Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Christina B Wölwer"'
Autor:
Christina B Wölwer, Nathan Gödde, Luke B Pase, Imogen A Elsum, Krystle Y B Lim, Faruk Sacirbegovic, Carl R Walkley, Sarah Ellis, Shigeo Ohno, Fumio Matsuzaki, Sarah M Russell, Patrick O Humbert
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170295 (2017)
Erythroid enucleation is the process by which the future red blood cell disposes of its nucleus prior to entering the blood stream. This key event during red blood cell development has been likened to an asymmetric cell division (ACD), by which the e
Externí odkaz:
https://doaj.org/article/43b59eeb3ede421f8ae99d8004afa19b
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146201 (2016)
Although erythroid enucleation, the property of erythroblasts to expel their nucleus, has been known for 7ore than a century, surprisingly little is known regarding the molecular mechanisms governing this unique developmental process. Here we show th
Externí odkaz:
https://doaj.org/article/3d9578e7d6d54703a1bf6917ce307509
Autor:
Christina B Wölwer, Luke B Pase, Helen B Pearson, Nathan J Gödde, Kurt Lackovic, David C S Huang, Sarah M Russell, Patrick O Humbert
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142655 (2015)
Erythroid enucleation is critical for terminal differentiation of red blood cells, and involves extrusion of the nucleus by orthochromatic erythroblasts to produce reticulocytes. Due to the difficulty of synchronizing erythroblasts, the molecular mec
Externí odkaz:
https://doaj.org/article/8f9a9667a206456992fa2baa9f936e6b
Autor:
Carina Heydt, Christina B. Wölwer, Oscar Velazquez Camacho, Svenja Wagener-Ryczek, Roberto Pappesch, Janna Siemanowski, Jan Rehker, Florian Haller, Abbas Agaimy, Karl Worm, Thomas Herold, Nicole Pfarr, Wilko Weichert, Thomas Kirchner, Andreas Jung, Jörg Kumbrink, Wolfgang Goering, Irene Esposito, Reinhard Buettner, Axel M. Hillmer, Sabine Merkelbach-Bruse
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Background Gene fusions represent promising targets for cancer therapy in lung cancer. Reliable detection of multiple gene fusions is therefore essential. Methods Five commercially available parallel sequencing assays were evaluated for thei
Externí odkaz:
https://doaj.org/article/44bdb1f0d72743ee9374126053306f77
Publikováno v:
Blood. 140:2425-2426
Autor:
Heike Loeser, Christiane Bruns, Hakan Alakus, Thomas Zander, Reinhard Buettner, Christina B. Wölwer, Wolfgang Schroeder, Alexander Quaas, Axel M. Hillmer, Seung-Hun Chon, Florian Gebauer
Publikováno v:
Cancers
Volume 12
Issue 7
Cancers, Vol 12, Iss 1743, p 1743 (2020)
Volume 12
Issue 7
Cancers, Vol 12, Iss 1743, p 1743 (2020)
Background: The loss of the Y chromosome in various malignant diseases has been described previously. There are no reliable information on the actual frequency, significance and homogeneity of Y chromosome loss (LoY) in esophageal adenocarcinoma (EAC
Autor:
Jana Wittig, Hakan Alakus, Axel M. Hillmer, Seung-Hun Chon, Sören Büsker, Heike Löser, Kat Folz-Donahue, Wolfgang Schröder, Alexander Quaas, Hans A. Schlößer, Christiane J. Bruns, Reinhard Büttner, Marek Franitza, Isabel Garcia-Marquez, Patrick Sven Plum, Oscar Velazquez Camacho, Christina B. Wölwer, Martin Thelen, Max Krämer, Janine Altmüller
Publikováno v:
Mol Oncol
Molecular Oncology
Molecular Oncology, Vol 14, Iss 6, Pp 1170-1184 (2020)
Molecular Oncology
Molecular Oncology, Vol 14, Iss 6, Pp 1170-1184 (2020)
Single‐cell transcriptomics have revolutionized our understanding of the cell composition of tumors and allowed us to identify new subtypes of cells. Despite rapid technological advancements, single‐cell analysis remains resource‐intense hamper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ed5a217ead71a45e679805215c7ab6
https://hdl.handle.net/21.11116/0000-000B-30C9-C
https://hdl.handle.net/21.11116/0000-000B-30C9-C
Cyclin A2 is an essential gene for development and in haematopoietic stem cells and therefore its functions in definitive erythropoiesis have not been investigated. We have ablated cyclin A2 in committed erythroid progenitors in vivo using erythropoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af1c8b890cdee1ac4ce702988653d40
https://europepmc.org/articles/PMC5351922/
https://europepmc.org/articles/PMC5351922/
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146201 (2016)
PLoS ONE
PLoS ONE
Although erythroid enucleation, the property of erythroblasts to expel their nucleus, has been known for 7ore than a century, surprisingly little is known regarding the molecular mechanisms governing this unique developmental process. Here we show th
Autor:
Sarah M. Russell, Patrick O. Humbert, Kurt Lackovic, David C.S. Huang, Christina B. Wölwer, Nathan Godde, Helen B. Pearson, Luke Pase
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 11, p e0142655 (2015)
PLoS ONE, Vol 10, Iss 11, p e0142655 (2015)
Erythroid enucleation is critical for terminal differentiation of red blood cells, and involves\ud extrusion of the nucleus by orthochromatic erythroblasts to produce reticulocytes. Due to\ud the difficulty of synchronizing erythroblasts, the molecul