Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Christina, Mack"'
Autor:
Chinenye Ugoji, Julien Heidt, Joan Largent, Emily Bratton, Laura Hester, Sareh Keshavarzi, Stuart Turner, Christina Mack
Publikováno v:
Frontiers in Drug Safety and Regulation, Vol 4 (2024)
Natural history studies (NHS) can support regulatory decision-making at different stages of the drug product life cycle and are especially important in the context of rare diseases, which are associated with not only delayed or erroneous diagnoses bu
Externí odkaz:
https://doaj.org/article/47c0a0df1eb247d98dec8d6014c9d647
Autor:
Emma Brinkley, Kendall Knuth, Tom Kwon, Christina Mack, Heidi Leister-Tebbe, Weihand Bao, Matthew W Reynolds, Nancy Dreyer
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-5 (2023)
Abstract In January 2021, 999 COVID-19 positive adults in the US enrolled in an online, direct-to-patient registry to describe daily symptom severity and progression over 28 days. The most commonly reported and persistent symptoms were fatigue, heada
Externí odkaz:
https://doaj.org/article/1edf2395e5d44b06ae01d57381828a82
Autor:
Stephen M. Kissler, James A. Hay, Joseph R. Fauver, Christina Mack, Caroline G. Tai, Deverick J. Anderson, David D. Ho, Nathan D. Grubaugh, Yonatan H. Grad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample of 94,812 longitudinal RT-qPCR measurements from anterior nares and oropharyngeal swabs, we identified 71 ind
Externí odkaz:
https://doaj.org/article/3f1d1f8bc0de464083a926828fffe180
Autor:
Gerd Rippin, Joan Largent, Wilhelmina Elisabeth Hoogendoorn, Héctor Sanz, Jaclyn Bosco, Christina Mack
Publikováno v:
Frontiers in Drug Safety and Regulation, Vol 3 (2024)
Though there is only one term for the gold standard of Randomized Controlled Trials the terminology used for controlled research involving external data is diverse. Common terms include External Comparator/Control Arm study, Externally Controlled Tri
Externí odkaz:
https://doaj.org/article/216f765427e34c1eb7ef3ac3d3a998cb
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract In this work, we aim to accurately predict the number of hospitalizations during the COVID-19 pandemic by developing a spatiotemporal prediction model. We propose HOIST, an Ising dynamics-based deep learning model for spatiotemporal COVID-19
Externí odkaz:
https://doaj.org/article/0fe889f0e94f438d968e4febe87e0aff
Autor:
Rico Zuchowski, Simone Schito, Friederike Neuheuser, Philipp Menke, Daniel Berger, Niels Hollmann, Srushti Gujar, Lea Sundermeyer, Christina Mack, Astrid Wirtz, Oliver H. Weiergräber, Tino Polen, Michael Bott, Stephan Noack, Meike Baumgart
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-22 (2023)
Abstract Background Amino acid production features of Corynebacterium glutamicum were extensively studied in the last two decades. Many metabolic pathways, regulatory and transport principles are known, but purely rational approaches often provide on
Externí odkaz:
https://doaj.org/article/9c5ade4a5f224a7588d478b17d0954e2
Autor:
Lea Sundermeyer, Jan-Gerrit Folkerts, Benita Lückel, Christina Mack, Meike Baumgart, Michael Bott
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT For many bacterial proteins, specific localizations within the cell have been demonstrated, but enzymes involved in central metabolism are usually considered to be homogenously distributed within the cytoplasm. Here, we provide an example fo
Externí odkaz:
https://doaj.org/article/ae910c5bebf745a19024faa120a1b4a5
Autor:
Angela Kranz, Tino Polen, Christian Kotulla, Annette Arndt, Graziella Bosco, Michael Bussmann, Ava Chattopadhyay, Annette Cramer, Cedric-Farhad Davoudi, Ursula Degner, Ramon Diesveld, Raphael Freiherr von Boeselager, Kim Gärtner, Cornelia Gätgens, Tobias Georgi, Christian Geraths, Sabine Haas, Antonia Heyer, Max Hünnefeld, Takeru Ishige, Armin Kabus, Nicolai Kallscheuer, Larissa Kever, Simon Klaffl, Britta Kleine, Martina Kočan, Abigail Koch-Koerfges, Kim J. Kraxner, Andreas Krug, Aileen Krüger, Andreas Küberl, Mohamed Labib, Christian Lange, Christina Mack, Tomoya Maeda, Regina Mahr, Stephan Majda, Andrea Michel, Xenia Morosov, Olga Müller, Arun M. Nanda, Jens Nickel, Jennifer Pahlke, Eugen Pfeifer, Laura Platzen, Paul Ramp, Doris Rittmann, Steffen Schaffer, Sandra Scheele, Stephanie Spelberg, Julia Schulte, Jens-Eric Schweitzer, Georg Sindelar, Ulrike Sorger-Herrmann, Markus Spelberg, Corinna Stansen, Apilaasha Tharmasothirajan, Jan van Ooyen, Philana van Summeren-Wesenhagen, Michael Vogt, Sabrina Witthoff, Lingfeng Zhu, Bernhard J. Eikmanns, Marco Oldiges, Georg Schaumann, Meike Baumgart, Melanie Brocker, Lothar Eggeling, Roland Freudl, Julia Frunzke, Jan Marienhagen, Volker F. Wendisch, Michael Bott
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Abstract Corynebacterium glutamicum is the major host for the industrial production of amino acids and has become one of the best studied model organisms in microbial biotechnology. Rational strain construction has led to an improvement of producer s
Externí odkaz:
https://doaj.org/article/40c95f8ff8694597bb7bae3c633c682c
Autor:
James A Hay, Stephen M Kissler, Joseph R Fauver, Christina Mack, Caroline G Tai, Radhika M Samant, Sarah Connolly, Deverick J Anderson, Gaurav Khullar, Matthew MacKay, Miral Patel, Shannan Kelly, April Manhertz, Isaac Eiter, Daisy Salgado, Tim Baker, Ben Howard, Joel T Dudley, Christopher E Mason, Manoj Nair, Yaoxing Huang, John DiFiori, David D Ho, Nathan D Grubaugh, Yonatan H Grad
Publikováno v:
eLife, Vol 11 (2022)
Background: The combined impact of immunity and SARS-CoV-2 variants on viral kinetics during infections has been unclear. Methods: We characterized 1,280 infections from the National Basketball Association occupational health cohort identified betwee
Externí odkaz:
https://doaj.org/article/f3b2fd867b064cf7aabc11afd98908fa
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Inositols (cyclohexanehexols) comprise nine isomeric cyclic sugar alcohols, several of which occur in all domains of life with various functions. Many bacteria can utilize inositols as carbon and energy sources via a specific pathway involvi
Externí odkaz:
https://doaj.org/article/d9a3acc54cdf4ef585f10b05418c41f5