Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Christiano, Tanese de Souza"'
Autor:
Zaid Taha, Mathieu Joseph François Crupi, Nouf Alluqmani, Duncan MacKenzie, Sydney Vallati, Jack Timothy Whelan, Faiha Fareez, Akram Alwithenani, Julia Petryk, Andrew Chen, Marcus Mathew Spinelli, Kristy Ng, Judy Sobh, Christiano Tanese de Souza, Priya Rose Bharadwa, Timothy Kit Hin Lee, Dylan Anthony Thomas, Ben Zhen Huang, Omar Kassas, Joanna Poutou, Victoria Heather Gilchrist, Stephen Boulton, Max Thomson, Ricardo Marius, Mohsen Hooshyar, Scott McComb, Rozanne Arulanandam, Carolina Solange Ilkow, John Cameron Bell, Jean-Simon Diallo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Targeted antineoplastic immunotherapies have achieved remarkable clinical outcomes. However, resistance to these therapies due to target absence or antigen shedding limits their efficacy and excludes tumours from candidacy. To address this l
Externí odkaz:
https://doaj.org/article/f45d398fc89f455a93faf9739ef489c7
Autor:
Marie-Eve Wedge, Victoria A. Jennings, Mathieu J. F. Crupi, Joanna Poutou, Taylor Jamieson, Adrian Pelin, Giuseppe Pugliese, Christiano Tanese de Souza, Julia Petryk, Brian J. Laight, Meaghan Boileau, Zaid Taha, Nouf Alluqmani, Hayley E. McKay, Larissa Pikor, Sarwat Tahsin Khan, Taha Azad, Reza Rezaei, Bradley Austin, Xiaohong He, David Mansfield, Elaine Rose, Emily E. F. Brown, Natalie Crawford, Almohanad Alkayyal, Abera Surendran, Ragunath Singaravelu, Dominic G. Roy, Gemma Migneco, Benjamin McSweeney, Mary Lynn Cottee, Egon J. Jacobus, Brian A. Keller, Takafumi N. Yamaguchi, Paul C. Boutros, Michele Geoffrion, Katey J. Rayner, Avijit Chatterjee, Rebecca C. Auer, Jean-Simon Diallo, Derrick Gibbings, Benjamin R. tenOever, Alan Melcher, John C. Bell, Carolina S. Ilkow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
RNA-based viruses can be engineered to express artificial microRNAs (amiRNAs). Here, the authors identify a candidate amiRNA that confers a replicative advantage to oncolytic viruses, enhancing their anticancer potency, and show that intercellular tr
Externí odkaz:
https://doaj.org/article/4c63ee51ae0d403a99532dab542cb349
Autor:
Abera Surendran, Monire Jamalkhah, Joanna Poutou, Rayanna Birtch, Christine Lawson, Jaahnavi Dave, Mathieu J. F. Crupi, Justin Mayer, Victoria Taylor, Julia Petryk, Christiano Tanese de Souza, Neil Moodie, Jacob Lecompte Billingsley, Bradley Austin, Nicole Cormack, Natalie Blamey, Reza Rezaei, Curtis W. McCloskey, Emily E. F. Fekete, Harsimrat K. Birdi, Serge Neault, Taylor R. Jamieson, Brenna Wylie, Sarah Tucker, Taha Azad, Barbara Vanderhyden, Lee-Hwa Tai, John C. Bell, Carolina S. Ilkow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAdipocytes in the tumour microenvironment are highly dynamic cells that have an established role in tumour progression, but their impact on anti-cancer therapy resistance is becoming increasingly difficult to overlook.MethodsWe investigat
Externí odkaz:
https://doaj.org/article/6f4b17f759de414f8da10ac2aa3a216f
Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy
Autor:
Fanny Tzelepis, Harsimrat Kaur Birdi, Anna Jirovec, Silvia Boscardin, Christiano Tanese de Souza, Mohsen Hooshyar, Andrew Chen, Keara Sutherland, Robin J. Parks, Joel Werier, Jean-Simon Diallo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 240-252 (2020)
Prime-boost vaccination employing heterologous viral vectors encoding an antigen is an effective strategy to maximize the antigen-specific immune response. Replication-deficient adenovirus serotype 5 (Ad5) is currently being evaluated clinically in N
