Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christin, Bauer"'
Autor:
Jonathan D. Taylor, Nathalie Barrett, Sergio Martinez Cuesta, Katelyn Cassidy, Fiona Pachl, James Dodgson, Radhika Patel, Tuula M. Eriksson, Aidan Riley, Matthew Burrell, Christin Bauer, D. Gareth Rees, Raffaello Cimbro, Andrew X. Zhang, Ralph R. Minter, James Hunt, Sandrine Legg
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Proteins can be targeted for degradation by engineering biomolecules that direct them to the eukaryotic ubiquitination machinery. For instance, the fusion of an E3 ubiquitin ligase to a suitable target binding domain creates a ‘biological
Externí odkaz:
https://doaj.org/article/82c3864e38134c29b42485f93454e6e6
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83942 (2013)
p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila res
Externí odkaz:
https://doaj.org/article/44797b1d2c3a4383bf6e44afe76cad6c
Autor:
Tong, Zhang, Christin, Bauer, Alice C, Newman, Alejandro Huerta, Uribe, Dimitris, Athineos, Karen, Blyth, Oliver D K, Maddocks
Publikováno v:
Nature metabolism. 2(10)
Cancer cells have high demands for non-essential amino acids (NEAAs), which are precursors for anabolic and antioxidant pathways that support cell survival and proliferation. It is well-established that cancer cells consume the NEAA cysteine, and tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bda1549cc2619a7fa8247d45ac98e398
https://pubmed.ncbi.nlm.nih.gov/32747794
https://pubmed.ncbi.nlm.nih.gov/32747794
Autor:
Katharina Christin Bauer, Frank Hämmerling, Jörg Kittelmann, Cathrin Dürr, Jürgen Hubbuch, Fabian Görlich
Publikováno v:
Biotechnology and Bioengineering. 114:821-831
Information about protein-protein interactions provides valuable knowledge about the phase behavior of protein solutions during the biopharmaceutical production process. Up to date it is possible to capture their overall impact by an experimentally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d44ef7f2e4b32c2b29c481c27c9f347
https://doi.org/10.1002/bit.26210
https://doi.org/10.1002/bit.26210
Autor:
Mathias Göbel, Marie-Therese Schermeyer, Katharina Christin Bauer, Marie-Luise Schwab, Jürgen Hubbuch
Publikováno v:
International Journal of Pharmaceutics. 511:276-287
The colloidal stability of a protein solution during downstream processing, formulation, and storage is a key issue for the biopharmaceutical production process. Thus, knowledge about colloidal solution characteristics, such as the tendency to form a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a276007ad5e83495ccc2d64bbd126
https://doi.org/10.1016/j.ijpharm.2016.07.007
https://doi.org/10.1016/j.ijpharm.2016.07.007
Publikováno v:
Cell Cycle
Bursicon is the main regulator of post molting and post eclosion processes during arthropod development. The active Bursicon hormone is a heterodimer of Burs-α and Burs-β. However, adult midguts express Burs-α to regulate the intestinal stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e1c39d033716aa271b93d44b52796e
https://doi.org/10.1080/15384101.2015.1121334
https://doi.org/10.1080/15384101.2015.1121334
Autor:
Claude Oelschlaeger, Jürgen Hubbuch, Katharina Christin Bauer, Marie-Therese Schermeyer, Heike Sigloch
Publikováno v:
Biotechnology and Bioengineering. 113:576-587
This study aims at defining rheological parameters for the characterization of highly concentrated protein solutions. As a basis for comparing rheological behavior with protein solution characteristics the protein phase behavior of Lysozyme from chic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3020965162a63d1f596d6272753ec4f4
https://doi.org/10.1002/bit.25834
https://doi.org/10.1002/bit.25834
Publikováno v:
Biotechnology and Bioengineering. 112:2485-2494
The surface hydrophobicity of a protein is an important factor for its interactions in solution and thus the outcome of its production process. Yet most of the methods are not able to evaluate the influence of these hydrophobic interactions under nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9ed887fa491b9748d25338efb3ec20
https://doi.org/10.1002/bit.25677
https://doi.org/10.1002/bit.25677
Publikováno v:
International journal of pharmaceutics. 516(1-2)
In concentrated protein solutions attractive protein interactions may not only cause the formation of undesired aggregates but also of gel-like networks with elevated viscosity. To guarantee stable biopharmaceutical processes and safe formulations, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c33305d2e4d6c636513669182a89f6
https://pubmed.ncbi.nlm.nih.gov/27836754
https://pubmed.ncbi.nlm.nih.gov/27836754
Autor:
Katharina Christin, Bauer, Frank, Hämmerling, Jörg, Kittelmann, Cathrin, Dürr, Fabian, Görlich, Jürgen, Hubbuch
Publikováno v:
Biotechnology and bioengineering. 114(4)
Information about protein-protein interactions provides valuable knowledge about the phase behavior of protein solutions during the biopharmaceutical production process. Up to date it is possible to capture their overall impact by an experimentally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6da0a6cabf91179ca94b4edf760bc991
https://pubmed.ncbi.nlm.nih.gov/27801503
https://pubmed.ncbi.nlm.nih.gov/27801503