Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Christiane Hesse"'
Autor:
Lars‐Erik Broksø Kyhl, Christiane Hesse, Per Larsson, Katharina Bruzelius, Bernadette Mannaerts
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1590-1599 (2021)
Abstract The purpose of this first‐in‐human trial was to examine the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of a novel recombinant human chorionic gonadotropin (rhCG; FE 999302, choriogonadotropin beta) to support its clinical d
Externí odkaz:
https://doaj.org/article/b54ddc441b984e52b31454e1b9bfcfaf
Autor:
Katharina Bruzelius, Lars-Erik Broksø Kyhl, Bernadette Mannaerts, Per Larsson, Christiane Hesse
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1590-1599 (2021)
Clinical and Translational Science
Clinical and Translational Science
The purpose of this first‐in‐human trial was to examine the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of a novel recombinant human chorionic gonadotropin (rhCG; FE 999302, choriogonadotropin beta) to support its clinical developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92918dfb34b0932bc5c9593808445f3
https://doaj.org/article/b54ddc441b984e52b31454e1b9bfcfaf
https://doaj.org/article/b54ddc441b984e52b31454e1b9bfcfaf
Publikováno v:
Pulmonary circulation. 6(Suppl 1)
Riociguat (BAY 63-2521) is the first member of a novel class of compounds, the soluble guanylate cyclase (sGC) stimulators. Riociguat has a dual mode of action: it sensitizes sGC to endogenous nitric oxide (NO) and stimulates sGC independent of NO av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c685888009780e058de264fa0cae877
https://pubmed.ncbi.nlm.nih.gov/27096084
https://pubmed.ncbi.nlm.nih.gov/27096084
Autor:
Christiane Hesse-Lang
Publikováno v:
Zeitschrift für Konfliktmanagement. 20:109-110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1226eb4bc07111ed322afdba8deee94
https://doi.org/10.9785/zkm-2017-0309
https://doi.org/10.9785/zkm-2017-0309
Autor:
Darrell R. Schroeder, Michael J. Joyner, Stephen T. Turner, Alan R. Penheiter, John H. Eisenach, Christiane Hesse, Emma C. Hart, Wayne T. Nicholson, Timothy B. Curry
Publikováno v:
The Journal of Physiology. 588:2669-2678
Regional infusions of β2-adrenoceptor (ADRB2) agonist have generally shown that individuals homozygous for Gly16 produces greater vasodilatation than those homozygous for Arg16. Systemic infusions have shown an opposite effect on systemic vascular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d917329b37a5139dd43814a6ab9e115a
https://doi.org/10.1113/jphysiol.2010.190058
https://doi.org/10.1113/jphysiol.2010.190058
Publikováno v:
Hypertension. 50:41-46
Patients with hypertension have a blunted sensitivity of baroreflex control of heart period. In these patients, baroreflex sensitivity is positively related to heart rate variability and inversely related to blood pressure variability. We hypothesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd417642b47c0669f734b710c0e1608
https://doi.org/10.1161/hypertensionaha.107.090308
https://doi.org/10.1161/hypertensionaha.107.090308
Autor:
Kristina Unnebrink, Marianne de Bruijn, Heike Siedler, Gerd Mikus, Michiel H. De Vries, Monika Seibert-Grafe, Christiane Hesse, Edu Zondag, Walter E. Haefeli, Steffen Luntz
Publikováno v:
British Journal of Clinical Pharmacology. 61:414-419
Aims To investigate the pharmacokinetics and the pharmacodynamic effects in dorsal hand veins of the neurokinin-1 receptor antagonist SLV317. Methods In a randomized, double-blind, placebo-controlled cross-over study 19 healthy men received a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df14065b815314d5b65754f457a02ddd
https://doi.org/10.1111/j.1365-2125.2006.02590.x
https://doi.org/10.1111/j.1365-2125.2006.02590.x
Publikováno v:
Journal of Clinical Psychopharmacology. 25:589-592
Sildenafil used as oral drug treatment for erectile dysfunction is predominantly metabolized by the cytochrome P450 isozyme 3A4. The antidepressant fluvoxamine is an inhibitor of cytochrome P450 3A4. In a randomized, double-blind, placebo-controlled,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc598d507a4ace96a524725ca278756
https://doi.org/10.1097/01.jcp.0000186866.82665.29
https://doi.org/10.1097/01.jcp.0000186866.82665.29
Autor:
Heike Siedler, Malte Kelm, Christoph Dehnert, Walter E. Haefeli, Hubert J. Bardenheuer, Marc M. Berger, Peter Bärtsch, Petra Kleinbongard, Christiane Hesse
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:763-767
High-altitude pulmonary edema (HAPE) is characterized by excessive pulmonary vasoconstriction and is associated with decreased concentrations of nitric oxide (NO) in the lung.We hypothesized that individuals susceptible to HAPE (HAPE-S) would also ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df52f0d8891c3c0ccc0ced2fcecf216
https://doi.org/10.1164/rccm.200504-654oc
https://doi.org/10.1164/rccm.200504-654oc
Autor:
Yorki Tayrouz, Ulrich Mansmann, Michael M. Hoffmann, Kristina Unnebrink, Walter E. Haefeli, Johanna Weiss, Christiane Hesse, Ruth Fricker
Publikováno v:
British Journal of Clinical Pharmacology. 58:169-177
Aims Polymorphisms of the NOSIII gene and of the CYBA gene have been associated with a number of pathological conditions such as arterial hypertension, coronary artery disease, and myocardial infarction. Because endothelium-dependent vasodilation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26925f2d1a126368665a7b680cb50533
https://doi.org/10.1111/j.1365-2125.2004.02130.x
https://doi.org/10.1111/j.1365-2125.2004.02130.x