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pro vyhledávání: '"Christiane Nieth"'
Publikováno v:
Cancer gene therapy. 11(11)
Multidrug resistance (MDR) is the major cause of failure of effective chemotherapeutic treatment of disseminated neoplasms. The "classical" MDR phenotype of human malignancies is mediated by drug extrusion by the adenosine triphosphate binding casset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359c5a15a68d78e60590268c244c9940
https://pubmed.ncbi.nlm.nih.gov/15375376
https://pubmed.ncbi.nlm.nih.gov/15375376
Publikováno v:
FEBS Letters. (2-3):144-150
For reversal of MDR1 gene-dependent multidrug resistance (MDR), two small interfering RNA (siRNA) constructs were designed to inhibit MDR1 expression by RNA interference. SiRNA duplexes were used to treat human pancreatic carcinoma (EPP85-181RDB) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f451c2be69a3f2bb5355e5fcd515d90f