Effectiveness, safety, and immunogenicity of half dose ChAdOx1 nCoV-19 COVID-19 Vaccine: Viana project

Autor: Valéria Valim, Olindo Assis Martins-Filho, Maria da Penha Gomes Gouvea, Luiz Antônio Bastos Camacho, Daniel Antunes Maciel Villela, Sheila Maria Barbosa de Lima, Adriana Souza Azevedo, Lauro Ferreira Pinto Neto, Carla Magda Allan Santos Domingues, Nésio Fernandes de Medeiros Junior, Isac Ribeiro Moulaz, Laiza Hombre Dias, Samira Tatiyama Miyamoto, Andréa Teixeira-Carvalho, José Geraldo Mill, Half Dose ChAdOx Study Group, Thayná Martins Gouveia, Beatriz Paoli Thompson, Karen Evelin Monlevade Lança, Gabriela Curto Cristianes Lacerda, João Pedro Gonçalves Lenzi, Sabrina de Souza Ramos, Felipe de Castro Pimentel, Ludimila Forechi, Thaís Ruchdeschel, João Pedro Moraes Miossi, Matheus Leite Rassele, Gabriel Smith Sobral Vieira, Laís Pasti, Allan Gonçalves Henriques, Maria Eduarda Morais Hibner Amaral, Alessandro Demoner Ramos, Heitor Filipe Surlo, Laura Gonçalves Rodrigues Aguiar, Luiza Lorenzoni Grillo, Matheus Pereira, Ramon Borge Rizzi, Sara Monteiro Muniz, Hully Cantão dos Santos, Thais Luma de Oliveira Roza, Adriana Santos Silva, Lunara Baptista Ferreira, Karina Lallemand, Ketty Lysie Libardi Lira Machado, Tania Queiroz Reuter Motta, Jaquelini Jubini, Carla Cristina Moraes de Mattos, Maria Angélica Calegário Vieira, Danielle Grillo Pacheco Lyra, Cristiano Soares da Silva, Rodrigo Ribeiro Rodrigues, Luís Carlos Reblin, Orlei Cardoso, Lely Stella Guzmán Barrera, Jhader Pércio, Ismael Artur da Costa Rocha, Roberta Oliveira Prado, Agnes Antônia Sampaio Pereira, Vitor Hugo Simões Miranda, Gláucia Diniz Alessio, Fernanda Fortes de Araújo, Elaine Speziali, Christiane Costa Pereira, Clarice Carvalho Alves, Kétyllen Reis Andrade de Carvalho, Anna Carolina Cançado Figueiredo, Liliane Martins dos Santos, Cristiana Couto Garcia, Nani Oliveira Carvalho, Laise Rodrigues Reis, Tâmilla Mayane Alves Fidelis dos Santos, Joaquim Pedro Brito-de-Souza, Camila Medeiros Costa, Isabela Natália Pascoal Campos do Vale, Priscilla Miranda Henriques, Poliane Silva Maciel, Thais Abdala Torres, Nathália Werneck Cézar de Oliveira, Gabriela de Oliveira, Luana Oliveira Borges Fernandes, Andreza Parreiras Gonçalves, Jesuanne Carla Silva Andrade, Ladson Lúcio Viana da Silva, Armanda Moreira Mattoso Barbosa, Maria Beatriz Martins Araújo, Bruna Luiza Fonte Boa Rocha, Lis Ribeiro do Valle Antonelli, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Waleska Dias Schwarcz, Nathalia dos Santos Alves, Ingrid Siciliano Horbach, Ariane Faria de Souza, Brenda de Moura Dias, Bruno Pimenta Setatino, Caio Bidueira Denani

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Fractional dose is an important strategy to increase access to vaccines. This study evaluated the effectiveness, safety, and immunogenicity of half dose of ChAdOx1 nCoV-19 vaccine. A non-inferiority non-randomized controlled trial compared a half dos

Externí odkaz: https://doaj.org/article/0906b38d59ab4e75add7bcfe17d13124

17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil

Autor: Olindo Assis Martins-Filho, Vanessa Peruhype-Magalhāes, Jordana Grazziela Coelho-dos-Reis, Lis Ribeiro Antonelli, Christiane Costa-Pereira, Elaine Speziali, Laise Rodrigues Reis, Jandira Aparecida Lemos, José Geraldo Leite Ribeiro, Luiz Antônio Bastos Camacho, Maria de Lourdes de Sousa Maia, Sheila Maria Barbosa de Lima, Marisol Simões, Reinaldo de Menezes Martins, Akira Homma, Luiz Cosme Cota Malaquias, Pedro Luiz Tauil, Pedro Fernando Costa Vasconcelos, Alessandro Pecego Martins Romano, Carla Magda Domingues, Andréa Teixeira-Carvalho, Ana Carolina Campi-Azevedo

