Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Christina, Grimm"'
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Hyperactivity of the human anterior hippocampus has been reported to spread from its CA1 subfield to the subiculum around the onset of first-episode psychosis and could be a cellular target for early therapeutic intervention in the schizophr
Externí odkaz:
https://doaj.org/article/5b374a3fdc324dceb52418001eaa4730
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101761- (2022)
Summary: Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain network dynamics. Here, we
Externí odkaz:
https://doaj.org/article/62b2b6efa5414bfb98b1419f408ff1b8
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In the past decade, the idea that single populations of neurons support cognition and behavior has gradually given way to the realization that connectivity matters and that complex behavior results from interactions between remote yet anatom
Externí odkaz:
https://doaj.org/article/e748c4ee387d49cfbeecb4fe7bff35b5
Autor:
Julian Kanne, Michelle Hussong, Jörg Isensee, Álvaro Muñoz-López, Jan Wolffgramm, Felix Heß, Christina Grimm, Sergey Bessonov, Lydia Meder, Jie Wang, H. Christian Reinhardt, Margarete Odenthal, Tim Hucho, Reinhard Büttner, Daniel Summerer, Michal R. Schweiger
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-15 (2021)
Abstract Non-coding RNA from pericentromeric satellite repeats are involved in stress-dependent splicing processes, maintenance of heterochromatin, and are required to protect genome stability. Here we show that the long non-coding satellite III RNA
Externí odkaz:
https://doaj.org/article/0959e03a10f843b1a00d0335705383db
Evaluation of a Prognostic Epigenetic Classification System in Chronic Lymphocytic Leukemia Patients
Autor:
Christina Grimm, Carmen Diana Herling, Anastasia Komnidi, Michelle Hussong, Karl-Anton Kreuzer, Michael Hallek, Michal R. Schweiger
Publikováno v:
Biomarker Insights, Vol 17 (2022)
Background: Methylation at 5 CpG sites was previously shown to classify chronic lymphocytic leukemia (CLL) into 3 prognostic subgroups. Here, we aimed to validate the marker set in an additional cohort and to evaluate its clinical utility for CLL pat
Externí odkaz:
https://doaj.org/article/5bb5b4538a634d018c8c66945fbc4cee
Autor:
Claudia Perne, Sophia Peters, Maria Cartolano, Sukanya Horpaopan, Christina Grimm, Janine Altmüller, Anna K Sommer, Axel M Hillmer, Holger Thiele, Margarete Odenthal, Gabriela Möslein, Ronja Adam, Sugirthan Sivalingam, Jutta Kirfel, Michal R Schweiger, Martin Peifer, Isabel Spier, Stefan Aretz
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259185 (2021)
The spectrum of somatic genetic variation in colorectal adenomas caused by biallelic pathogenic germline variants in the MSH3 gene, was comprehensively analysed to characterise mutational signatures and identify potential driver genes and pathways of
Externí odkaz:
https://doaj.org/article/6bc898b6a61f4b74a29ec7af0aec5145
Autor:
Sabrina Grasse, Matthias Lienhard, Steffen Frese, Martin Kerick, Anne Steinbach, Christina Grimm, Michelle Hussong, Jana Rolff, Michael Becker, Felix Dreher, Uwe Schirmer, Stefan Boerno, Anna Ramisch, Gunda Leschber, Bernd Timmermann, Christian Grohé, Heike Lüders, Martin Vingron, Iduna Fichtner, Sebastian Klein, Margarete Odenthal, Reinhard Büttner, Hans Lehrach, Holger Sültmann, Ralf Herwig, Michal R. Schweiger
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide and is primarily treated with radiation, surgery, and platinum-based drugs like cisplatin and carboplatin. The major challenge in the t
Externí odkaz:
https://doaj.org/article/84b7234bcdf146459a94256898e040dd
Autor:
Michal R. Schweiger, Hans Lehrach, Holger Sültmann, Thorsten Schlomm, Guido Sauter, Mark A. Rubin, Francesca Demichelis, Ronald Simon, Markus Graefen, Christoph Plass, Rainer Claus, Bernd Timmermann, Andrea Wunderlich, Christina Röhr, Melanie Isau, Behnam Sayanjali, Christina Grimm, Andreas Dahl, Ruprecht Kuner, Jan C. Brase, Mark Laible, Maria Fälth, Martin Kerick, Axel Fischer, Stefan T. Börno
PDF file - 175K, Table S1 Clinical data and sequencing statistics. Table S2: Oligonucleotides for library construction and quantification and BS-MS-primers used for validation of MeDIP-Seq data. Table S3 Top 100 differentially methylated regions betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07571f0bfd4cc385a8bab0bc4b4dacdf
https://doi.org/10.1158/2159-8290.22528502.v1
https://doi.org/10.1158/2159-8290.22528502.v1
Autor:
Michal R. Schweiger, Hans Lehrach, Holger Sültmann, Thorsten Schlomm, Guido Sauter, Mark A. Rubin, Francesca Demichelis, Ronald Simon, Markus Graefen, Christoph Plass, Rainer Claus, Bernd Timmermann, Andrea Wunderlich, Christina Röhr, Melanie Isau, Behnam Sayanjali, Christina Grimm, Andreas Dahl, Ruprecht Kuner, Jan C. Brase, Mark Laible, Maria Fälth, Martin Kerick, Axel Fischer, Stefan T. Börno
PDF file - 64K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5158b1a8c7536ed248f2965175506a6
https://doi.org/10.1158/2159-8290.22528508
https://doi.org/10.1158/2159-8290.22528508
Autor:
Michal R. Schweiger, Hans Lehrach, Holger Sültmann, Thorsten Schlomm, Guido Sauter, Mark A. Rubin, Francesca Demichelis, Ronald Simon, Markus Graefen, Christoph Plass, Rainer Claus, Bernd Timmermann, Andrea Wunderlich, Christina Röhr, Melanie Isau, Behnam Sayanjali, Christina Grimm, Andreas Dahl, Ruprecht Kuner, Jan C. Brase, Mark Laible, Maria Fälth, Martin Kerick, Axel Fischer, Stefan T. Börno
PDF file - 947K, Supplementary Fig. S1. Differential methylations in PCa validated by BS-MS experiments. Supplementary Fig. S2. DNA-Methylomes of prostate cancer differ significantly from normal tissues. Supplementary Fig. S3. Global differences in D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eea8631ec06151a01784680eb84a063
https://doi.org/10.1158/2159-8290.22528505.v1
https://doi.org/10.1158/2159-8290.22528505.v1