Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Christiane Amendt"'
Autor:
Steffie Revia, Felix Neumann, Julia Jabs, Florian Orio, Christian Sirrenberg, Astrid Zimmermann, Christiane Amendt, Joachim Albers
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5120 (2024)
Triple-negative breast cancer (TNBC) remains the most lethal subtype of breast cancer, characterized by poor response rates to current chemotherapies and a lack of additional effective treatment options. While approximately 30% of patients respond we
Externí odkaz:
https://doaj.org/article/8f3b1449f0f54b269940a3f1398efdd0
Autor:
Steffie Revia, Magdalena A. Budzinska, Olga Bogatyrova, Felix Neumann, Astrid Zimmermann, Christiane Amendt, Joachim Albers
Publikováno v:
Cancers, Vol 16, Iss 1, p 189 (2023)
Synovial sarcoma is a rare and highly aggressive subtype of soft tissue sarcoma. The clinical challenge posed by advanced or metastatic synovial sarcoma, marked by limited treatment options and suboptimal outcomes, necessitates innovative approaches.
Externí odkaz:
https://doaj.org/article/7bfd18e9dd374e539d57304898bf680a
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Christiane Amendt, Thomas Fuchss, Claudia Wilm, Thomas Grombacher, Ulrich Pehl, Vladimir Kirkin, Heike Dahmen, Christian Sirrenberg, Astrid Zimmermann, Frank T. Zenke
Physical and chemical DNA-damaging agents are used widely in the treatment of cancer. Double-strand break (DSB) lesions in DNA are the most deleterious form of damage and, if left unrepaired, can effectively kill cancer cells. DNA-dependent protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da0e55c5d046814765f05ef007fff9a
https://doi.org/10.1158/1535-7163.c.6542803.v1
https://doi.org/10.1158/1535-7163.c.6542803.v1
Autor:
Andree Blaukat, Lyubomir T. Vassilev, Christiane Amendt, Thomas Fuchss, Claudia Wilm, Thomas Grombacher, Ulrich Pehl, Vladimir Kirkin, Heike Dahmen, Christian Sirrenberg, Astrid Zimmermann, Frank T. Zenke
Supplementary Table S1: Evaluation of M3814 (MSC2490484) in kinase assays Supplementary Table S2: In vitro activity of M3814 in combination with a single dose of gamma radiation in a panel of 93 cell lines. Supplementary Table S3: Pharmacokinetic dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e3c3f062536172fc64c7760da99e54
https://doi.org/10.1158/1535-7163.22520839
https://doi.org/10.1158/1535-7163.22520839
Autor:
Timothy J. Mitchison, Frank T. Zenke, Claudia Wilm, Christiane Amendt, Clement T. Loy, Jade Shi, Yangzhong Tang, James D. Orth
Supplementary Fig. S1 from Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0595d9ccc193c5c4dd6436ba0d3685f7
https://doi.org/10.1158/1535-7163.22483554
https://doi.org/10.1158/1535-7163.22483554
Autor:
Timothy J. Mitchison, Frank T. Zenke, Claudia Wilm, Christiane Amendt, Clement T. Loy, Jade Shi, Yangzhong Tang, James D. Orth
Supplementary Methods from Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f4016373736a2af88b93a483de1380
https://doi.org/10.1158/1535-7163.22483524
https://doi.org/10.1158/1535-7163.22483524
Autor:
Timothy J. Mitchison, Frank T. Zenke, Claudia Wilm, Christiane Amendt, Clement T. Loy, Jade Shi, Yangzhong Tang, James D. Orth
Supplementary Table S3 from Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4404bcc724ec46d0dc423beee96d7d8a
https://doi.org/10.1158/1535-7163.22483515
https://doi.org/10.1158/1535-7163.22483515
Purpose: To explore in a panel of patient-derived xenograft models of human non–small cell lung cancer (NSCLC) whether high EGFR expression, was associated with cetuximab activity.Experimental Design: NSCLC patient-derived xenograft models (n = 45)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b512d2709a602523a20a398f27cfe29
https://doi.org/10.1158/1078-0432.c.6522747.v1
https://doi.org/10.1158/1078-0432.c.6522747.v1
Autor:
Timothy J. Mitchison, Frank T. Zenke, Claudia Wilm, Christiane Amendt, Clement T. Loy, Jade Shi, Yangzhong Tang, James D. Orth
Kinesin-5 inhibitors (K5I) are promising antimitotic cancer drug candidates. They cause prolonged mitotic arrest and death of cancer cells, but their full range of phenotypic effects in different cell types has been unclear. Using time-lapse microsco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7458dcb870e35eaa46251de3f99e9798
https://doi.org/10.1158/1535-7163.c.6531162
https://doi.org/10.1158/1535-7163.c.6531162
Table S2. Mann-Whitney test P-values relating to the differences in log2 tumor/control ratios at week 3 for cetuximab monotherapy/control and cisplatin plus cetuximab/cisplatin alone between tumors with low and high EGFR expression as determined by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04024d40eb7762cb5df6a8741b608e59
https://doi.org/10.1158/1078-0432.22454436.v1
https://doi.org/10.1158/1078-0432.22454436.v1