Publikováno v: Emerging Infectious Diseases, Vol 25, Iss 8, Pp 1511-1521 (2019)

We evaluated the duration of neutralizing antibodies and the status of 17DD vaccine–specific T- and B-cell memory following primary and revaccination regimens for yellow fever (YF) in Brazil. We observed progressive decline of plaque-reduction neut

Externí odkaz: https://doaj.org/article/1b4bf57455084e988dd27f6a3148665b

Corrigendum: Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine

Autor: Ismael Artur da Costa-Rocha, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Jordana Grazziela Coelho-dos-Reis, Jordana Rodrigues Barbosa Fradico, Thalles Souza-Lopes, Laise Rodrigues Reis, Larissa Chaves Freire, Christiane Costa-Pereira, Juliana Vaz de Melo Mambrini, Maria de Lourdes de Sousa Maia, Sheila Maria Barbosa de Lima, Tatiana Guimarães de Noronha, Janaina Reis Xavier, Luiz Antonio Bastos Camacho, Elizabeth Maciel de Albuquerque, Roberto Henrique Guedes Farias, Thalita da Matta de Castro, Akira Homma, Alessandro Pecego Martins Romano, Carla Magda Domingues, Reinaldo de Menezes Martins, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Externí odkaz: https://doaj.org/article/d2d3af6e0b7243e8afba768857869f18

Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine

Autor: Ismael Artur da Costa-Rocha, Ana Carolina Campi-Azevedo, Vanessa Peruhype-Magalhães, Jordana Grazziela Coelho-dos-Reis, Jordana Rodrigues Barbosa Fradico, Thalles Souza-Lopes, Laise Rodrigues Reis, Larissa Chaves Freire, Christiane Costa-Pereira, Juliana Vaz de Melo Mambrini, Maria de Lourdes de Sousa Maia, Sheila Maria Barbosa de Lima, Tatiana Guimarães de Noronha, Janaina Reis Xavier, Luiz Antonio Bastos Camacho, Elizabeth Maciel de Albuquerque, Roberto Henrique Guedes Farias, Thalita da Matta de Castro, Akira Homma, Alessandro Pecego Martins Romano, Carla Magda Domingues, Reinaldo de Menezes Martins, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

The present study aims to determine whether 17DD-YF-specific humoral and cellular immunological memory is maintained 8-years after primary vaccination with subdoses (10,447IU;3,013IU;587IU;158IU;31IU). For this purpose, this follow-up study was carri

Externí odkaz: https://doaj.org/article/548103b52730423a9339b2897aec96d1

Multi-parameter approach to evaluate the timing of memory status after 17DD-YF primary vaccination.

Autor: Christiane Costa-Pereira, Ana Carolina Campi-Azevedo, Jordana Grazziela Coelho-Dos-Reis, Vanessa Peruhype-Magalhães, Márcio Sobreira Silva Araújo, Lis Ribeiro do Vale Antonelli, Cristina Toscano Fonseca, Jandira Aparecida Lemos, Luiz Cosme Cote Malaquias, Matheus de Souza Gomes, Laurence Rodrigues Amaral, Maria Rios, Caren Chancey, Harold Richard Persi, Jorge Marcelo Pereira, Maria de Lourdes de Sousa Maia, Marcos da Silva Freire, Reinaldo de Menezes Martins, Akira Homma, Marisol Simões, Anna Yoshida Yamamura, Roberto Henrique Guedes Farias, Alessandro Pecego Martins Romano, Carla Magda Domingues, Pedro Luiz Tauil, Pedro Fernando Costa Vasconcelos, Iramaya Rodrigues Caldas, Luiz Antônio Camacho, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 6, p e0006462 (2018)

In this investigation, machine-enhanced techniques were applied to bring about scientific insights to identify a minimum set of phenotypic/functional memory-related biomarkers for post-vaccination follow-up upon yellow fever (YF) vaccination. For thi

Externí odkaz: https://doaj.org/article/53d2be897f6340548ba15c77754aeb9f