Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Christiane Sahm"'
Autor:
Christian Brendel, Torsten Tonn, Christiane Sahm, Halvard Bonig, Marcus Odendahl, Kurt Schönfeld, Stephan Kloess, Congcong Zhang, Sylvia Köhler, Klaus Kühlcke, Anna Jauch, Manfred Schmidt, Heidi Holtgreve-Grez, Ralf Schubert, Michael A. Rieger, Sonja Naundorf, Erhard Seifried, Ulrike Köhl, Hans G. Klingemann, Manuel Grez, Paulina Nowakowska, Winfried S. Wels
Publikováno v:
Molecular Therapy. 23(2):330-338
Natural killer (NK) cells are an important effector cell type for adoptive cancer immunotherapy. Similar to T cells, NK cells can be modified to express chimeric antigen receptors (CARs) to enhance antitumor activity, but experience with CAR-engineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557f08162d82c317c898c6da25103509
Publikováno v:
Cancer Immunology, Immunotherapy. 61:1451-1461
Natural killer (NK) cells hold promise for adoptive cancer immunotherapy but are dependent on cytokines such as interleukin (IL)-2 for growth and cytotoxicity. Here, we investigated the consequences of ectopic expression of IL-15 in human NK cells. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5eaf4a0946136c508fcff33256360f
https://doi.org/10.1007/s00262-012-1212-x
https://doi.org/10.1007/s00262-012-1212-x
Autor:
Christian Brendel, Lukas Jennewein, Sabrina Genßler, Erhard Seifried, Halvard Bonig, Torsten Tonn, Ulrike Köhl, Christiane Sahm, Kurt Schönfeld, Michel Mittelbronn, Marcus Odendahl, Manuel Grez, Winfried S. Wels, Joachim P. Steinbach, Michael C. Burger, S. Naundorf, Congcong Zhang, Paulina Nowakowska
Publikováno v:
Neuro-Oncology. 16:iii44-iii44
BACKGROUND: While EGFRvIII appears a logical target for immunotherapy, only a subpopulation of tumor cells express EGFRvIII and immune escape has been demonstrated. ErbB2 is overexpressed in a substantial proportion of glioblastomas and has been succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b825a8ad7dfe4330a4eda7ec999a18f6
https://doi.org/10.1093/neuonc/nou209.9
https://doi.org/10.1093/neuonc/nou209.9
Autor:
Joachim P. Steinbach, Sabrina Genβler, Kurt Schönfeld, Christiane Sahm, Manuel Grez, Sonja Naundorf, Michael C. Burger, Winfried S. Wels, Torsten Tonn, Marcus Odendahl, Paulina Nowakowska, Congcong Zhang
Publikováno v:
Journal for Immunotherapy of Cancer
Poster presentation: 28th Annual Scientific Meeting of the Society for Immunotherapy of Cancer (SITC) Significant progress has been made over the last decade towards realizing the potential of natural killer (NK) cells for cancer immunotherapy. NK ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2ada6ab9827e4fe5384ff92df69852
http://europepmc.org/articles/PMC3990952
http://europepmc.org/articles/PMC3990952
Autor:
Michael C. Burger, Winfried S. Wels, Marcus Odendahl, Christian Brendel, Ulrike Köhl, Manuel Grez, Sabrina Genßler, Kurt Schönfeld, Sonja Naundorf, Concong Zhang, Torsten Tonn, Joachim P. Steinbach, Christiane Sahm
Publikováno v:
Cancer Research. 73:3967-3967
In addition to primary natural killer (NK) cells, continuously growing cytotoxic cell lines such as NK-92 are being considered for adoptive cancer immunotherapy. High cytotoxicity of NK-92 has been shown against malignant cells of hematologic origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1590a633c9fb011a34fb6d0564c536
https://doi.org/10.1158/1538-7445.am2013-3967
https://doi.org/10.1158/1538-7445.am2013-3967