Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Christiane Mercier"'
Autor:
Mercier, Christine, Grail, Denise, Galant, Christian
Publikováno v:
Archorales : les métiers de la recherche, témoignages. (15), 2012, 3-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1582::ab9b32ace2699d19e28410b0f5badfea
http://prodinra.inra.fr/record/348025
http://prodinra.inra.fr/record/348025
Autor:
Jose M. Pla Delfina, Marival Bermejo, Gérard Trouiller, Patrick Vizet, Virginia Merino, Antonio Mulet, Christiane Mercier, Teresa María Garrigues
Publikováno v:
Journal of Pharmaceutical Sciences. 88:398-405
Absorption rate constants (in situ rat gut technique) and in vitro antibacterial activities of twenty fluoroquinolones have been evaluated. A biophysical model that relates the absorption of the compounds with their lipophilicity was fitted. The mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b658609b1f3cad840fc10f584f8957
https://doi.org/10.1021/js980370+
https://doi.org/10.1021/js980370+
Autor:
C. Boissart, François Sichel, J. C. Lancelot, Pascal Gauduchon, Stéphane Chemtob, A. Tallec, E. Raoult, M. Robba, Christiane Mercier, Véronique André, J. Y. Le Talaer
Publikováno v:
Mutation Research/Genetic Toxicology. 345:11-25
The mutagenicity of 4 ortho-aminonitrocarbazoles and 2 ortho-acetamidonitrocarbazoles was assayed in Salmonella strains TA1538, TA98, TA100, TA1537 and TA1977 and in nitroreductase and acetylase deficient strains TA98NR and TA98/1,8DNP 6 , with and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9005dfe3536b4f73e56eed75b8de98
https://doi.org/10.1016/0165-1218(95)90066-7
https://doi.org/10.1016/0165-1218(95)90066-7
Autor:
Anna Shapiro, Christiane Mercier
Publikováno v:
Science of The Total Environment. 143:75-92
Food safety is a growing preoccupation of the health authorities and the major food companies in any European country. All the aspects of food manufacturing, from the raw materials until the product is consumed have to insure they are innoxious to hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a6b5c27680da1da5534921a117f1f3
https://doi.org/10.1016/0048-9697(94)90534-7
https://doi.org/10.1016/0048-9697(94)90534-7
Publikováno v:
European Journal of Medicinal Chemistry. 28:811-819
The DARC/PELCO and OASIS methods have been applied to model the PNMT inhibitory potency of 22 benzylamines and 31 amphetamines. In both series, the activity was explained by the same groups of parameters: the hydrophobicity and superdelocalizability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c596499b02fc5574cc9ea34987d040
https://doi.org/10.1016/0223-5234(93)90116-v
https://doi.org/10.1016/0223-5234(93)90116-v
Publikováno v:
Journal of Mathematical Chemistry. 9:351-357
The regular evolution of properties with structural modification is quantitatively formulated. It is defined in a structural space which is exhaustive, ordered, flexible and explicit. It is detected along the ordered pathways of structural filiations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0dfd9996854679f670440140bca7fdb
https://doi.org/10.1007/bf01166098
https://doi.org/10.1007/bf01166098
Publikováno v:
European Journal of Medicinal Chemistry. 26:575-592
Two QSAR approaches have been compared in detail. The DARC/PELCO method is based on the exhaustive generation of all topochromatic sites around the reference structure and the evaluation of their contribution to the property. The OASIS system is an o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52839474fec71b0bd758d9bcf7cc4022
https://doi.org/10.1016/0223-5234(91)90192-p
https://doi.org/10.1016/0223-5234(91)90192-p
Publikováno v:
Journal of Medicinal Chemistry. 34:934-942
We present our general system for QSAR search, CALPHI (Computer-Aided Law by Hyperstructure Investigation) set up in the context of the DARC structural language. We use it to construct global, fragmentary, and topological models of the capacity of al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94fd8292433bd87d2b2194a4e04ebfc
https://doi.org/10.1021/jm00107a010
https://doi.org/10.1021/jm00107a010
Publikováno v:
Quantitative Structure-Activity Relationships. 9:88-93
A dynamic method for the setting up and computer-aided handling of an “ANTICHOLINERGIC” data bank has been designed in order to rationalize the planning of pharmacological and chemical experimentation with a view to optimizing series known to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12306e77b914051e8e4cd57f34f1b756
https://doi.org/10.1002/qsar.19900090203
https://doi.org/10.1002/qsar.19900090203
Publikováno v:
Computer-Assisted Lead Finding and Optimization: Current Tools for Medicinal Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6aa9c20d1db7811dcf83b85d0791181
https://doi.org/10.1002/9783906390406.ch22
https://doi.org/10.1002/9783906390406.ch22