Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christiane Mittmann"'
Autor:
Umberto Maccio, Alanna Mihic, Daniela Lenggenhager, Isabel Kolm, Christiane Mittmann, Mathias Heikenwälder, Anna Lorentzen, Daniela Mihic-Probst
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10745 (2022)
Hypoxia affects tumor aggressiveness and activates pathways associated with epithelial mesenchymal transition (EMT) which are crucial for tumor progress. In this study, the correlation of hypoxia and EMT with sentinel lymph node status and tumor-spec
Externí odkaz:
https://doaj.org/article/57fd3420225e44ea95859e7513a960c4
Autor:
Peter Schraml, Holger Moch, Tullio Sulser, Maries van den Broek, Cédric Poyet, Thomas Hermanns, Arndt Hartmann, Anna M. Nowicka, Christiane Mittmann, Melanie Ruf
A) Western blot of HIF1α, HIF2α and CD70 in SLR22 after silencing of HIF1α, HIF2α or both together for 48 h and 72 h. B) Western blot of HIF2α and CD70 in SLR24 and C) SLR22 after transient overexpression of HIF2α and D) in A498 and E) SLR22 af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12e2b84f0c42b77f986668c107624cd7
https://doi.org/10.1158/1078-0432.22460595.v1
https://doi.org/10.1158/1078-0432.22460595.v1
Autor:
Peter Schraml, Holger Moch, Tullio Sulser, Maries van den Broek, Cédric Poyet, Thomas Hermanns, Arndt Hartmann, Anna M. Nowicka, Christiane Mittmann, Melanie Ruf
Supplementary table S1: Antibodies used for Western blot analysis, immunohistochemistry and ChIP. Supplementary table S2: VHL and HIF1α mutation states in cell lines. Supplementary table S3: Primers used for ChIP analysis. Supplementary table S4: Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ea2a52b28c33c40d0f699502f52d09
https://doi.org/10.1158/1078-0432.22460583
https://doi.org/10.1158/1078-0432.22460583
Autor:
Jan Hendrik Rüschoff, Martina Haberecker, Zoi Tsourti, Kristiaan Nackaerts, Marc de Perrot, Luka Brcic, Ernest Nadal, Sotirios Tsimpoukis, Steven G. Gray, Luca Ampollini, Joachim G. Aerts, Emanuela Felley-Bosco, Michaela B. Kirschner, Kim Monkhorst, Birgit Weynand, Fatemeh Bavaghar-Zaeimi, Miroslav Samarzija, Roger Llatjos, Stephen P. Finn, Enrico Silini, Jan von der Thüsen, Nesa Marti, Karerina Vervita, Roswitha Kammler, Solange Peters, Rolf A. Stahel, Paul Baas, Isabelle Opitz, Rolf Stahel, Anita Hiltbrunner, Rosita Kammler, Patrick Vagenknecht, Barbara Ruepp, Urania Dafni, Panagiota Zygoura, Katerina Vervita, Georgia Dimopoulou, Charitini Andriakopoulou, Androniki Stavrou, Jan H. Rüschoff, Susanne Dettwiler, Fabiola Prutek, Christiane Mittmann, Bart Vrugt, Martina Friess, Alessandra Matter, Chloé Spichiger-Häusermann, Eric Verbeken, Birgit Weyenand, Liesbet Peeters, Marcello Tiseo, Enrico Maria Silini, Luigi Ventura, Letizia Gnetti, Paolo Carbognani, Fatemeh B. Zaeimi, Sven Seiwerth, Marko Jakopovic, Felipe Cardenal, Susana Lorente, Konstantinos Syrigos, Ioannis Vamvakaris, Paraskevi Boura, Steven Gray, Mutaz Mohammed Nur, Anne-Marie Baird, Martin Barr, Sinead Cuffe, Kathy Gately, Joachim Aerts
Publikováno v:
Modern Pathology, 35(12), 1888-1899. SPRINGERNATURE
Modern Pathology, 35(12), 1888-1899. Nature Publishing Group
Modern Pathology, 35(12), 1888-1899. Nature Publishing Group
Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Although histology and pathologic stage are important prognostic factors, better prognostic biomarkers are needed. The ribosomal protein S6 is a downstream target of the phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355b5c339b724ea833e0f7b1c96df40e
https://doi.org/10.1038/s41379-022-01145-0
https://doi.org/10.1038/s41379-022-01145-0
Autor:
Raymond L. Barnhill, Ann-Katrin Rodewald, Daniel Kirschenbaum, Christiane Mittmann, Claire Lugassy, Daniela Mihic-Probst, Holger Moch, Joanna Mangana, Elisabeth J. Rushing
Publikováno v:
Journal of Cutaneous Pathology. 46:570-578
BACKGROUND Metastatic tumor spread is a complex multistep process. Due to the blood-brain barrier, metastasis to the central nervous system is restrictive with a distinct predilection for certain tumor types. In melanoma patients, brain metastasis is
Autor:
Arnulf Stenzl, Christoph A. Karlo, Holger Moch, Qing Zhong, Manuela Schmidinger, Iris Blume, Jens Bedke, Ursula M. Vogl, Peter Schraml, Axel Mischo, Svenja Bihr, Christiane Mittmann, Jörg Hennenlotter, Michael Prummer, Magdalena Lukamowicz-Rajska
Publikováno v:
Oncotarget
Oncotarget, 7 (48)
Oncotarget, 7 (48)
A number of treatments targeting VEGF or mTOR pathways have been approved for metastatic clear cell Renal Cell Carcinoma (ccRCC), but the majority of patients show disease progression after first line therapy with a very low rate of complete or long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a85588db2f75b2f635ce604010f87dd
Autor:
Holger Moch, Dorothee Pflueger, Silvia Dehler, Mark A. Rubin, Peter Schraml, Christiane Mittmann
Publikováno v:
BMC Genomics, 16
BMC Genomics
BMC Genomics
Background Chimeric read-through RNAs are transcripts originating from two directly adjacent genes (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fd8fe19cdbb65da9ff9ef4b235ed78
https://hdl.handle.net/20.500.11850/101422
https://hdl.handle.net/20.500.11850/101422
Autor:
Cédric Poyet, Anna M. Nowicka, Melanie Ruf, Arndt Hartmann, Christiane Mittmann, Maries van den Broek, Peter Schraml, Thomas Hermanns, Holger Moch, Tullio Sulser
Publikováno v:
Clinical Cancer Research
Purpose: CD70, a member of the TNF ligand superfamily, has been shown frequently overexpressed in clear cell renal cell carcinoma (ccRCC). The mechanisms of CD70′s upregulation and its role in ccRCC are unknown. Experimental Design: CD70 expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970fe673e6e0c81fc31e06d264525f35
https://doi.org/10.5167/uzh-111400
https://doi.org/10.5167/uzh-111400