Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Christiane, Klec"'
Autor:
Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Barbara Pasculli, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondrej Slaby, Christiane Klec, Martin Pichler
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-17 (2023)
Abstract Background Triple negative breast cancer (TNBC) is a particularly aggressive and difficult-to-treat subtype of breast cancer that requires the development of novel therapeutic strategies. To pave the way for such developments it is essential
Externí odkaz:
https://doaj.org/article/d088562194214dca97084323852b7d66
Autor:
Felix Prinz, Katharina Jonas, Amar Balihodzic, Christiane Klec, Andreas Reicher, Dominik Andreas Barth, Jakob Riedl, Armin Gerger, Tobias Kiesslich, Christian Mayr, Beate Rinner, Julia Kargl, Martin Pichler
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1305-1315 (2022)
The microRNA-200 family has wide-ranging regulatory functions in cancer development and progression. Above all, it is strongly associated with the epithelial-to-mesenchymal transition (EMT), a process during which cells change their epithelial to a m
Externí odkaz:
https://doaj.org/article/9edcfdbbce2f49dc9ef762600d2aaea8
Autor:
Dominik A. Barth, Stefanie Stanzer, Jasmin Spiegelberg, Thomas Bauernhofer, Gudrun Absenger, Florian Posch, Rainer Lipp, Michael Halm, Joanna Szkandera, Marija Balic, Armin Gerger, Maria A. Smolle, Georg C. Hutterer, Christiane Klec, Philipp J. Jost, Julia Kargl, Martin Stradner, Martin Pichler
Publikováno v:
Cancer Medicine, Vol 11, Iss 16, Pp 3074-3083 (2022)
Abstract Background The presence of autoantibodies in the serum of cancer patients has been associated with immune‐checkpoint inhibitor (ICI) therapy response and immune‐related adverse events (irAEs). A prospective evaluation of different autoan
Externí odkaz:
https://doaj.org/article/8914eb1a50484886b516dc8999f59708
Autor:
Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondrej Slaby, Christiane Klec, Martin Pichler
Publikováno v:
Non-Coding RNA, Vol 10, Iss 1, p 2 (2023)
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression, and their deregulation contributes to many aspects of cancer development and progression. Thus, miRNAs provide insight into oncogenic mechanisms and represent promisin
Externí odkaz:
https://doaj.org/article/b8abed994f604fbea7adefc447d9a49c
Autor:
Dominik A. Barth, Stefanie Stanzer, Jasmin A. Spiegelberg, Thomas Bauernhofer, Gudrun Absenger, Joanna Szkandera, Armin Gerger, Maria A. Smolle, Georg C. Hutterer, Sascha A. Ahyai, Tobias Madl, Florian Posch, Jakob M. Riedl, Christiane Klec, Philipp J. Jost, Julia Kargl, Martin H. Stradner, Martin Pichler
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundImmune checkpoint inhibitors (ICIs) have revolutionized systemic anti-tumor treatments across different types of cancer. Nevertheless, predictive biomarkers regarding treatment response are not routinely established yet. Apart from T-lympho
Externí odkaz:
https://doaj.org/article/1c7e71b457324a089d3b19334f744c70
Autor:
Christiane Klec, Corina T. Madreiter-Sokolowski, Gabriela Ziomek, Sarah Stryeck, Vinay Sachdev, Madalina Duta-Mare, Benjamin Gottschalk, Maria R. Depaoli, Rene Rost, Jesse Hay, Markus Waldeck-Weiermair, Dagmar Kratky, Tobias Madl, Roland Malli, Wolfgang F. Graier
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 3, Pp 573-586 (2019)
Externí odkaz:
https://doaj.org/article/ecefd430b6a34c7c87fe3eda572a590f
Autor:
Benjamin Gottschalk, Christiane Klec, Gerd Leitinger, Eva Bernhart, René Rost, Helmut Bischof, Corina T. Madreiter-Sokolowski, Snježana Radulović, Emrah Eroglu, Wolfgang Sattler, Markus Waldeck-Weiermair, Roland Malli, Wolfgang F. Graier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitoch
Externí odkaz:
https://doaj.org/article/6ac9bbcf957c4a56ad8f56403898e532
Autor:
Daniela Schwarzenbacher, Christiane Klec, Barbara Pasculli, Stefanie Cerk, Beate Rinner, Michael Karbiener, Cristina Ivan, Raffaela Barbano, Hui Ling, Annika Wulf-Goldenberg, Stefanie Stanzer, Gabriel Rinnerthaler, Herbert Stoeger, Thomas Bauernhofer, Johannes Haybaeck, Gerald Hoefler, Stephan Wenzel Jahn, Paola Parrella, George Adrian Calin, Martin Pichler
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background Non-coding RNAs and especially microRNAs have been discovered to act as master regulators of cancer initiation and progression. The aim of our study was to discover and characterize the function of yet functionally uncharacterized
Externí odkaz:
https://doaj.org/article/2752cf158c34450c82e06d6e38fa5e14
Autor:
Christiane Klec, Corina T. Madreiter-Sokolowski, Sarah Stryeck, Vinay Sachdev, Madalina Duta-Mare, Benjamin Gottschalk, Maraia R. Depaoli, Rene Rost, Jesse Hay, Markus Waldeck-Weiermair, Dagmar Kratky, Tobias Madl, Roland Malli, Wolfgang F. Graier
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 1, Pp 57-75 (2019)
Externí odkaz:
https://doaj.org/article/78f4f083aaec4f7ebb83fc76ae62abe2
Autor:
Corina T. Madreiter-Sokolowski, Markus Waldeck-Weiermair, Marie-Pierre Bourguignon, Nicole Villeneuve, Benjamin Gottschalk, Christiane Klec, Sarah Stryeck, Snjezana Radulovic, Warisara Parichatikanond, Saša Frank, Tobias Madl, Roland Malli, Wolfgang F. Graier
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 458-466 (2019)
Background: Senescence is characterized by a gradual decline in cellular functions, including changes in energy homeostasis and decreased proliferation activity. As cellular power plants, contributors to signal transduction, sources of reactive oxyge
Externí odkaz:
https://doaj.org/article/f1455c7fc7a64f4581c789ca027a95e2