Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Christiane Neuber"'
Autor:
Nele Warnecke, Bärbel M. Ulmer, Sandra D. Laufer, Aya Shibamiya, Elisabeth Krämer, Christiane Neuber, Sophia Hanke, Charlotta Behrens, Malte Loos, Julia Münch, Jirko Kühnisch, Sabine Klaassen, Thomas Eschenhagen, Monica Patten-Hamel, Lucie Carrier, Giulia Mearini
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102489- (2021)
MYBPC3 is the most frequently affected gene in hypertrophic cardiomyopathy (HCM), which is an autosomal-dominant cardiac disease caused by mutations in sarcomeric proteins. Bi-allelic truncating MYBPC3 mutations are associated with severe forms of ne
Externí odkaz:
https://doaj.org/article/823c7120cb5b4e818f122df69c905bed
Autor:
András Horváth, Marc D. Lemoine, Alexandra Löser, Ingra Mannhardt, Frederik Flenner, Ahmet Umur Uzun, Christiane Neuber, Kaja Breckwoldt, Arne Hansen, Evaldas Girdauskas, Hermann Reichenspurner, Stephan Willems, Norbert Jost, Erich Wettwer, Thomas Eschenhagen, Torsten Christ
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 822-833 (2018)
Summary: Human induced pluripotent stem cell (hiPSC) cardiomyocytes (CMs) show less negative resting membrane potential (RMP), which is attributed to small inward rectifier currents (IK1). Here, IK1 was measured in hiPSC-CMs (proprietary and commerci
Externí odkaz:
https://doaj.org/article/765df07f0c0c43ed82a5ff471e27ab74
Autor:
Marc D. Lemoine, Ingra Mannhardt, Kaja Breckwoldt, Maksymilian Prondzynski, Frederik Flenner, Bärbel Ulmer, Marc N. Hirt, Christiane Neuber, András Horváth, Benjamin Kloth, Hermann Reichenspurner, Stephan Willems, Arne Hansen, Thomas Eschenhagen, Torsten Christ
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising tool for drug testing and modelling genetic disorders. Abnormally low upstroke velocity is a current limitation. Here we investigated the use of 3D enginee
Externí odkaz:
https://doaj.org/article/2e69ee578b0a4779a389e8f3a0ff7687
Autor:
Ingra Mannhardt, Kaja Breckwoldt, David Letuffe-Brenière, Sebastian Schaaf, Herbert Schulz, Christiane Neuber, Anika Benzin, Tessa Werner, Alexandra Eder, Thomas Schulze, Birgit Klampe, Torsten Christ, Marc N. Hirt, Norbert Huebner, Alessandra Moretti, Thomas Eschenhagen, Arne Hansen
Publikováno v:
Stem Cell Reports, Vol 7, Iss 1, Pp 29-42 (2016)
Analyzing contractile force, the most important and best understood function of cardiomyocytes in vivo is not established in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM). This study describes the generation of 3D, strip-forma
Externí odkaz:
https://doaj.org/article/b1daac147592484a98d637f6bdda35b3
Autor:
Christiane Neuber, June Uebeler, Thomas Schulze, Hannieh Sotoud, Ali El-Armouche, Thomas Eschenhagen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98893 (2014)
Endoplasmic reticulum (ER) stress has been implicated in a variety of cardiovascular diseases. During ER stress, disruption of the complex of protein phosphatase 1 regulatory subunit 15A and catalytic subunit of protein phosphatase 1 by the small mol
Externí odkaz:
https://doaj.org/article/41cfb38730634a7796e1199428f0a385
Autor:
Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emmons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke
Publikováno v:
PLoS ONE, Vol 6, Iss 7 (2011)
Externí odkaz:
https://doaj.org/article/f4e6a310bb8b4df3959461e9c6f0a893
Autor:
Ali El-Armouche, Alexander Peter Schwoerer, Christiane Neuber, Julius Emons, Daniel Biermann, Thomas Christalla, Adam Grundhoff, Thomas Eschenhagen, Wolfram Hubertus Zimmermann, Heimo Ehmke
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14263 (2010)
BackgroundMechanical overload leads to cardiac hypertrophy and mechanical unloading to cardiac atrophy. Both conditions produce similar transcriptional changes including a re-expression of fetal genes, despite obvious differences in phenotype. MicroR
Externí odkaz:
https://doaj.org/article/f7b34f21c2c045f49d98f65bbcbf7772
Autor:
Magdolna K. Levay, Kurt A. Krobert, Andreas Vogt, Atif Ahmad, Andreas Jungmann, Christiane Neuber, Sebastian Pasch, Arne Hansen, Oliver J. Müller, Susanne Lutz, Thomas Wieland
The role and outcome of the muscarinic M2 acetylcholine receptor (M2R) signaling in healthy and diseased cardiomyocytes is still a matter of debate. Here, we report that the long isoform of the regulator of G protein signaling 3 (RGS3L) functions as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd7317c7374ea109ff297cb6c4c6315
http://hdl.handle.net/10852/101030
http://hdl.handle.net/10852/101030
Autor:
Magdolna K, Levay, Kurt A, Krobert, Andreas, Vogt, Atif, Ahmad, Andreas, Jungmann, Christiane, Neuber, Sebastian, Pasch, Arne, Hansen, Oliver J, Müller, Susanne, Lutz, Thomas, Wieland
Publikováno v:
Basic research in cardiology. 117(1)
The role and outcome of the muscarinic M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdb935e8fde11d3b1b79652901dfc680
https://pubmed.ncbi.nlm.nih.gov/35230541
https://pubmed.ncbi.nlm.nih.gov/35230541
Autor:
Marina Reinsch, Thomas G. Schulze, Anika E Knaust, Aya Shibamiya, Florian Weinberger, Sandra D. Laufer, Birgit Klampe, Christiane Neuber, Simone Steuck, Giulia Mearini, Elisabeth Schulze, Malte Loos, Ingra Mannhardt, Mirja L Schulze, Charlotta Sophie Behrens, Bärbel M. Ulmer, Arne Hansen, Dana Krauß, Tessa Werner, Marta Lemme, Umber Saleem, Christa Augustin, Sigrid Fuchs, Thomas Eschenhagen
Publikováno v:
Current Protocols in Stem Cell Biology. 55
The reproducibility of stem cell research relies on the constant availability of quality-controlled cells. As the quality of human induced pluripotent stem cells (hiPSCs) can deteriorate in the course of a few passages, cell banking is key to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb5236c1a3d53cab08e444c75ce55de4
https://doi.org/10.1002/cpsc.127
https://doi.org/10.1002/cpsc.127