Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Christina, Helmling"'
Autor:
Christina Helmling, Dean-Paulos Klötzner, Florian Sochor, Rachel Anne Mooney, Anna Wacker, Robert Landick, Boris Fürtig, Alexander Heckel, Harald Schwalbe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Riboswitches are RNA-based regulatory elements, which regulate downstream gene expression by binding of small molecular weight ligands. Here the authors demonstrate the molecular mechanism of a transcriptional riboswitch that integrates changes in tr
Externí odkaz:
https://doaj.org/article/cba69ad002cb4eff9de91d0845331311
Autor:
Hannah Steinert, Florian Sochor, Anna Wacker, Janina Buck, Christina Helmling, Fabian Hiller, Sara Keyhani, Jonas Noeske, Steffen Grimm, Martin M Rudolph, Heiko Keller, Rachel Anne Mooney, Robert Landick, Beatrix Suess, Boris Fürtig, Jens Wöhnert, Harald Schwalbe
Publikováno v:
eLife, Vol 6 (2017)
In bacteria, the regulation of gene expression by cis-acting transcriptional riboswitches located in the 5'-untranslated regions of messenger RNA requires the temporal synchronization of RNA synthesis and ligand binding-dependent conformational refol
Externí odkaz:
https://doaj.org/article/9ca65ffa9a5e4f31902497f97157d4fa
Publikováno v:
ACS Symposium Series ISBN: 9780841297616
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fff49015aa2a338e8c5ce820f74261e
https://doi.org/10.1021/bk-2022-1417.ch002
https://doi.org/10.1021/bk-2022-1417.ch002
Autor:
Baocheng Liu, Z. Hong Zhou, Ryan Cheng, Lukas Sušac, Juli Feigon, Yao He, Christina Helmling, Yaqiang Wang
Publikováno v:
Nature
Nature, vol 593, iss 7859
Nature, vol 593, iss 7859
Telomerase is unique among the reverse transcriptases in containing a noncoding RNA (known as telomerase RNA (TER)) that includes a short template that is used for the processive synthesis of G-rich telomeric DNA repeats at the 3′ ends of most euka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e049cbf185b6c272ade4c583a529735
https://pubmed.ncbi.nlm.nih.gov/33981033
https://pubmed.ncbi.nlm.nih.gov/33981033
Autor:
Swapnil V. Ghodge, Kaustav Biswas, Andrei A. Golosov, Tomi K. Sawyer, Christina Helmling, Christian N. Cunningham, Vikram K. Mulligan, Parisa Hosseinzadeh, Dan Sindhikara, Jennifer Johnston, Anna Sophia Kamenik, Stephanie Maria Linker, Sereina Riniker, Emel Adaligil, Wayne J. Fairbrother, Dehua Pei, Alec N. Flyer, Lauren G. Monovich, Amy C. Doty, Cassie M. Jarvis, Erik V. Munsell, Ruchia Duggal, Jerome Hochman
Autor:
S. Th. Sigurdsson, Christina Helmling, Kai A. Schnorr, Dnyaneshwar B. Gophane, Dominic Barthelmes, Erhan Can Cetiner, Boris Fürtig, Elke Stirnal, Markus Gränz, K Pasemann, Nusrat S. Qureshi, Anna Wacker, H R A Jonker, Harald Schwalbe
Publikováno v:
Journal of Biomolecular NMR. 68:53-63
Paramagnetic relaxation enhancement (PRE) is a versatile tool for NMR spectroscopic structural and kinetic studies in biological macromolecules. Here, we compare the quality of PRE data derived from two spin labels with markedly different dynamic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73991bae917c13d8c103b208c71960f0
https://doi.org/10.1007/s10858-017-0114-9
https://doi.org/10.1007/s10858-017-0114-9
Autor:
Harald Schwalbe, Michael T. Wolfinger, Ivo L. Hofacker, Anna Wacker, Christina Helmling, Boris Fürtig, Martin Hengesbach
Publikováno v:
ResearcherID
Gene repression induced by the formation of transcriptional terminators represents a prime example for the coupling of RNA synthesis, folding, and regulation. In this context, mapping the changes in available conformational space of transcription int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538cb54867bd904fac0c8a848e45a357
https://doi.org/10.1021/jacs.6b10429
https://doi.org/10.1021/jacs.6b10429
Autor:
H R A Jonker, Erhan Can Cetiner, Harald Schwalbe, S. Th. Sigurdsson, Christina Helmling, Christian Grünewald, Dnyaneshwar B. Gophane
Publikováno v:
Journal of biomolecular NMR. 73(12)
Paramagnetic relaxation enhancement (PRE) can be used to determine long-range distance restraints in biomolecules. The PREs are typically determined by analysis of intensity differences in HSQC experiments of paramagnetic and diamagnetic spin labels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18f78571bc5e9cbc76066c749fe5f5a
https://pubmed.ncbi.nlm.nih.gov/31606877
https://pubmed.ncbi.nlm.nih.gov/31606877
Autor:
Robbin Schnieders, Heidi Zetzsche, Sara Keyhani, Christina Helmling, Boris Fürtig, Christian Richter, Helena Kovacs, Harald Schwalbe
Publikováno v:
Journal of Biomolecular NMR. 64:207-221
In RNA secondary structure determination, it is essential to determine whether a nucleotide is base-paired and not. Base-pairing of nucleotides is mediated by hydrogen bonds. The NMR characterization of hydrogen bonds relies on experiments correlatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96229bb9d08bd07013129a97bc30ecc8
https://doi.org/10.1007/s10858-016-0021-5
https://doi.org/10.1007/s10858-016-0021-5
Autor:
Florian Sochor, Rachel A. Mooney, Dean-Paulos Klötzner, Harald Schwalbe, Alexander Heckel, Christina Helmling, Robert Landick, Boris Fürtig, Anna Wacker
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Transcriptional riboswitches modulate downstream gene expression by a tight coupling of ligand-dependent RNA folding kinetics with the rate of transcription. RNA folding pathways leading to functional ON and OFF regulation involve the formation of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77f74dfbbd2c6b5a70cc72f7d9d8f57
http://europepmc.org/articles/PMC5838219
http://europepmc.org/articles/PMC5838219