Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Christie J. Kang"'
Autor:
L. Jackson Roberts, James West, Anna R. Hemnes, Amy T. Shah, Robert A. Egnatchik, H. James Ford, Thong Luong, Melissa C. Skala, Eric D. Austin, Wassim H. Fares, Joshua P. Fessel, Erik B. Hysinger, Emily G. Kocurek, Shijun Zhu, Ken Monahan, Thuy T. Nguyen, Christie J. Kang, Evan L. Brittain, Jamey D. Young
Publikováno v:
Pulmonary Circulation
Pulmonary arterial hypertension (PAH) is increasingly recognized as a systemic disease driven by alteration in the normal functioning of multiple metabolic pathways affecting all of the major carbon substrates, including amino acids. We found that hu
Autor:
Christie J. Kang, Xinping Chen, Jennifer Johnson, Santhi Gladson, Andrea L. Frump, Thomas R. Blackwell, James E. Loyd, Joshua P. Fessel, James West, Anna R. Hemnes, Eric D. Austin
Publikováno v:
Pulmonary Circulation. 3:564-577
The majority of heritable pulmonary arterial hypertension (HPAH) cases are associated with mutations in bone morphogenetic protein receptor type 2 (BMPR2). BMPR2 mutation carries about a 20% lifetime risk of PAH development, but penetrance is approxi
Autor:
Joshua P. Fessel, Niki Penner, Charles R. Flynn, David H. Wasserman, Santhi Gladson, James West, Anna R. Hemnes, Christie J. Kang, Linda Robinson
Publikováno v:
American journal of respiratory cell and molecular biology. 49(5)
Pulmonary arterial hypertension (PAH) has been associated with a number of different but interrelated pathogenic mechanisms. Metabolic and oxidative stresses have been shown to play important pathogenic roles in a variety of model systems. However, m