Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Christiane Bousquet"'
Autor:
Lisette Lagacé, Daniel Lamarre, Roger Maurice, Rock Gingras, Diane Thibeault, Christiane Bousquet, Peter W. White
Publikováno v:
Journal of Virology. 78:7352-7359
Hepatitis C virus (HCV) displays a high degree of genetic variability. Six genotypes and more than 50 subtypes have been identified to date. In this report, kinetic profiles were determined for NS3 proteases of genotypes 1a, 1b, 2ac, 2b, and 3a, reve
Autor:
Michel Garneau, Michael G. Cordingley, Gordon Bolger, Christiane Bousquet, Philip Kibler, François Tremblay
Publikováno v:
Antiviral Research. 59:193-200
The purpose of these studies was to investigate the use of non-invasive electroretinography for the evaluation of retinal disease and its treatment in an ocular murine cytomegalovirus (MCMV) disease model. While under anesthesia, 10(2.6)plaque formin
Autor:
Manon Rhéaume, Gordon Bolger, Christiane Bousquet, Nicole Lapeyre, Michel Garneau, Philip Kibler, Michael G. Cordingley
Publikováno v:
Antiviral Research. 44:155-165
Acute intraperitoneal infection of weanling BALB/c mice with murine cytomegalovirus (MCMV) resulted in an inoculum titer-dependent weight loss, mortality and elevation of plasma transaminases (ALT: alanine transaminase and AST: aspartate transaminase
Autor:
Nathalie Dansereau, Christiane Bousquet, A M Bonneau, Philip Kibler, Michael G. Cordingley, Peter W. White
Publikováno v:
Journal of Virology. 70:787-793
Herpes simplex virus (HSV) encodes its own ribonucleotide reductase (RR), which provides the high levels of deoxynucleoside triphosphates required for viral DNA replication in infected cells. HSV RR is composed of two distinct subunits, R1 and R2, wh
Autor:
Catherine Spickler, Diane Thibeault, Marie-Josée Massariol, Ibtissem Triki, Christiane Bousquet, Montse Llinas-Brunet, George Kukolj, Peter W. White, Martin Marquis, Nathalie Dansereau, Florence Dô, Roger Maurice, Lisette Lagacé, Songping Zhao
Publikováno v:
Antimicrobial agents and chemotherapy. 56(1)
The in vitro resistance profile of BI 201335 was evaluated through selection and characterization of variants in genotype 1a (GT 1a) and genotype 1b (GT 1b) replicons. NS3 R155K and D168V were the most frequently observed resistant variants. Phenotyp
Autor:
Philip Kibler, Christiane Bousquet, Bruno Simoneau, Michel Garneau, Robert S. McCollum, Michael G. Cordingley, Gordon Bolger, Fayaz Harji, Anne-Marie Faucher, Nicole Lapeyre, Michel Liuzzi
Publikováno v:
Antiviral research. 64(3)
The aminothiazolylphenyl-containing compounds BILS 179 BS and BILS 45 BS are novel inhibitors of the herpes simplex virus helicase-primase with antiviral activity in vitro and in animal models of HSV disease. To verify the mechanism of antiviral acti
Autor:
Christiane Bousquet, William Paris, Michel Liuzzi, Jianmin Duan, Michael G. Cordingley, Philip Kibler
Publikováno v:
Antiviral research. 39(3)
The present study investigates the full dose-response curve and treatment duration dependence of ganciclovir (GCV) against murine cytomegalovirus (MCMV) infection in severe combined immunodeficiency (SCID) mice. Animals inoculated intraperitoneally w
Autor:
Michel Garneau, Nell Moss, Yvan Guindon, Michel Liuzzi, Christiane Bousquet, Robert Deziel, Lisette Lagacé, Richard Krogsrud, Pierre L. Beaulieu, Anne-Marie Bonneau, James G. Chafouleas, Jorge Jaramillo, Robert S. McCollum, Sopone Nawoot
Publikováno v:
Nature. 372(6507)
Herpes simplex viruses (HSV) types 1 and 2 encode their own ribonucleotide reductases (RNRs) (EC 1.17.4.1) to convert ribonucleoside diphosphates into the corresponding deoxyribonucleotides. Like other iron-dependent RNRs, the viral enzyme is formed
Autor:
Peter W. White, Diane Thibeault, Daniel Lamarre, Rock Gingras, Christiane Bousquet, Roger Maurice, Lisette Lagacé
Publikováno v:
Hepatology. 38:300-300
Autor:
Michael G. Cordingley, William Paris, Christiane Bousquet, Jianmin Duan, Michel Liuzzi, Philip Kibler
Publikováno v:
Antiviral Research. 34:A84