Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christiane Chbib"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 184 (2024)
The molecule (S)-4,5-dihydroxy-2,3-pentanedione (DPD) is produced by many different species of bacteria and is involved in bacterial communication. DPD is the precursor of signal molecule autoinducer-2 (AI-2) and has high potential to be used as a va
Externí odkaz:
https://doaj.org/article/4bdb8558f164429b81860a8340865848
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 713 (2023)
Autoinducers AI-1 and AI-2 play an important role in bacterial quorum sensing (QS), a form of chemical communication between bacteria. The autoinducer N-octanoyl-L-Homoserinehomoserine lactone (C8-HSL) serves as a major inter- and intraspecies commun
Externí odkaz:
https://doaj.org/article/f5eec5a5cd4942bc9fa1454c62f75041
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1245 (2021)
Sexually transmitted diseases (STDs) are a major global health issue. Approximately 250 million new cases of STDs occur each year globally. Currently, only three STDs (human papillomavirus (HPV), hepatitis A, and hepatitis B) are preventable by vacci
Externí odkaz:
https://doaj.org/article/c9a9593b4fb84fd4b03c350c0db319e0
Publikováno v:
Antibiotics, Vol 8, Iss 1, p 30 (2019)
Objective: The objective of this review is to describe the outcomes of patients treated with ceftaroline in the non-Food and Drug Administration (FDA) approved indication of methicillin-resistant Staphylococcus aureus (MRSA) infections in both pediat
Externí odkaz:
https://doaj.org/article/f4abc5d1378b4333a28012c479dfbb68
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a00009784981168ce4f5472a39639ff1
https://doi.org/10.2139/ssrn.4062524
https://doi.org/10.2139/ssrn.4062524
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 1245, p 1245 (2021)
Vaccines, Vol 9, Iss 1245, p 1245 (2021)
Sexually transmitted diseases (STDs) are a major global health issue. Approximately 250 million new cases of STDs occur each year globally. Currently, only three STDs (human papillomavirus (HPV), hepatitis A, and hepatitis B) are preventable by vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3d886fd434cc5129e91777c7b191ee
https://pubmed.ncbi.nlm.nih.gov/34835176
https://pubmed.ncbi.nlm.nih.gov/34835176
Publikováno v:
The AAPS journal. 23(4)
Adjuvants potentiate the immune response against co-inoculated antigens in the vaccine formulation. Based on the mechanism of action, the adjuvants are classified as immunostimulatory adjuvants and vaccine delivery systems. (S)-4,5-Dihydroxy-2,3-pent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e7fe6d7fe00e2277239277c922a96e
https://pubmed.ncbi.nlm.nih.gov/34131810
https://pubmed.ncbi.nlm.nih.gov/34131810
Autor:
Christiane Chbib
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:1681-1685
LuxS (S-ribosylhomocysteinase; EC 4.4.1.21) is an enzyme that catalyzes the cleavage of the thioether linkage in the catalytic pathway of S-ribosylhomocysteine (SRH) which produces homocysteine and 4,5-dihydroxy-2,3-pentanedione (DPD). DPD is the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b1e4db2c0c3fcbd0bdb6e96f1ff2cb
https://doi.org/10.1016/j.bmcl.2017.03.004
https://doi.org/10.1016/j.bmcl.2017.03.004
Autor:
Christiane Chbib
Publikováno v:
Bioorganicmedicinal chemistry. 28(3)
With the emergence of microbial resistance pathogens, recent research aims at studying new mechanisms of action of antibiotics. This review discusses the mechanisms and types of quorum sensing (QS) inhibitors in Gram negative bacteria. It illustrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44f47e703d3ec4b965d0317fb7342bb
https://pubmed.ncbi.nlm.nih.gov/31918952
https://pubmed.ncbi.nlm.nih.gov/31918952