1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses

Autor: Luana da S. M. Forezi, Thiago Moreno L. Souza, Leonardo Brozeguini, Anna C. Cunha, Fernanda da C. S. Boechat, Fernanda S. Sagrillo, Carolina Q. Sacramento, Christiane M. Nogueira, Maria Cecília B. V. de Souza, Isakelly P. Marques, Vitor F. Ferreira, Cecília S. Riscado, Osvaldo A. Santos-Filho, Letícia V. Faro, Natalia Fintelman-Rodrigues

Publikováno v: Bioorganic & Medicinal Chemistry. 23:7777-7784

We described the synthesis of a new congener series of 1,2,3-triazolyl-4-oxoquinolines and evaluated their ability to inhibit oseltamivir (OST)-resistant influenza strains. Oxoquinoline derivative 1i was the most potent compound within this series, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c117a7e4f7c186f1cf79887fb0ef9e
https://doi.org/10.1016/j.bmc.2015.11.028

Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives

Autor: Christiane M. Nogueira, Maria Cecília B. V. de Souza, Vitor F. Ferreira, Jairo R. Temerozo, Izabel C. P. Paixão, Claudio Cesar Cirne-Santos, Anna C. Cunha, Viveca Giongo, Carlos Rangel Rodrigues, Bruno R. Simonetti, Dumith Chequer Bou-Habib, Juliana Eymara Barbosa, Pedro N. Batalha, David de O. Silva, Thiago Moreno L. Souza, Paula Alvarez Abreu, Helena Carla Castro, Valéria Garrido, Fernanda da C. Santos

Publikováno v: Bioorganic & Medicinal Chemistry. 17:5476-5481

In the present article, we describe the synthesis, anti-HIV1 profile and molecular modeling evaluation of 11 oxoquinoline derivatives. The structure-activity relationship analysis revealed some stereoelectronic properties such as LUMO energy, dipole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb80a5a6053668b2309e613d748a86ab
https://doi.org/10.1016/j.bmc.2009.06.037

Lessons from the Terra Preta de Índios of the Amazon region for the utilisation of charcoal for soil amendment

Autor: Etelvino Henrique Novotny, Christiane M. Nogueira, Tito José Bonagamba, Michael H. B. Hayes, Andre Souza, Eduardo Ribeiro de Azevêdo, Beata Emoke Madari, Antonio S. Mangrich, Guixue Song

Publikováno v: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice)
Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
Journal of the Brazilian Chemical Society, Volume: 20, Issue: 6, Pages: 1003-1010, Published: 2009
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of the Brazilian Chemical Society v.20 n.6 2009
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Scopus-Elsevier

The potential of charcoal and of partially combusted organic waste to mimic the soil organic matter of the Terras Pretas de Índios (Amazonian Dark Earths) from the Amazon Region is discussed. These materials serve as soil conditioners and as sequest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e2c36af60daa6fc18553541b153a04
http://www.alice.cnptia.embrapa.br/alice/handle/doc/659439

Complete and unambiguous assignments of 1H and 13C chemical shifts of new arylamino derivatives of ortho-naphthofuranquinones

Autor: Eufrânio N, da Silva Júnior, Maria Cecília B V, de Souza, Antônio V, Pinto, Maria do Carmo F R, Pinto, Christiane M, Nogueira, Vitor F, Ferreira, Rodrigo B V, Azeredo

Publikováno v: Magnetic resonance in chemistry : MRC. 46(12)

Six new nor-beta-lapachones have been synthesized from reaction of 3-bromo-nor-beta-lapachone with arylamines. These derivatives have potent anticancer properties against several cell lines. Here, we report complete unambiguous assignments of (1)H an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d98a8be0cf5d3f9a99e3537c5026e25c
https://pubmed.ncbi.nlm.nih.gov/18524015