Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Christie, Lance"'
Autor:
Mark B. Anderson, David R. Luthin, Rosemary Castillo, Kenna Anderes, Eugenia A. Iatsimirskaia, John M. May, K. Eric Milgram, Ved P. Pathak, Vazir Haresh N, Margaret L. Gregory, Christie Lance Christopher
Publikováno v:
Pharmaceutical Research. 19:202-208
Purpose. The expression of cytochrome P450 enzymes (CYPs) in animals and humans is under complex hormonal regulation. Chronic treatment with drugs that alter sex hormone levels such as GnRH receptor agonists or antagonists may affect the expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0af2e5360bc267ffe8b8e87d380f1d
https://doi.org/10.1023/a:1014281018271
https://doi.org/10.1023/a:1014281018271
Autor:
Selness, Shaun R., Devraj, Rajesh V., Devadas, Balekudru, Walker, John K., Boehm, Terri L., Durley, Richard C., Shieh, Huey, Xing, Li, Rucker, Paul V., Jerome, Kevin D., Benson, Alan G., Marrufo, Laura D., Madsen, Heather M., Hitchcock, Jeff, Owen, Tom J., Christie, Lance, Promo, Michele A., Hickory, Brian S., Alvira, Edgardo, Naing, Win, Blevis-Bal, Radhika, Messing, Dean, Yang, Jerry, Mao, Michael K., Yalamanchili, Gopi, Vonder Embse, Richard, Hirsch, Jeffrey, Saabye, Matthew, Bonar, Sheri, Webb, Elizabeth, Anderson, Gary, Monahan, Joseph B.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 July 2011 21(13):4066-4071
Autor:
Selness, Shaun R., Boehm, Terri L., Walker, John K., Devadas, Balekudru, Durley, Richard C., Kurumbail, Ravi, Shieh, Huey, Xing, Li, Hepperle, Michael, Rucker, Paul V., Jerome, Kevin D., Benson, Alan G., Marrufo, Laura D., Madsen, Heather M., Hitchcock, Jeff, Owen, Tom J., Christie, Lance, Promo, Michele A., Hickory, Brian S., Alvira, Edgardo, Naing, Win, Blevis-Bal, Radhika, Devraj, Rajesh V., Messing, Dean, Schindler, John F., Hirsch, Jeffrey, Saabye, Matthew, Bonar, Sheri, Webb, Elizabeth, Anderson, Gary, Monahan, Joseph B.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 July 2011 21(13):4059-4065
Autor:
Mary Hess, Simon Bailey, Christie Lance Christopher, Jack H. Kellum, Brett H. Simmons, Guy A. McClellan, Paul S. Humphries, Kathleen M. Ogilvie, Jonathon V. Almaden, Skalitzky Donald James, Young Ha Kim, Shaoxian Sun, Thomas J. Carlson, David M. Wilhite, James D. Fraser, Zehnder Luke Raymond, Sandra J. Barnum, Quyen-Quyen T. Do
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(23)
A series of novel pyridine-3-propanoic acids was synthesized. A structure–activity relationship study of these compounds led to the identification of potent dual PPARα/γ agonists with varied isoform selectivity. Based on the results of efficacy s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f05a304dd45bde0ff8512da4c99c87
https://pubmed.ncbi.nlm.nih.gov/16973358
https://pubmed.ncbi.nlm.nih.gov/16973358
Autor:
Christie Lance Christopher, Mary A. Castro, Margaret L. Gregory, Rosemary Castillo, David Robert Luthin, Kenna Anderes, Ved P. Pathak, Qiang Ye, John M. May, Vazir Haresh N, Karen D. Nared-Hood, Paderes Genevieve Deguzman, Mark B. Anderson, Eugenia Kraynov
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 305(2)
Gonadotropin-releasing hormone (GnRH) receptor antagonists have potential in treating numerous hormone-dependent pathologies including cancers of the prostate, breast, and ovary, endometriosis, and fertility disorders. An unmet clinical need exists f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a70f2dc47519c5fe5e21ba064852b2
https://pubmed.ncbi.nlm.nih.gov/12606616
https://pubmed.ncbi.nlm.nih.gov/12606616
Autor:
Li Haitao, Eileen Valenzuela Tompkins, David R. Luthin, Vazir Haresh N, Christie Lance Christopher, Paderes Genevieve Deguzman, John M. May, Yufeng Hong, Mark B. Anderson, Mary A. Castro, Karen D. Nared-Hood, Ved P. Pathak
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(23)
A novel series of non-peptide derivatives 1, 14, and 15 that bind with high affinity to the human GnRH receptors is discussed. The discovery was made from screening our in-house libraries that contained the active structure 2 along with a trace amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eac317a5ad6ae4e411b91958995d8a2
https://pubmed.ncbi.nlm.nih.gov/12419385
https://pubmed.ncbi.nlm.nih.gov/12419385
Autor:
Selness, Shaun R., Devraj, Rajesh V., Monahan, Joseph B., Boehm, Terri L., Walker, John K., Devadas, Balekudru, Durley, Richard C., Kurumbail, Ravi, Shieh, Huey, Xing, Li, Hepperle, Michael, Rucker, Paul V., Jerome, Kevin D., Benson, Alan G., Marrufo, Laura D., Madsen, Heather M., Hitchcock, Jeff, Owen, Tom J., Christie, Lance, Promo, Michele A., Hickory, Brian S., Alvira, Edgardo, Naing, Win, Blevis-Bal, Radhika
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2009 19(20):5851-5856
Autor:
Humphries, Paul S., Bailey, Simon, Almaden, Jonathon V., Barnum, Sandra J., Carlson, Thomas J., Christie, Lance C., Do, Quyen-Quyen T., Fraser, James D., Hess, Mary, Kellum, Jack, Kim, Young H., McClellan, Guy A., Ogilvie, Kathleen M., Simmons, Brett H., Skalitzky, Donald, Sun, Shaoxian, Wilhite, David, Zehnder, Luke R.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2006 16(23):6120-6123
Autor:
Ved P. Pathak, Christie Lance Christopher, Mark C. Guzman, Mark B. Anderson, Haitao Li, Ranjan Jagath Rajapakse, Alex K. Rabinovich, Stella Tsank, Wayne D. Kornreich, Thomas Goetzen, Larry K. Truesdale, Haresh N. Vazir, Scott A. Shackelford, Martha A. Hananel
Publikováno v:
The Journal of Organic Chemistry. 68:2986-2986
A new one-pot nitration employing tetramethylammonium nitrate and trifluoromethanesulfonic anhydride in dichloromethane to provide a ready source of the nitronium triflate nitrating agent is presented. Rapid and selective nitration with a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d895ef6e3b62ac1f548e4d22863af9
https://doi.org/10.1021/jo039925y
https://doi.org/10.1021/jo039925y
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