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pro vyhledávání: '"Christiane E. Olivero"'
Autor:
Christiane E. Olivero, Nadya Dimitrova
Publikováno v:
The FASEB Journal
Long noncoding RNAs (lncRNAs) have emerged as key regulators in a variety of cellular processes that influence disease states. In particular, many lncRNAs are genetically or epigenetically deregulated in cancer. However, whether lncRNA alterations ar
Autor:
Jordan Bendor, Jesse R. Zamudio, Nadya Dimitrova, Elena Martínez-Terroba, Christiane E. Olivero, David M. Feldser, Lauren Winkler, Kevin Chen, Ephrath Tesfaye
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance The work by Tesfaye and colleagues defines universal and tumor type–specific features of the p53 tumor suppressor transcriptional network. This study determines a “core” signature of the p53 response across different oncogenic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273e76fc7f85dbf5fc5c7ee82e1b59f2
https://escholarship.org/uc/item/5h27x8c5
https://escholarship.org/uc/item/5h27x8c5
Autor:
Kyle Rhodehouse, Allegra Padula, Christiane E Olivero, Priscilla M. Van Wynsberghe, Laura Aseltine, Joseph S Spina, Rachel Weinstein, Katherine Cascino
Publikováno v:
G3: Genes|Genomes|Genetics
The Caenorhabditis elegans ( C. elegans ) heterochronic pathway, which regulates developmental timing, is thought to be an ancestral form of the circadian clock in other organisms. An essential member of this clock is the Period protein whose homolog
Autor:
Clara Liao, Nima Hooshdaran, Jeremy A. Schofield, Nadya Dimitrova, Jesse R. Zamudio, Christiane E. Olivero, Matthew D. Simon, Jordan Bendor, Elena Martínez-Terroba, Ephrath Tesfaye, Dorthy Fang, Joshua T. Zimmer
Publikováno v:
Mol Cell
Summary The tumor suppressor p53 transcriptionally activates target genes to suppress cellular proliferation during stress. p53 has also been implicated in the repression of the proto-oncogene Myc, but the mechanism has remained unclear. Here, we ide
Autor:
Nadya Dimitrova, Christiane E. Olivero, Ephrath Tesfaye, Elena Martínez-Terroba, Jordan Bendor, Jesse R. Zamudio, Clara Liao, Nima Hooshdaran
Publikováno v:
SSRN Electronic Journal.
The p53 pathway is a key tumor suppressor mechanism that stalls cell cycle progression in response to stress. It has been proposed that p53 suppresses proliferation in part by downregulating the Myc oncogene but the mechanism has remained unclear. He