulation is a hallmark of autoimmune diseases of the central nervous system (CNS), characterized by an excessive immune response, and primary CNS tumors (pCNS-tumors) showing a highly immunosuppressive parenchymal micr
Externí odkaz:
https://doaj.org/article/848c9d49598a4962b05d92211b97ff55
Autor:
I-Na Lu, Phyllis Fung-Yi Cheung, Michael Heming, Christian Thomas, Giovanni Giglio, Markus Leo, Merve Erdemir, Timo Wirth, Simone König, Christine A. Dambietz, Christina B. Schroeter, Christopher Nelke, Jens T. Siveke, Tobias Ruck, Luisa Klotz, Carmen Haider, Romana Höftberger, Christoph Kleinschnitz, Heinz Wiendl, Tim Hagenacker, Gerd Meyer zu Horste
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract 5q-associated spinal muscular atrophy (SMA) is a motoneuron disease caused by mutations in the survival motor neuron 1 (SMN1) gene. Adaptive immunity may contribute to SMA as described in other motoneuron diseases, yet mechanisms remain elus
Externí odkaz:
https://doaj.org/article/fb6284ab7fac4a1d86c729a732971fab
Autor:
Lars Masanneck, Jan Voth, Niklas Huntemann, Menekse Öztürk, Christina B. Schroeter, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-7 (2023)
Abstract Introduction Chronic inflammatory demyelinating polyneuropathy (CIDP) is one of the most common immune neuropathies leading to severe impairments in daily life. Current treatment options include intravenous immunoglobulins (IVIG), which are
Externí odkaz:
https://doaj.org/article/e2a8ca5a1952457eb18e62335e1064e3
Autor:
Lukas Theissen, Christina B. Schroeter, Niklas Huntemann, Saskia Räuber, Vera Dobelmann, Derya Cengiz, Alexander Herrmann, Kathrin Koch-Hölsken, Norbert Gerdes, Hao Hu, Philipp Mourikis, Amin Polzin, Malte Kelm, Hans-Peter Hartung, Sven G. Meuth, Christopher Nelke, Tobias Ruck
Publikováno v:
Cells, Vol 13, Iss 6, p 508 (2024)
Myasthenia gravis (MG) is a prototypical autoimmune disease of the neuromuscular junction (NMJ). The study of the underlying pathophysiology has provided novel insights into the interplay of autoantibodies and complement-mediated tissue damage. Exper
Externí odkaz:
https://doaj.org/article/f4973adcbfe1453db7ec94a458ee2aec
Autor:
Christina B. Schroeter, Leoni Rolfes, K. S. Sophie Gothan, Joel Gruchot, Alexander M. Herrmann, Stefanie Bock, Luca Fazio, Antonia Henes, Venu Narayanan, Steffen Pfeuffer, Christopher Nelke, Saskia Räuber, Niklas Huntemann, Eduardo Duarte-Silva, Vera Dobelmann, Petra Hundehege, Heinz Wiendl, Katharina Raba, Patrick Küry, David Kremer, Tobias Ruck, Thomas Müntefering, Thomas Budde, Manuela Cerina, Sven G. Meuth
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Cladribine is a synthetic purine analogue that interferes with DNA synthesis and repair next to disrupting cellular proliferation in actively dividing lymphocytes. The compound is approved for the treatment of multiple sclerosis (
Externí odkaz:
https://doaj.org/article/58f69881c3e94968a5c457db1a7af330
Autor:
Saskia Räuber, Christopher Nelke, Christina B. Schroeter, Sumanta Barman, Marc Pawlitzki, Jens Ingwersen, Katja Akgün, Rene Günther, Alejandra P. Garza, Michaela Marggraf, Ildiko Rita Dunay, Stefanie Schreiber, Stefan Vielhaber, Tjalf Ziemssen, Nico Melzer, Tobias Ruck, Sven G. Meuth, Michael Herty
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionGiven its wide availability and cost-effectiveness, multidimensional flow cytometry (mFC) became a core method in the field of immunology allowing for the analysis of a broad range of individual cells providing insights into cell subset c
Externí odkaz:
https://doaj.org/article/78b006fa17b54fda8cd7b21145d6c1ab
Autor:
Christopher Nelke, Christina B. Schroeter, Frauke Stascheit, Niklas Huntemann, Marc Pawlitzki, Alice Willison, Saskia Räuber, Nico Melzer, Ute Distler, Stefan Tenzer, Kai Stühler, Andreas Roos, Andreas Meisel, Sven G. Meuth, Tobias Ruck
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Therapeutic strategies targeting complement have revolutionized the treatment of myasthenia gravis (MG). However, a deeper understanding of complement modulation in the human system is required to improve treatment responses and identify off-target e
Externí odkaz:
https://doaj.org/article/fa42e69bd4ad4544a287b82ff2201d45
Autor:
Christina David, Tobias Ruck, Leoni Rolfes, Stine Mencl, Peter Kraft, Michael K. Schuhmann, Christina B. Schroeter, Robin Jansen, Friederike Langhauser, Anne K. Mausberg, Anke C. Fender, Sven G. Meuth, Christoph Kleinschnitz
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Typically defined as a thromboinflammatory disease, ischemic stroke features early and delayed inflammatory responses, which determine the extent of ischemia‐related brain damage. T and natural killer cells have been implicated in neuron
Externí odkaz:
https://doaj.org/article/47877b69926b4bd58690f27262adb83a
Autor:
Saskia Räuber, Moritz Förster, Julia Schüller, Alice Willison, Kristin S. Golombeck, Christina B. Schroeter, Menekse Oeztuerk, Robin Jansen, Niklas Huntemann, Christopher Nelke, Melanie Korsen, Katinka Fischer, Ruth Kerkhoff, Yana Leven, Patricia Kirschner, Tristan Kölsche, Petyo Nikolov, Mohammed Mehsin, Gelenar Marae, Alma Kokott, Duygu Pul, Julius Schulten, Niklas Vogel, Jens Ingwersen, Tobias Ruck, Marc Pawlitzki, Sven G. Meuth, Nico Melzer, David Kremer
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 787 (2024)
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) of still unclear etiology. In recent years, the search for biomarkers facilitating its diagnosis, prognosis, therapy response, and other parameters has gained increa
Externí odkaz:
https://doaj.org/article/fe3e82c8e18b4286bb1ed03123c6d48b
Autor:
Christopher Nelke, Frauke Stascheit, Carmen Eckert, Marc Pawlitzki, Christina B. Schroeter, Niklas Huntemann, Philipp Mergenthaler, Ercan Arat, Menekse Öztürk, Dirk Foell, Stefanie Schreiber, Stefan Vielhaber, Asmae Gassa, Henning Stetefeld, Michael Schroeter, Benjamin Berger, Andreas Totzeck, Tim Hagenacker, Sven G. Meuth, Andreas Meisel, Heinz Wiendl, Tobias Ruck
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background Myasthenic crisis (MC) and disease exacerbation in myasthenia gravis (MG) are associated with significant lethality and continue to impose a high disease burden on affected patients. Therefore, we sought to determine potential pre
Externí odkaz:
https://doaj.org/article/60c3ca9758a24509a314d4bfb1996d62