Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Christin M Hong"'
Autor:
Yunlu Xue, Sean K Wang, Parimal Rana, Emma R West, Christin M Hong, Helian Feng, David M Wu, Constance L Cepko
Publikováno v:
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity visi
Externí odkaz:
https://doaj.org/article/1d602be0a51c44ae81306f4e01339bb2
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 376-386 (2020)
Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lac
Externí odkaz:
https://doaj.org/article/a01a18cf1729403a9a933268be62fc27
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 376-386 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Gene therapy with recombinant adeno-associated viral (AAV) vectors is a promising modality for the treatment of a variety of human diseases. Nonetheless, there remain significant gaps in our understanding of AAV vector biology, due in part to the lac
Publikováno v:
Proceedings of the National Academy of Sciences. 116:10140-10149
Retinitis pigmentosa (RP) is a disease that initially presents as night blindness due to genetic deficits in the rod photoreceptors of the retina. Rods then die, causing dysfunction and death of cone photoreceptors, the cell type that mediates high a
Author response: AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa
Autor:
Christin M Hong, David M. Wu, Constance L. Cepko, Parimal Rana, Sean K. Wang, Yunlu Xue, Emma R. West, Helian Feng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd161d6c4c49992d2f318dcd8bff2a6
https://doi.org/10.7554/elife.66240.sa2
https://doi.org/10.7554/elife.66240.sa2
Autor:
Parimal Rana, Sean K. Wang, Constance L. Cepko, Emma R. West, David M. Wu, Helian Feng, Yunlu Xue, Christin M Hong
Retinitis pigmentosa (RP) is an inherited retinal disease, affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high acuity vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6905731e1ae3f69ba04a8637b06eb5e
https://doi.org/10.1101/2021.01.27.428411
https://doi.org/10.1101/2021.01.27.428411
Autor:
Emma R. West, Parimal Rana, Sean K. Wang, Helian Feng, Constance L. Cepko, David M. Wu, Yunlu Xue, Christin M Hong
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) is an inherited retinal disease affecting >20 million people worldwide. Loss of daylight vision typically occurs due to the dysfunction/loss of cone photoreceptors, the cell type that initiates our color and high-acuity visi
Autor:
Joyce Chen, Christin M. Hong, Dinesh S. Rao, David Baltimore, Dong Sung An, Steven M Nguyen, Yong Ouyang, Alejandro B. Balazs
Publikováno v:
Nature medicine
Nature medicine, vol 20, iss 3
Nature medicine, vol 20, iss 3
The vast majority of new HIV infections result from relatively inefficient transmission of the virus across mucosal surfaces during sexual intercourse. A consequence of this inefficiency is that small numbers of transmitted founder viruses initiate m
Autor:
Christin M. Hong, Cailin Deal, David Baltimore, Yong Ouyang, Alejandro B. Balazs, Dong Sung An
Publikováno v:
AIDS Research and Human Retroviruses. 30:A16-A17
Recent reports in humanized mice and monkeys have found that broadly neutralizing antibodies (bNAbs) can suppress the replication of laboratory strains of HIV and SHIV while bNAb concentration remains high. Vectored ImmunoProphylaxis (VIP) results in
Publikováno v:
Nature biotechnology. 31(7)
Neutralizing antibodies that target epitopes conserved among many strains of influenza virus have been recently isolated from humans. Here we demonstrate that adeno-associated viruses (AAV) encoding two such broadly neutralizing antibodies are protec