Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christin Poulson"'
Autor:
Alexa Guerrero-Alba, Sandhya Bansal, Aryan N. Sankpal, Geetanjali Mitra, Mohammad Rahman, Ranjithkumar Ravichandran, Christin Poulson, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, T. Mohanakumar, Narendra V. Sankpal
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
In the realm of biomedical advancement, extracellular vesicles (EVs) are revolutionizing our capacity to diagnose, monitor, and predict disease progression. However, the comprehensive exploration and clinical application of EVs face significant limit
Externí odkaz:
https://doaj.org/article/c2b1881291d84e4ab010a63039134313
Autor:
Ranjithkumar Ravichandran, Yoshihiro Itabashi, Timothy Fleming, Sandhya Bansal, Sara Bowen, Christin Poulson, Ankit Bharat, Ross Bremner, Michael Smith, Thalachallour Mohanakumar
Publikováno v:
American Journal of Transplantation. 22:2180-2194
To determine the effects and immunological mechanisms of low-dose interleukin-2 (IL-2) in a murine model of chronic cardiac allograft rejection (BALB/c to C57BL/6) after costimulatory blockade consisting of MR1 (250 μg/ip day 0) and CTLA4-Ig (200 μ
Autor:
Thalachallour Mohanakumar, Christin Poulson, Ashwini Arjuna, Sandhya Bansal, Michael A. Smith, Ross M. Bremner, Sofya Tokman, Sudhir Perincheri
Publikováno v:
The Journal of Heart and Lung Transplantation. 41:24-33
Background Chronic lung allograft dysfunction in lung transplant recipients (LTxRs) has 2 phenotypes: obstructive bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS). Our goal was to define distinct immunologic markers of
Autor:
Brian Tiffany, Sandhya Bansal, Christin Poulson, Thalachallour Mohanakumar, Ross M. Bremner, Timothy P. Fleming, Sudhir Perincheri
Publikováno v:
The Journal of Immunology. 207:2405-2410
Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causes severe acute respiratory syndrome. mRNA vaccines directed at the SARS-CoV-2 spike protein resulted in development of Abs and protective immunity. To determine the mechanism, we anal
Autor:
Yoshihiro Itabashi, Ranjithkumar Ravichandran, Sandhya Bansal, Chiahsuan Chin, Christin Poulson, Angara Sureshbabu, Sumi Sukumaran Nair, Sudhir Perincheri, T. Mohanakumar
Publikováno v:
Transplant Immunology. 75:101702
Antibodies against donor human leukocyte antigen are a risk factor for chronic immune injury (CII) following renal transplantation; however, it is often not detectable. The main goal of this study is to gain new insights into the kinetics of exosome
Autor:
Mohammad Rahman, Christin Poulson, Wei Liu, Thalachallour Mohanakumar, Timothy P. Fleming, Ranjithkumar Ravichandran, Michael W. Smith, Sandhya Bansal, Ross M. Bremner, Yoshihiro Itabashi
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 40(12)
Background In human lung transplant recipients, a decline in club cell secretory protein (CCSP) in bronchoalveolar lavage fluid has been associated with chronic lung allograft dysfunction (CLAD) as well as the induction of exosomes and immune respons
Autor:
Yoshihiro Itabashi, Sandhya Bansal, Ankit Bharat, Ross M. Bremner, Michael A. Smith, Thalachallour Mohanakumar, Sudhir Perincheri, Christin Poulson
Publikováno v:
Cell Immunol
Human lung transplant recipients undergoing rejection induce circulatory exosomes with lung self-antigens (SAgs), K-alpha 1 Tubulin and Collagen V, and immunization of C57BL/6 mice with exosomes induced obliterative airway disease (HEI-OAD). We analy
Autor:
Timothy P. Fleming, Ramsey R. Hachem, Ankit Bharat, Ashraf Omar, John Lee, Ajit P. Limaye, Sandhya Bansal, Ross M. Bremner, Michael A. Smith, Christin Poulson, Thalachallour Mohanakumar
Publikováno v:
Transplant Immunology. 69:101480
Background Chronic lung transplant rejection occurs in over 50% of lung transplant recipients and mechanism of chronic rejection is unknown. Evaluation of potential mechanism of exosomes from lung transplant recipients diagnosed with respiratory vira
Autor:
Thalachallour Mohanakumar, Timothy P. Fleming, Yoshihiro Itabashi, Wei Liu, Ranjithkumar Ravichandran, Christin Poulson
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S31
Purpose Aim of the study is to determine the effect of low dose interleukin-2 (IL-2) therapy on the kinetics of induction of circulating exosomes with tolerance markers (PDL1, CD73) and their role in abrogating chronic rejection following murine hete