Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christiane Drougard"'
Autor:
Bakar Bouadjar, Christiane Drougard, Alain Sarasin, Marie-Françoise Avril, Nathalie Bodak, Leela Daya-Grosjean, Sophie Queille
Publikováno v:
Proceedings of the National Academy of Sciences. 96:5117-5122
Recently, hptc , a human gene homologous to the Drosophila segment polarity gene patched ( ptc ), has been implicated in the nevoid basal-cell carcinoma (BCC) syndrome, and somatic mutations of hptc also have been found in sporadic BCCs, the most fre
Autor:
Christiane Drougard, Sophie Seite, Chantal Medaisko, Alain Sarasin, Sophie Queille, Sylvie Tison, Leela Daya-Grosjean, Anny Fourtanier
Publikováno v:
Molecular Carcinogenesis. 22:167-174
We investigated skin lesions induced in hairless SKH:HR1 mice by chronic exposure to a solar ultraviolet light (UV) simulator for alterations of the p53 gene in conserved domains. Mutations of exons 5-8 of the p53 gene in skin lesions were screened i
Autor:
Carl W. Anderson, Alain Sarasin, Ettore Appella, Pierre May, Jean-Claude Ehrhart, Christiane Drougard, Leela Daya-Grosjean, Arlette Duthu, Nicolas Dumaz
Publikováno v:
Molecular carcinogenesis. 20(4)
Trichothiodistrophy (TTD), xeroderma pigmentosum (XP), and Cockayne's syndrome (CS) are three distinct human diseases with sensitivity to ultraviolet (UV) radiation affected by mutations in genes involved in nucleotide excision repair (NER). Among th
The UV component of sunlight is the major carcinogen involved in the etiology of skin cancers. We have studied the rare, hereditary syndrome xeroderma pigmentosum (XP), which is characterized by a very high incidence of cutaneous tumors on exposed sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7b8d78c19aa8f61bb047cdbdfd937a
https://europepmc.org/articles/PMC47810/
https://europepmc.org/articles/PMC47810/
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379:S40
Publikováno v:
Journal of Investigative Dermatology. (5):1162-1170
To understand the relationship between DNA repair, apoptosis, transcription, and cancer-proneness, we have studied the apoptotic response and the recovery of RNA synthesis following ultraviolet C and ultraviolet B irradiation in nucleotide excision r