Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christie M. Lew"'
Autor:
Junji Yodoi, Viviana I. Pérez, Wilson C. Fok, Holly Van Remmen, Asish R. Chaudhuri, Kaoru Tominaga, Lisa A. Cortez, Arlan Richardson, Christie M. Lew, Yuji Ikeno, Celeste R. Webb, Yiqiang Zhang, Dean P. Jones, Shuko Lee, Gene B. Hubbard, Wenbo Qi, Alex Bokov, Marisela Rodriguez
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. :1286-1299
We examined the effects of increased levels of thioredoxin 1 (Trx1) on resistance to oxidative stress and aging in transgenic mice overexpressing Trx1 [Tg(TRX1)(+/0)]. The Tg(TRX1)(+/0) mice showed significantly higher Trx1 protein levels in all the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaec96b95923f60c60c6e3f55a5c53bb
https://doi.org/10.1093/gerona/glr125
https://doi.org/10.1093/gerona/glr125
Autor:
Arlan Richardson, Celeste R. Webb, Viviana I. Pérez, Marisela Rodriguez, Yuhong Liu, Yuji Ikeno, Christie M. Lew, Wenbo Qi, Yan Li, Asish R. Chaudhuri, Holly Van Remmen, Lisa A. Cortez
Publikováno v:
Free Radical Biology and Medicine. 44:882-892
The mitochondrial form of thioredoxin, thioredoxin 2 (Txn2), plays an important role in redox control and protection against ROS-induced mitochondrial damage. To evaluate the effect of reduced levels of Txn2 in vivo, we measured oxidative damage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a8f3b6630165c5955876fde9d16bdf
https://doi.org/10.1016/j.freeradbiomed.2007.11.018
https://doi.org/10.1016/j.freeradbiomed.2007.11.018
Publikováno v:
AGE. 28:163-171
Rodent models are an invaluable resource for studying the mechanism of mammalian aging. In recent years, the availability of transgenic and knockout mouse models has facilitated the study of potential mechanisms of aging. Since 1996, aging studies wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb7e0d60a11510e44903922682347fe
https://doi.org/10.1007/s11357-006-9007-7
https://doi.org/10.1007/s11357-006-9007-7