Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Christin Gumpp"'
Autor:
Basil T Thommen, Jerzy M Dziekan, Fiona Achcar, Seth Tjia, Armin Passecker, Katarzyna Buczak, Christin Gumpp, Alexander Schmidt, Matthias Rottmann, Christof Grüring, Matthias Marti, Zbynek Bozdech, Nicolas MB Brancucci
Publikováno v:
eLife, Vol 12 (2023)
Plasmodium falciparum accounts for the majority of over 600,000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative modes of action is thus undoubted. The FK506-bind
Externí odkaz:
https://doaj.org/article/5679a4b7ec0b409c88f8c92133fec9a0
Autor:
Basil T. Thommen, Jerzy M. Dziekan, Fiona Achcar, Seth Tjia, Armin Passecker, Katarzyna Buczak, Christin Gumpp, Alexander Schmidt, Matthias Rottmann, Christof Grüring, Matthias Marti, Zbynek Bozdech, Nicolas M. B. Brancucci
Plasmodium falciparum accounts for the majority of over 600’000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative modes of action is thus undoubted. The FK506-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c6df9105f3d6b19a53f11295a51ab4
https://doi.org/10.7554/elife.86975
https://doi.org/10.7554/elife.86975
Autor:
Basil T. Thommen, Jerzy M. Dziekan, Fiona Achcar, Seth Tjia, Armin Passecker, Katarzyna Buczak, Christin Gumpp, Alexander Schmidt, Matthias Rottmann, Christof Grüring, Matthias Marti, Zbynek Bozdech, Nicolas M. B. Brancucci
Plasmodium falciparumaccounts for the majority of over 600’000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative modes of action is thus undoubted. The FK506-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3930304a0e385d81eb98f155cb59356b
https://doi.org/10.1101/2022.12.09.519720
https://doi.org/10.1101/2022.12.09.519720
Autor:
Sebastian G, Wicha, Annabelle, Walz, Mohammed H, Cherkaoui-Rbati, Nils, Bundgaard, Karsten, Kuritz, Christin, Gumpp, Nathalie, Gobeau, Jörg, Möhrle, Matthias, Rottmann, Claudia, Demarta-Gatsi
Publikováno v:
Antimicrobial agents and chemotherapy. 66(11)
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Autor:
Georges F R, Radohery, Annabelle, Walz, Christin, Gumpp, Mohammed H, Cherkaoui-Rbati, Nathalie, Gobeau, Jeremy, Gower, Miles P, Davenport, Matthias, Rottmann, James S, McCarthy, Jörg J, Möhrle, Maria, Rebelo, Claudia, Demarta-Gatsi, David S, Khoury
Publikováno v:
Antimicrobial agents and chemotherapy. 66(7)
The rate at which parasitemia declines in a host after treatment with an antimalarial drug is a major metric for assessment of antimalarial drug activity in preclinical models and in early clinical trials. However, this metric does not distinguish be
Autor:
Sebastian G. Wicha, Annabelle Walz, Mohammed H. Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi
The development and spread of drug resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4207f08f0ab8650dc4f78b285258737
https://doi.org/10.1101/2022.04.19.488858
https://doi.org/10.1101/2022.04.19.488858
Autor:
Sebastian G. Wicha, Annabelle Walz, Mohammed H. Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51aa13cc6c34f92d37762808071bd8b0
Autor:
Georges F. R. Radohery, Annabelle Walz, Christin Gumpp, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Jeremy Gower, Miles P. Davenport, Matthias Rottmann, James S. McCarthy, Jörg J. Möhrle, Maria Rebelo, Claudia Demarta-Gatsi, David S. Khoury
The rate at which parasitemia declines in a host after treatment with an antimalarial drug is a major metric for assessment of antimalarial drug activity in preclinical models and in early clinical trials. However, this metric does not distinguish be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1814a75e43518a8968e14d2be8b932b
https://edoc.unibas.ch/90789/
https://edoc.unibas.ch/90789/
Autor:
Thomas Spangenberg, Matthias Rottmann, Beatrice Greco, Xiaoyan Yin, Satish K. Dhingra, Christin Gumpp, Claude Oeuvray, Lassina Badolo, Brian Jonat, David A. Fidock, Marla J. Giddins
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimalarial drug resistance in the Plasmodium falciparum parasite poses a constant challenge for drug development. To mitigate this risk, new antimalarial medicines should be developed as fixed-dose combinations. Assessing the pharmacodynamic intera