Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Christiana Iwuagwu"'
Autor:
Linda J Bristow, Amy E Easton, Yu-Wen Li, Digavalli V Sivarao, Regina Lidge, Kelli M Jones, Debra Post-Munson, Christopher Daly, Nicholas J Lodge, Lizbeth Gallagher, Thaddeus Molski, Richard Pieschl, Ping Chen, Adam Hendricson, Ryan Westphal, James Cook, Christiana Iwuagwu, Daniel Morgan, Yulia Benitex, Dalton King, John E Macor, Robert Zaczek, Richard Olson
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159996 (2016)
The development of alpha7 nicotinic acetylcholine receptor agonists is considered a promising approach for the treatment of cognitive symptoms in schizophrenia patients. In the present studies we characterized the novel agent, (2R)-N-(6-(1H-imidazol-
Externí odkaz:
https://doaj.org/article/cb2d80cbb97446c297511d2d30823d16
Autor:
Eric P. Gillis, Kyle Parcella, Michael Bowsher, James H. Cook, Christiana Iwuagwu, B. Narasimhulu Naidu, Manoj Patel, Kevin Peese, Haichang Huang, Lourdes Valera, Chunfu Wang, Kasia Kieltyka, Dawn D. Parker, Jean Simmermacher, Eric Arnoult, Robert T. Nolte, Liping Wang, John A. Bender, David B. Frennesson, Mark Saulnier, Alan Xiangdong Wang, Nicholas A. Meanwell, Makonen Belema, Umesh Hanumegowda, Susan Jenkins, Mark Krystal, John F. Kadow, Mark Cockett, Robert Fridell
Publikováno v:
Journal of Medicinal Chemistry. 66:1941-1954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec60862845d7a9e3c5ea18ee8c48c091
https://doi.org/10.1021/acs.jmedchem.2c01732
https://doi.org/10.1021/acs.jmedchem.2c01732
Autor:
Jeffrey Shapiro, Bullock William H, Christine Keiper, Manami Tsutsumi, Ling Yang, Roger B Clark, Xin Ma, Sidney X. Liang, James N. Livingston, Louis-David Cantin, Christiana Iwuagwu, Frederick Ehrgott, Jeffrey Johnson, Thomas H. Claus, Ken Boakye, Herbert Ogutu, Christopher Town, Michael Burns, Michelle Daly, Robert Schoenleber, Fernando E. delaCruz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:1056-1061
Modulation of PPAR activities represents an attractive approach for the treatment of diabetes with associated cardiovascular complications. The indanylacetic acid structural motif has proven useful in the generation of potent and tunable PPAR ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9a4acbce2e5d8ca51dd1dff7df78ef5
https://doi.org/10.1016/j.bmcl.2006.11.025
https://doi.org/10.1016/j.bmcl.2006.11.025
Autor:
Manami Tsutsumi, Rico C. Lavoie, James N. Livingston, Frederick Ehrgott, Laurel Sweet, Herbert Ogutu, Steve Magnuson, Tatiana E. Shelekhin, Philip Wickens, Jeff Shapiro, Qian Zhao, Robert Schoenleber, Louis-David Cantin, Bullock William H, John Amatruda, Sidney X. Liang, Fernando Dela Cruz, Ellalahewage Kumarasinghe, David Ladner, Thomas H. Claus, Miao Dai, Christopher Town, Chengzhi Zhang, Derek B. Lowe, Martin F. Hentemann, Michael Burns, Sarah Heald, Jeffrey Johnson, Gretchen Mannelly, Susan Pleasic-Williams, Mugge Ingo A, Chih-Yuan Chuang, Dongping Fan, David P. Dickson, Xin Ma, Christiana Iwuagwu
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(15)
A series of indane acetic acid derivatives were prepared which show a spectrum of activity as insulin sensitizers and PPAR-alpha and PPAR-delta ligands. In vivo data are presented for insulin sensitizers with selectivity for PPAR-delta over PPAR-alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcd0d05dddd6e859b60d88722dc5ea1
https://pubmed.ncbi.nlm.nih.gov/17601734
https://pubmed.ncbi.nlm.nih.gov/17601734