Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christina, Borgeest"'
Methoxychlor-Induced Ovarian Follicle Toxicity in Mice: Dose and Exposure Duration-Dependent Effects
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 95:219-224
BACKGROUND Methoxychlor (MXC) is specifically known to target ovarian antral follicles, increasing atresia (death via apoptosis) in them. This is of concern because females are born with a finite pool of ovarian follicles. Only limited studies have e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e2471d9a102ba8ca1bc2fcae7c0d6e3
https://doi.org/10.1002/bdrb.21007
https://doi.org/10.1002/bdrb.21007
Autor:
Rupesh K. Gupta, Chuck R. Greenfeld, Jodi A. Flaws, Kathleen S. Hruska, Patricia B. Hoyer, Kimberly P. Miller, Christina Borgeest
Publikováno v:
Biology of Reproduction. 70:1828-1835
Methoxychlor (MXC) is an organochlorine pesticide that increases the rate of ovarian atresia. To date, little is known about the mechanism by which MXC induces atresia. Because Bcl-2 (an antiapoptotic factor), Bax (a proapoptotic factor), gonadotropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ab71ed5bda15b0e68dcaa63a63a959b
https://doi.org/10.1095/biolreprod.103.022889
https://doi.org/10.1095/biolreprod.103.022889
Publikováno v:
Ovarian Toxicology ISBN: 9780415287951
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae9d2ffe18dd874c8466495e7395b02b
https://doi.org/10.1201/9780203509234.ch3
https://doi.org/10.1201/9780203509234.ch3
Autor:
Christina, Borgeest, Kimberly P, Miller, Rupesh, Gupta, Chuck, Greenfeld, Kathleen S, Hruska, Patricia, Hoyer, Jodi A, Flaws
Publikováno v:
Biology of reproduction. 70(6)
Methoxychlor (MXC) is an organochlorine pesticide that increases the rate of ovarian atresia. To date, little is known about the mechanism by which MXC induces atresia. Because Bcl-2 (an antiapoptotic factor), Bax (a proapoptotic factor), gonadotropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82247caa974bf4e717b5b691835089d5
https://pubmed.ncbi.nlm.nih.gov/14973267
https://pubmed.ncbi.nlm.nih.gov/14973267
Publikováno v:
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. 273(2)
Smad 3 is a signaling intermediate for the transforming growth factor beta (TGFβ) family; however, little is known about the role this protein plays in the regulation of the ovarian surface epithelium (OSE). Using a transgenic mouse model, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa23c50120d3b194237d6312a10f323d
https://pubmed.ncbi.nlm.nih.gov/12845704
https://pubmed.ncbi.nlm.nih.gov/12845704
Publikováno v:
Toxicology and applied pharmacology. 198(2)
Chemicals found in the environment as industrial byproducts or pollutants as well as those that are prescribed or part of our daily lives can have multiple effects on the human body. The manner in which we are exposed, and the levels we are exposed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7005a304f5f7a07ad19e74482cccc9d5
https://pubmed.ncbi.nlm.nih.gov/15236949
https://pubmed.ncbi.nlm.nih.gov/15236949
Publikováno v:
Frontiers in Bioscience. 7:d1941
Endocrine disrupting chemicals (EDCs) are natural or synthetic chemicals that mimic, enhance, or inhibit endogenous hormones. In this article, we review possible targets of EDCs within the ovary and explore whether EDCs may be acting as estrogen mimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ceafa037578b03853fa855b0690ebf
https://doi.org/10.2741/borgees
https://doi.org/10.2741/borgees
Publikováno v:
Anatomical Record; Aug2003, Vol. 273 Issue 2, p681-686, 6p