Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes.

Autor: Farrell, Kurt, Humphrey, Jack, Chang, Timothy, Zhao, Yi, Leung, Yuk Yee, Kuksa, Pavel P., Patil, Vishakha, Lee, Wan-Ping, Kuzma, Amanda B., Valladares, Otto, Cantwell, Laura B., Wang, Hui, Ravi, Ashvin, De Sanctis, Claudia, Han, Natalia, Christie, Thomas D., Afzal, Robina, Kandoi, Shrishtee, Whitney, Kristen, Krassner, Margaret M.

Publikováno v: Nature Communications; 11/14/2024, Vol. 15 Issue 1, p1-17, 17p

Spatial proteomics of hippocampal subfield‐specific pathology in Alzheimer's disease and primary age‐related tauopathy.

Autor: Walker, Jamie M., Orr, Miranda E., Orr, Timothy C., Thorn, Emma L., Christie, Thomas D., Yokoda, Raquel T., Vij, Meenakshi, Ehrenberg, Alexander J., Marx, Gabriel A., McKenzie, Andrew T., Kauffman, Justin, Selmanovic, Enna, Wisniewski, Thomas, Drummond, Eleanor, White, Charles L., Crary, John F., Farrell, Kurt, Kautz, Tiffany F., Daoud, Elena V., Richardson, Timothy E.

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Feb2024, Vol. 20 Issue 2, p783-797, 15p

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy.

Autor: Walker JM; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA., Orr ME; Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.; Sticht Center for Healthy Aging and Alzheimer's Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.; Salisbury VA Medical Center, Salisbury, North Carolina, USA., Orr TC; Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.; Department of Healthcare Innovations, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Thorn EL; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Christie TD; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Yokoda RT; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Vij M; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ehrenberg AJ; Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, USA.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, USA.; Innovative Genomics Institute, University of California, Berkeley, Berkeley, California, USA., Marx GA; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Ronal M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., McKenzie AT; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Ronal M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Kauffman J; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Ronal M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Selmanovic E; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Wisniewski T; Department of Pathology, New York University Grossman School of Medicine, New York, New York, USA.; Department of Psychiatry, New York University Grossman School of Medicine, New York, New York, USA.; Center for Cognitive Neurology, Department of Neurology, New York University Grossman School of Medicine, New York, New York, USA., Drummond E; Brain & Mind Center and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., White CL 3rd; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Crary JF; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Ronal M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Farrell K; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Artificial Intelligence & Human Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Ronal M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Kautz TF; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA., Daoud EV; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Richardson TE; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Neuropathology Brain Bank & Research CoRE, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Feb; Vol. 20 (2), pp. 783-797. Date of Electronic Publication: 2023 Sep 30.