Výsledky vyhledávání - "Christie P. Fanton"

Supplementary Data from PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies

Figures S1, S2, s3, S4, Table S1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657c2118ddc53bb94cc549cd76abf99c
https://doi.org/10.1158/1535-7163.22521895.v1

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Data from PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies

The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast, esophagus, lung, and upper aerodigestive system. PCA062 is a P-cadherin specific antibody–dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42af133f07879ce825ff1f600618e03a
https://doi.org/10.1158/1535-7163.c.6543214.v1

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Table S2 from PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies

Cell line sensitivity table

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a00bb2e2018e033b09c776799bf3e3
https://doi.org/10.1158/1535-7163.22521889.v1

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Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts

Autor: Kathryn A. Lester, Christie P. Fanton, Russell O. Pieper

Publikováno v: Nucleic Acids Research. 27:3229-3235

Growth constraint of bacterial and human cells has been shown to trigger genetic mutation. We questioned whether growth constraint might also trigger epigenetic mutation in the form of CpG island methylation. Logarithmically growing normal human fibr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d05ad6bb2e4fc1ffbafc23ac92235e
https://doi.org/10.1093/nar/27.15.3229

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Induction of tubulogenesis in telomerase-immortalized human microvascular endothelial cells by glioblastoma cells

Autor: Eleni Venetsanakos, Serguei R. Romanov, Martin McMahon, Thea D. Tlsty, Amer M. Mirza, Christie P. Fanton

Publikováno v: Experimental cell research, vol 273, iss 1

To facilitate the study of human endothelial cells we have used a replication defective retrovirus encoding the catalytic subunit of telomerase (hTERT) to derive populations of telomerase-immortalized human microvascular endothelial (TIME) cells. Whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af649a3d3a0ba90e8de4656e002cc5cf
https://escholarship.org/uc/item/2dk07928

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Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation

Autor: Russell O. Pieper, Christie P. Fanton, Martin McMahon

Publikováno v: The Journal of biological chemistry. 276(22)

Normal human fibroblasts have been shown to undergo a p16(Ink4a)-associated senescence-like growth arrest in response to sustained activation of the Ras/Raf/MEK/ERK pathway. We noted a similar p16(Ink4a)-associated, senescence-like arrest in normal h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fae6b77490f2371d82ecb87e5cbec1
https://pubmed.ncbi.nlm.nih.gov/11278920

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Akademický článek

Development of a Screening Assay for Surrogate Markers of Chk1 Inhibitor-Induced Cell Cycle Release.

Autor: Christie P. Fanton

Publikováno v: Journal of Biomolecular Screening; Oct2006, Vol. 11 Issue 7, p792-806, 15p

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