Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christin Wallstab"'
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-20 (2018)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a major health burden in need for new medication. To identify potential drug targets a genomic study was performed in lipid-laden primary human hepatocyte (PHH) and human hepatoma cell
Externí odkaz:
https://doaj.org/article/73c7d279cc8540e5b1764f7945903e77
Autor:
Jürgen Borlak, Theresa Schulz, Nikolaus Berndt, Dimitra Eleftheriadou, Hermann-Georg Holzhütter, Daniel Seehofer, Georg Damm, Christin Wallstab
Publikováno v:
The FEBS Journal. 284:3245-3261
The liver responds to elevated plasma concentrations of free fatty acids (FFAs) with an enhanced uptake of FFAs and their esterification to triacylglycerol (TAG). On the long term, this may result in massive hepatic TAG accumulation called steatosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bd9cfa79936e95f4f6b7c6add0be8e
https://doi.org/10.1111/febs.14189
https://doi.org/10.1111/febs.14189
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-20 (2018)
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-20 (2018)
Background Non-alcoholic fatty liver disease (NAFLD) is a major health burden in need for new medication. To identify potential drug targets a genomic study was performed in lipid-laden primary human hepatocyte (PHH) and human hepatoma cell cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac180d44af045083284da43cd2d91ec
https://doi.org/10.1186/s12920-018-0438-7
https://doi.org/10.1186/s12920-018-0438-7