Prognostic role of HPV integration status and molecular profile in advanced anal carcinoma: An ancillary study to the epitopes-HPV02 trial

Autor: Alice Debernardi, Aurélia Meurisse, Jean-Luc Prétet, David Guenat, Franck Monnien, Laurie Spehner, Angélique Vienot, Patrick Roncarati, Thierry André, Laurent Abramowitz, Chloé Molimard, Christiane Mougin, Michael Herfs, Stefano Kim, Christophe Borg

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Squamous Cell Carcinoma of the Anal canal (SCCA) is a rare disease associated with a Human Papillomavirus (HPV) infection in most cases, predominantly the HPV16 genotype. About 15% of SCCA are diagnosed in metastatic stage and some will relapse after

Externí odkaz: https://doaj.org/article/7ae7ddd728064f5fa3ee2a3a4e2107d0

Development and interlaboratory agreement of real-time PCR for HPV16 quantification in liquid-based cervical samples

Autor: David Guenat, Véronique Dalstein, Frédéric Mauny, Maëlle Saunier, Jenny Briolat, Christine Clavel, Didier Riethmuller, Christiane Mougin, Jean-Luc Prétet

Publikováno v: Papillomavirus Research, Vol 6, Iss , Pp 27-32 (2018)

High risk HPV infection is the necessary cause for the development of precancerous and cancerous lesions of the cervix. Among HPV, HPV16 represents the most carcinogenic type. Since the determination of HPV16 DNA load could be clinically useful, we a

Externí odkaz: https://doaj.org/article/d5b714ee56d64ae0813b9a7b42363c22

Prevalence and risk factors of human papillomavirus infection types 16/18/45 in a cohort of French females aged 15–23 years

Autor: Ariane Baudu, Jean-Luc Prétet, Didier Riethmuller, Morgane Chotard, Christiane Mougin, Mariette Mercier

Publikováno v: Journal of Epidemiology and Global Health, Vol 4, Iss 1 (2019)

Investigation of the prevalence and risk factors of human papillomavirus (HPV) infection is the basis for developing prophylactic strategies against cervical cancer, especially for young women. This study aimed to assess the prevalence and risk facto

Externí odkaz: https://doaj.org/article/0f4de835dad6419992c8d605f243e517

Human papillomavirus DNA and p16 expression in head and neck squamous cell carcinoma in young French patients

Autor: Christiane Mougin, Alexis Overs, Marie-Paule Algros, Christine Soret, David Guenat, Jean-Luc Prétet, Olivier Mauvais, Virginie L'Huillier, Chloé Molimard

Publikováno v: Journal of International Medical Research, Vol 49 (2021)
The Journal of International Medical Research

Objectives Human papillomavirus (HPV) is a risk factor for head and neck squamous cell carcinoma (HNSCC), which is currently increasing worldwide. We evaluated the prevalence of HPV DNA and p16 expression in HNSCC patients age Methods Thirty-nine pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09c9922b055995d85e0e7d084bab49b
https://doaj.org/article/66be148dc88e4cf1a375ca0c66608030

Repurposing the Hybrid Capture 2 (HC2) screening test for whole-genome sequencing of human papillomaviruses

Autor: Christiane Mougin, Q. Lepiller, Ignacio G. Bravo, A. Debernardi, C Soret, Jean-Luc Prétet, Samuel Alizon, W. Jarassier, D. Guenat

Publikováno v: Archives of Virology
Archives of Virology, 2021, 166 (12), pp.3421-3425. ⟨10.1007/s00705-021-05259-9⟩
Archives of Virology, Springer Verlag, 2021, ⟨10.1007/s00705-021-05259-9⟩

International audience; Simple and standardized approaches for genome analysis of human papillomavirus (HPV) by next-generation sequencing are needed. The aim of the study was to develop a protocol for direct deep sequencing of high-risk (hr) HPV str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996bee31353ce3efb1d99404f1a62586
https://hal.science/hal-03425708/file/DebernardiEtal2021.pdf