Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Christina, Poetschke"'
Autor:
Anita Siller, Nadja T Hofer, Giulia Tomagra, Nicole Burkert, Simon Hess, Julia Benkert, Aisylu Gaifullina, Desiree Spaich, Johanna Duda, Christina Poetschke, Kristina Vilusic, Eva Maria Fritz, Toni Schneider, Peter Kloppenburg, Birgit Liss, Valentina Carabelli, Emilio Carbone, Nadine Jasmin Ortner, Jörg Striessnig
Publikováno v:
eLife, Vol 11 (2022)
In dopaminergic (DA) Substantia nigra (SN) neurons Cav2.3 R-type Ca2+-currents contribute to somatodendritic Ca2+-oscillations. This activity may contribute to the selective degeneration of these neurons in Parkinson’s disease (PD) since Cav2.3-kno
Externí odkaz:
https://doaj.org/article/9faa676ef6d24167b54187fd03cc356d
Autor:
Julia Benkert, Simon Hess, Shoumik Roy, Dayne Beccano-Kelly, Nicole Wiederspohn, Johanna Duda, Carsten Simons, Komal Patil, Aisylu Gaifullina, Nadja Mannal, Elena Dragicevic, Desirée Spaich, Sonja Müller, Julia Nemeth, Helene Hollmann, Nora Deuter, Yassine Mousba, Christian Kubisch, Christina Poetschke, Joerg Striessnig, Olaf Pongs, Toni Schneider, Richard Wade-Martins, Sandip Patel, Rosanna Parlato, Tobias Frank, Peter Kloppenburg, Birgit Liss
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Voltage-gated Ca2+ channels are thought to contribute to neurodegeneration of dopaminergic neurons. Here the authors find that the R-type channel Cav2.3 in substantia nigra dopaminergic neurons may contribute to neurodegeneration in a model of Parkin
Externí odkaz:
https://doaj.org/article/8271fb3221094175818e53f6966e1e51
Autor:
Nadja Mannal, Katharina Kleiner, Michael Fauler, Antonios Dougalis, Christina Poetschke, Birgit Liss
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. The
Externí odkaz:
https://doaj.org/article/c71a5a5bc85741aa9ab9e5f31a80507f
Autor:
Carsten Simons, Julia Benkert, Nora Deuter, Christina Poetschke, Olaf Pongs, Toni Schneider, Johanna Duda, Birgit Liss
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neuronal Ca2+ sensor proteins (NCS) transduce changes in Ca2+ homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration of dopaminergic (
Externí odkaz:
https://doaj.org/article/1272925511dc46fea958148d00f598ff
Autor:
Anita Siller, Nadja T Hofer, Giulia Tomagra, Nicole Burkert, Simon Hess, Julia Benkert, Aisylu Gaifullina, Desiree Spaich, Johanna Duda, Christina Poetschke, Kristina Vilusic, Eva Maria Fritz, Toni Schneider, Peter Kloppenburg, Birgit Liss, Valentina Carabelli, Emilio Carbone, Nadine Jasmin Ortner, Jörg Striessnig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d7fdda8bbed16576b5c1e092891c57
https://doi.org/10.7554/elife.67464.sa2
https://doi.org/10.7554/elife.67464.sa2
Autor:
Anita, Siller, Nadja T, Hofer, Giulia, Tomagra, Nicole, Burkert, Simon, Hess, Julia, Benkert, Aisylu, Gaifullina, Desiree, Spaich, Johanna, Duda, Christina, Poetschke, Kristina, Vilusic, Eva Maria, Fritz, Toni, Schneider, Peter, Kloppenburg, Birgit, Liss, Valentina, Carabelli, Emilio, Carbone, Nadine Jasmin, Ortner, Jörg, Striessnig
Publikováno v:
eLife. 11
In dopaminergic (DA)
Autor:
Spaich D, Giulia Tomagra, Eva Maria Fritz, Nicole Wiederspohn, Nadine J. Ortner, Anita Siller, Simon Hess, Emilio Carbone, Peter Kloppenburg, Aisylu S. Gaifullina, Toni Schneider, Jörg Striessnig, Nadja T. Hofer, Carabelli, Johanna Duda, Julia Benkert, Birgit Liss, Vilusic K, Christina Poetschke
In dopaminergic (DA) substantia nigra (SN) neurons Cav2.3 R-type Ca2+-currents contribute to somatodendritic Ca2+-oscillations. These may contribute to the selective degeneration of these neurons in Parkinson’s disease (PD) since Cav2.3-knockout is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a2e71d56663fde24e8a635b0aef31f3
https://doi.org/10.1101/2021.02.10.430224
https://doi.org/10.1101/2021.02.10.430224
Autor:
Nadja, Mannal, Katharina, Kleiner, Michael, Fauler, Antonios, Dougalis, Christina, Poetschke, Birgit, Liss
Publikováno v:
Frontiers in Synaptic Neuroscience
Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. The
Autor:
Carsten, Simons, Julia, Benkert, Nora, Deuter, Christina, Poetschke, Olaf, Pongs, Toni, Schneider, Johanna, Duda, Birgit, Liss
Publikováno v:
Frontiers in Molecular Neuroscience
Neuronal Ca2+ sensor proteins (NCS) transduce changes in Ca2+ homeostasis into altered signaling and neuronal function. NCS-1 activity has emerged as important for neuronal viability and pathophysiology. The progressive degeneration of dopaminergic (
Autor:
Christina Poetschke, Andrea Hetzel, Elena Dragicevic, Joerg Striessnig, Birgit Liss, Johanna Duda, Rafael Luján, Stephan Lammel, Robert C. Malenka, Falk Schlaudraff, Masahiko Watanabe, Michael Fauler, Julia Schiemann
Publikováno v:
Brain: a journal of neurology, vol 137, iss Pt 8
Dopamine midbrain neurons within the substantia nigra are particularly prone to degeneration in Parkinson’s disease. Their selective loss causes the major motor symptoms of Parkinson’s disease, but the causes for the high vulnerability of SN DA n