Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christin Pelzel"'
Autor:
Johnathan Ho, Christin Pelzel, Andreas Begitt, Maureen Mee, Hany M Elsheikha, David J Scott, Uwe Vinkemeier
Publikováno v:
PLoS Biology, Vol 14, Iss 10, p e2000117 (2016)
STAT2 is the quintessential transcription factor for type 1 interferons (IFNs), where it functions as a heterodimer with STAT1. However, the human and murine STAT2-deficient phenotypes suggest important additional and currently unidentified type 1 IF
Externí odkaz:
https://doaj.org/article/f2562fdce7bf4c919c2757e5572c65b6
Autor:
Uwe Vinkemeier, Hany M. Elsheikha, Johnathan On Kay Ho, Christin Pelzel, David J. Scott, Maureen Mee, Andreas Begitt
Publikováno v:
PLoS Biology
PLoS Biology, Vol 14, Iss 10, p e2000117 (2016)
PLoS Biology, Vol 14, Iss 10, p e2000117 (2016)
STAT2 is the quintessential transcription factor for type 1 interferons (IFNs), where it functions as a heterodimer with STAT1. However, the human and murine STAT2-deficient phenotypes suggest important additional and currently unidentified type 1 IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83be1af40c0e1b430a392e7a86ba5100
https://pubmed.ncbi.nlm.nih.gov/27780205
https://pubmed.ncbi.nlm.nih.gov/27780205
Publikováno v:
Molecular Cell
Summary Signal transducer and activator of transcription 1 (STAT1) is activated by tyrosine phosphorylation upon interferon-γ (IFNγ) stimulation, which results in the expression of genes with antiproliferative and immunomodulatory functions. The in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392a82ecb4d8d19c3360cb89cf20897a
https://pubmed.ncbi.nlm.nih.gov/23582260
https://pubmed.ncbi.nlm.nih.gov/23582260
Publikováno v:
Cytokine. 76:83
Interferons (IFN) are released by cells as a response to microbial infection. They are best known for their antiviral and immunomodulatory functions. IFNs bind to cell surface receptors which then initiate a signalling cascade inside the cell, ultima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044f75d6b757ea8799f3ca22d1651d64
https://doi.org/10.1016/j.cyto.2015.08.122
https://doi.org/10.1016/j.cyto.2015.08.122