Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christie Brannock"'
Autor:
Irina N. Krasnova, Maria Carla Gerra, Donna Walther, Subramaniam Jayanthi, Bruce Ladenheim, Michael T. McCoy, Christie Brannock, Jean Lud Cadet
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Methamphetamine addiction is mimicked in rats that self-administer the drug. However, these self-administration (SA) models do not include adverse consequences that are necessary to reach a diagnosis of addiction in humans. Herein, we measur
Externí odkaz:
https://doaj.org/article/15ada644cfec422ba706a3e1b266905a
Autor:
Irina N. Krasnova, Margarit Chiflikyan, Zuzana Justinova, Michael T. McCoy, Bruce Ladenheim, Subramaniam Jayanthi, Cynthia Quintero, Christie Brannock, Chanel Barnes, Jordan E. Adair, Elin Lehrmann, Firas H. Kobeissy, Mark S. Gold, Kevin G. Becker, Steven R. Goldberg, Jean Lud Cadet
Publikováno v:
Neurobiology of Disease, Vol 58, Iss , Pp 132-143 (2013)
Neuroplastic changes in the dorsal striatum participate in the transition from casual to habitual drug use and might play a critical role in the development of methamphetamine (METH) addiction. We examined the influence of METH self-administration on
Externí odkaz:
https://doaj.org/article/3bef33c68d5d46259f353195dcbcc6e1
Autor:
Jean Lud Cadet, Christie Brannock, Bruce Ladenheim, Michael T McCoy, Irina N Krasnova, Elin Lehrmann, Kevin G Becker, Subramaniam Jayanthi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84665 (2014)
Methamphetamine (METH) is a widely abused amphetamine analog. Few studies have investigated the molecular effects of METH exposure in adult animals. Herein, we determined the consequences of an injection of METH (10 mg/kg) on transcriptional effects
Externí odkaz:
https://doaj.org/article/1b287a5ef6df4b27aff20ae86bdc4074
Autor:
Tracey A Martin, Subramaniam Jayanthi, Michael T McCoy, Christie Brannock, Bruce Ladenheim, Tiffany Garrett, Elin Lehrmann, Kevin G Becker, Jean Lud Cadet
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34236 (2012)
Methamphetamine (METH) addiction is associated with several neuropsychiatric symptoms. Little is known about the effects of METH on gene expression and epigenetic modifications in the rat nucleus accumbens (NAC). Our study investigated the effects of
Externí odkaz:
https://doaj.org/article/a2868a5a42aa46d389ebcf1b8fe39c70
Autor:
Jean Lud Cadet, Christie Brannock, Bruce Ladenheim, Michael T. McCoy, Genevieve Beauvais, Amber B. Hodges, Elin Lehrmann, William H. Wood, Kevin G. Becker, Irina N. Krasnova
Publikováno v:
Dose-Response, Vol 9 (2011)
Methamphetamine (METH) is a toxic drug of abuse, which can cause significant decreases in the levels of monoamines in various brain regions. However, animals treated with progressively increasing doses of METH over several weeks are protected against
Externí odkaz:
https://doaj.org/article/da83c2a9f4c04ae484da2cb5d2d54f83
Autor:
Jean Lud Cadet, Christie Brannock, Irina N Krasnova, Bruce Ladenheim, Michael T McCoy, Jenny Chou, Elin Lehrmann, William H Wood, Kevin G Becker, Yun Wang
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15643 (2010)
Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle are used extensively as a model of Parkinson's disease. The present experiments sought to identify genes that were affected in the dopamine (DA)-denervated striatum after 6-h
Externí odkaz:
https://doaj.org/article/e11e909f60e946068f603bde0da19702
Autor:
Christie Brannock, Jennifer R. Schroeder, Subramaniam Jayanthi, Jean Lud Cadet, Atul P. Daiwile, Bruce Ladenheim, Michael T. McCoy
Publikováno v:
International Journal of Neuropsychopharmacology. 22:710-723
BackgroundMethamphetamine (METH) use disorder is prevalent worldwide. There are reports of sex differences in quantities of drug used and relapses to drug use among individuals with METH use disorder. However, the molecular neurobiology of these pote
Autor:
Irina N. Krasnova, Richard S. Lee, Jean Lud Cadet, Bruce Ladenheim, Christie Brannock, Mehdi Pirooznia, Donna Walther, Subramaniam Jayanthi, Arthur Godino, Michael T. McCoy
Publikováno v:
Mol Psychiatry
Epigenetic consequences of exposure to psychostimulants are substantial but the relationship of these changes to compulsive drug taking and abstinence is not clear. Here, we used a paradigm that helped to segregate rats that reduce or stop their meth
Autor:
Oscar V. Torres, Jean Lud Cadet, Bruce Ladenheim, Ingrid Tulloch, Christie Brannock, Michael T. McCoy, Irina N. Krasnova, Subramaniam Jayanthi
Publikováno v:
Scientific Reports
Methamphetamine (METH) produces increases in the expression of immediate early genes (IEGs) and of histone deacetylase 2 (HDAC2) in the rat nucleus accumbens (NAc). Here, we tested whether HDAC2 deletion influenced the effects of METH on IEG expressi
Autor:
Christie Brannock, Jean Lud Cadet
Publikováno v:
Neurochemistry International. 32:117-131
Oxygen is an essential element for normal life. However, reactive oxygen species (ROS) can also participate in deleterious reactions that can affect lipid, protein, and nucleic acid. Normal physiological function thus depends on a balance between the