Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christie L. Funckes-Shippy"'
Autor:
Barbara A. Schweitzer, Atli Thorarensen, Michael S. Davies, Steve R. Turner, Matthew James Pelc, James R. Kiefer, Brenda L. Case, Christie L. Funckes-Shippy, Jacqueline E. Day, Fengmei Hua, Dice Tom, William M. Abraham, Bradley E. Neal, John I. Trujillo, Joseph B. Moon, Blake Tanisha Danielle Rowe, Wei Huang, Craig D. Wegner, Dean Welsch, Chris P. Carron, Anup Zutshi, Bruce C. Hamper, Chad J. Warren, Rhonda S. Woerndle, Christine M. Kornmeier, Vickie M. Dilworth, Melanie L. Williams, Martin E. Dowty, Olson Kirk Lang, Melissa R. Radabaugh, Becky L. Hood, Jerry Z. Yang, Douglas C. Rohrer, Gina M. Jerome, Christine P. Bono
Publikováno v:
ACS Medicinal Chemistry Letters. 1:59-63
Hematopoietic prostaglandin D synthase (HPGDS) is primarly expressed in mast cells, antigen-presenting cells, and Th-2 cells. HPGDS converts PGH2 into PGD2, a mediator thought to play a pivotal role in airway allergy and inflammatory processes. In th
Autor:
Christie L Funckes-Shippy, Iwona S Spath, Debra S Garner, W. Rachel Duan, Eric A G Blomme, Steven D Williams
Publikováno v:
The Journal of Pathology. 199:221-228
The terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end labelling (TUNEL) technique has been extensively used for the detection and quantification of apoptosis in histological tissue sections. However, the interpretation and specificit
Autor:
Shashi K. Ramaiah, Christie L. Funckes-Shippy, Nandini Kishore, Xiong Li, James D. Warner, Jeffrey L. Hirsch, Michael I. Jesson, Dale L. Morris, Debra M. Meyer, Matthew J. Saabye, Mollisa M. Elrick, Cindy J. Gross, Jennifer L Barks, Martin E. Dowty
Publikováno v:
Journal of Inflammation, Vol 7, Iss 1, p 41 (2010)
Journal of Inflammation (London, England)
Journal of Inflammation (London, England)
Background The Janus kinase (JAK) family of tyrosine kinases includes JAK1, JAK2, JAK3 and TYK2, and is required for signaling through Type I and Type II cytokine receptors. CP-690,550 is a potent and selective JAK inhibitor currently in clinical tri
Autor:
W. Rodney Mathews, Olga V. Nemirovskiy, Stephen J. Mnich, Debra M. Meyer, Melissa R. Radabaugh, T. Sunyer, Christie L. Funckes-Shippy, Poonam Aggarwal, Thomas P. Misko
Publikováno v:
Nitric oxide : biology and chemistry. 20(3)
The contribution of inducible nitric oxide synthase (iNOS) to oxidative/nitrative stress is well-documented in inflammation, but difficult to quantify. Using a novel, recently developed assay for 3-nitrotyrosine (3-NT), we characterized iNOS activity
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 84(17)
The suppressor T-cell hybridoma 1556A2.1 can be induced by the monoclonal L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT)-specific suppressor inducer 372B3.5 and soluble GAT to synthesize a disulfide-linked heterodimeric protein (GAT-TsF2), which di