Výsledky vyhledávání - "Christiano M.V. Barbosa"

Gomesin acts in the immune system and promotes myeloid differentiation and monocyte/macrophage activation in mouse

Autor: Edgar J. Paredes-Gamero, Amanda Nogueira-Pedro, Christiano M.V. Barbosa, Marcus V. Buri, Carol C. Dias, Antonio Miranda, Antonio C. Ribeiro-Filho

Publikováno v: Peptides. 85:41-45

Due to the cytotoxic effect of antimicrobial peptides (AMP) against several microorganism and tumor cells has been proposed their association with the immune system. However, just a few reports have shown this relationship. In this study, mice were t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf13d2772f4d2ea08be36c4ea0ba479c
https://doi.org/10.1016/j.peptides.2016.09.003

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PLCγ2 and PKC Are Important to Myeloid Lineage Commitment Triggered by M-SCF and G-CSF

Autor: Claudia Bincoletto, Alice T. Ferreira, Christiano M.V. Barbosa, Edgar J. Paredes-Gamero, Carlos Castilho Barros

Publikováno v: Journal of Cellular Biochemistry. 115:42-51

Myeloid differentiation is a complex process whereby mature granulocytes or monocytes/macrophages are derived from a common myeloid progenitor through the coordinated action of hematopoietic cytokines. In this study, we explored the role of the Ca(2+

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::324c34ffbdb8c16f9ae1f391724b4fbc
https://doi.org/10.1002/jcb.24653

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Autophagy inhibited Ehrlich ascitic tumor cells apoptosis induced by the nitrostyrene derivative compounds: Relationship with cytosolic calcium mobilization

Autor: Gustavo J.S. Pereira, Edgar J. Paredes-Gamero, Christiano M.V. Barbosa, Claudia Bincoletto, Andrana K. Calgarotto, Soraya S. Smaili, Hanako Hirata, Mary L.S. Queiroz, Alexandre Bechara

Publikováno v: European Journal of Pharmacology. 678:6-14

Apoptosis induction is often associated with increased autophagy, indicating interplay between these two important cellular events in cell death and survival. In this study, the programmed cell death and autophagy induced by two nitrostyrene derivati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8b4459e7829f3f2822e6e839932d5e
https://doi.org/10.1016/j.ejphar.2011.12.031

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Chlorella vulgaris restores bone marrow cellularity and cytokine production in lead-exposed mice

Autor: Miriam R. Romano, Michelle C. da Rocha, Cristiane Okuda Torello, Claudia Bincoletto, Marcelo Antonio Morgano, Edgar J. Paredes-Gamero, Andrana K. Calgarotto, Mary L.S. Queiroz, Christiano M.V. Barbosa, Julia de Souza Queiroz

Publikováno v: Food and Chemical Toxicology. 49:2934-2941

Chlorella vulgaris (CV) was examined for its modulating effects on the reduction induced by lead (Pb) on the numbers of marrow hematopoietic stem cells (HSCs) (c-Kit(+)Lin(-)), granulocyte-macrophage progenitors (Gr1(+)Mac1(+)) and total bone marrow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0066a8ffef62d114d2bec5532f7fe7c
https://doi.org/10.1016/j.fct.2011.06.056

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Comparative study of autophagy inhibition by 3MA and CQ on Cytarabine‑induced death of leukaemia cells

Autor: Claudia Bincoletto, Caroline Palmeira-dos-Santos, Soraya S. Smaili, Christiano M.V. Barbosa, Gustavo J.S. Pereira, Aron Jurkiewicz

Publikováno v: Journal of cancer research and clinical oncology. 140(6)

As the molecular mechanisms of Cytarabine,one of the most important drugs used in the leukaemia’s treatment, are only partially understood and the role of autophagy on leukaemia development and treatment is only recently being investigated, in this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462c5ac065a16eb72fde0f33c29fed4e
https://pubmed.ncbi.nlm.nih.gov/24659340

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Palladacycle (BPC) antitumour activity against resistant and metastatic cell lines: the relationship with cytosolic calcium mobilisation and cathepsin B activity

Autor: Luis Silva, Soraya S. Smaili, Alexandre Bechara, Daniel M. Garcia, Fabio D. Nascimento, Claudia Bincoletto, Edgar J. Paredes-Gamero, Antonio C. F. Caires, Elaine G. Rodrigues, Christiano M.V. Barbosa, Alisson L. Matsuo

Publikováno v: European journal of medicinal chemistry. 79

The search for new compounds that induce p53-independent apoptosis is the focus of many studies in cancer biology because these compounds could be more specific and would overcome chemotherapy resistance. In this study, we evaluated the in vitro anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cd5f8b557f14a5a3052fe2aefe5570
https://pubmed.ncbi.nlm.nih.gov/24709226

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Hematopoietic stem cell expansion caused by a synthetic fragment of leptin

Autor: Ronaldo C. Araujo, Carol C. Dias, Vani Xavier Oliveira, Frederick Wasinski, Antonio Miranda, Antonio C. Ribeiro-Filho, Amanda Nogueira-Pedro, Edgar J. Paredes-Gamero, Christiano M.V. Barbosa

Publikováno v: Peptides. 50

Leptin is a cytokine that regulates food intake, energy expenditure and hematopoiesis. Based on the tridimensional structure of the human leptin molecule, six fragments have been synthesized, (Ac-Lep23-47-NH2, [LEP1]; Ac-Lep48-71-NH2, [LEP2]; Ac-Lep7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003edaf0ba42cbc430ad1b60cd4b218d
https://pubmed.ncbi.nlm.nih.gov/24090593

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Calcium signaling as a regulator of hematopoiesis

Autor: Christiano M.V. Barbosa, Alice T. Ferreira, Edgar J. Paredes-Gamero

Publikováno v: Frontiers in bioscience (Elite edition). 4(4)

Different extracellular signaling molecules that bind to receptors on the cell membrane use calcium ions for signal transduction. Due to the opening of receptor-operated calcium channels, some cytokine receptors and G-protein coupled receptors induce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe510fefdf11c4cd9e432802ddb9e31
https://pubmed.ncbi.nlm.nih.gov/22201962

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alpha-Tocopherol induces hematopoietic stem/progenitor cell expansion and ERK1/2-mediated differentiation

Autor: Helena Regina Comodo Segreto, Lisandro Lungato, Alice T. Ferreira, Andrea Aparecida de Fátima Souza Moraes, Antonio Miranda, Vania D'Almeida, Edgar J. Paredes-Gamero, Christiano M.V. Barbosa, Amanda Nogueira-Pedro

Publikováno v: Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Tocopherols promote or inhibit growth in different cell types. in the hematopoietic system, the radioprotective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3fe57a42fdf62ef2c0a0c9ae82bb00
http://repositorio.unifesp.br/handle/11600/34261

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Differentiation of hematopoietic stem cell and myeloid populations by ATP is modulated by cytokines

Autor: Alice T. Ferreira, Edgar J. Paredes-Gamero, Christiano M.V. Barbosa, Ronaldo C. Araujo, Amanda Nogueira-Pedro, Antonio Miranda, F Wasinsk, Carlos M. M. P Leon

Publikováno v: Cell Death & Disease

Extracellular nucleotides are emerging as important regulators of inflammation, cell proliferation and differentiation in a variety of tissues, including the hematopoietic system. In this study, the role of ATP was investigated during murine hematopo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e969be19570b837c2fcb361c3aa3ae2d
https://pubmed.ncbi.nlm.nih.gov/21633388

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