Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Christie L. Doxsee"'
Autor:
John P. Vasilakos, Tony R. Riter, Randolph J. Noelle, Richard J. Barth, Ross M. Kedl, Christie L. Doxsee, Cory L. Ahonen, William F. Wade, Sean M. McGurran
Publikováno v:
The Journal of Experimental Medicine
Toll-like receptors are important in the activation of innate immunity, and CD40 is a molecule critical for many T and B cell responses. Whereas agonists for either pathway have been used as vaccine adjuvants, we show that a combination of Toll-like
Autor:
John P. Vasilakos, Ross M. Kedl, Tony R. Riter, Christie L. Doxsee, Shelia J. Gibson, Michael J. Reiter
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 171(3)
IL-12 and TNF-α production by dendritic cells (DCs) is a critical step in the initiation of local inflammation and adaptive immune responses. We show in this study that a small molecule immune response modifier that is a Toll-like receptor 7 (TLR7)