Externí odkaz:
https://doaj.org/article/85c0f1ffc30c4c7e93249fbf227e89f3
Autor:
Marisa Market, Gayashan Tennakoon, Juliana Ng, Marlena Scaffidi, Christiano Tanese de Souza, Michael A. Kennedy, Rebecca C. Auer
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The majority of data on human Natural Killer (NK) cell phenotype and function has been generated using cryopreserved peripheral blood mononuclear cells (PBMCs). However, cryopreservation can have adverse effects on PBMCs. In contrast, investigating i
Externí odkaz:
https://doaj.org/article/1ed42224266b4e448315de92cadf8b7f
Autor:
Lee-Hwa Tai, Abhirami A. Ananth, Rashmi Seth, Almohanad Alkayyal, Jiqing Zhang, Christiano Tanese de Souza, Phillip Staibano, Michael A. Kennedy, Rebecca C. Auer
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Cancer surgery can promote tumour metastases and worsen prognosis, however, the effect of perioperative complications on metastatic disease remains unclear. In this study we sought to evaluate the effect of common perioperative co
Externí odkaz:
https://doaj.org/article/26e6ba41e05f4b9fa2208dcd5ae948d1
Autor:
Leonard Angka, Christiano Tanese de Souza, Katherine E. Baxter, Sarwat T. Khan, Marisa Market, Andre B. Martel, Lee-Hwa Tai, Michael A. Kennedy, John C. Bell, Rebecca C. Auer
Publikováno v:
Molecular Therapy. 30:3270-3283
Profound natural killer (NK) cell suppression after cancer surgery is a main driver of metastases and recurrence, for which there is no clinically approved intervention available. Surgical stress is known to cause systemic postoperative changes that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd384ad9edb2882b157562299d2065f6
https://doi.org/10.1016/j.ymthe.2022.05.024
https://doi.org/10.1016/j.ymthe.2022.05.024
Autor:
Rebecca C. Auer, John C. Bell, David F. Stojdl, E. Celia Marginean, Blair Macdonald, Greg O. Cron, Andrew P. Makrigiannis, Ahmad Bakur Mahmoud, Abhirami A. Ananth, Shalini Sahi, Charles Lefebvre, Jiqing Zhang, Christiano Tanese de Souza, Michael A. Kennedy, Lee-Hwa Tai, Almohanad A. Alkayyal
Intra-tumoral vaccination is essential to maximize the benefit of MG1-IL12-ICV vaccine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ec9cfc7b70d597de21435ea20cb05a
https://doi.org/10.1158/2326-6066.22538810.v1
https://doi.org/10.1158/2326-6066.22538810.v1
Autor:
Rebecca C. Auer, John C. Bell, David F. Stojdl, E. Celia Marginean, Blair Macdonald, Greg O. Cron, Andrew P. Makrigiannis, Ahmad Bakur Mahmoud, Abhirami A. Ananth, Shalini Sahi, Charles Lefebvre, Jiqing Zhang, Christiano Tanese de Souza, Michael A. Kennedy, Lee-Hwa Tai, Almohanad A. Alkayyal
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c71604e02be090292e90c4d3e38073
https://doi.org/10.1158/2326-6066.22538798
https://doi.org/10.1158/2326-6066.22538798
Autor:
Rebecca C. Auer, John C. Bell, David F. Stojdl, E. Celia Marginean, Blair Macdonald, Greg O. Cron, Andrew P. Makrigiannis, Ahmad Bakur Mahmoud, Abhirami A. Ananth, Shalini Sahi, Charles Lefebvre, Jiqing Zhang, Christiano Tanese de Souza, Michael A. Kennedy, Lee-Hwa Tai, Almohanad A. Alkayyal
Despite improvements in chemotherapy and radical surgical debulking, peritoneal carcinomatosis (PC) remains among the most common causes of death from abdominal cancers. Immunotherapies have been effective for selected solid malignancies, but their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66212810c1ebef502b2444aa8579d15b
https://doi.org/10.1158/2326-6066.c.6548900
https://doi.org/10.1158/2326-6066.c.6548900