Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christiana Brenin"'
Autor:
Trish Millard, Christiana Brenin, Clare Humphrey, Ajay Dhakal, Carla Falkson, Gina Petroni, Nolan A. Wages, Patrick Dillon
Publikováno v:
International Journal of Breast Cancer, Vol 2024 (2024)
Background. Breast cancer has an unacceptably high recurrence rate when any residual disease is found following neoadjuvant treatment of high-risk disease. Based on clinical data suggesting an adjuvant role for epigenetic modifying agents in breast c
Externí odkaz:
https://doaj.org/article/e556c909175542cbad156cca57b31b4d
Publikováno v:
Case Reports in Oncological Medicine, Vol 2019 (2019)
Metastatic carcinomatosis to the liver is a pattern of malignant infiltration that tends to provoke hepatic fibrosis. It is a rare complication of multiple solid tumor types and often seen in the absence of discrete tumor mass in the liver. We report
Externí odkaz:
https://doaj.org/article/4f9055010a8f41bd94c63646dd9b5ac4
Publikováno v:
Cancer Research. 83:PD16-05
Introduction Per NCCN guidelines, patients with stage I-III breast cancer should only have staging work up with CT chest, abdomen, and pelvis and bone scan if there are concerning symptoms, lab abnormalities, or physical exam findings. These patients
Publikováno v:
Breast Cancer: Targets and Therapy. 12:69-75
Vaccine therapies for treatment and prevention of cancer have seen modest degrees of efficacy with wide variation related to the tumor type, vaccine type, adjuvants and clinical setting for their study. Over the course of the last two decades, variou
Publikováno v:
Cancer Research. 79:OT1-05
Background: HDAC inhibitors (HDACi) upregulate thymidine phosphorylase resulting in enhanced conversion of capecitabine to active 5-fluorouracil and in synergistic anti-proliferative effects. HDACi's down regulate thymidine synthase and may prevent r
Autor:
Mark E. Smolkin, Carmel Nail, David R. Brenin, Patrick M. Dillon, Kimberly A. Chianese-Bullock, Craig L. Slingluff, Ibrahim Fanous, Gina R. Petroni, Christiana Brenin, Walter C. Olson, Emily H. Hall, Kelly T. Smith
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-10 (2017)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Breast cancer remains a leading cause of cancer death worldwide. There is evidence that immunotherapy may play a role in the eradication of residual disease. Peptide vaccines for immunotherapy are capable of durable immune memory, but vacc
Publikováno v:
Case Reports in Oncological Medicine, Vol 2019 (2019)
Case Reports in Oncological Medicine
Case Reports in Oncological Medicine
Metastatic carcinomatosis to the liver is a pattern of malignant infiltration that tends to provoke hepatic fibrosis. It is a rare complication of multiple solid tumor types and often seen in the absence of discrete tumor mass in the liver. We report
Publikováno v:
Journal of Clinical Oncology. 36:2743-2744
Autor:
Erin R. Yarde, Michael Naughton, Cynthia X. Ma, Paula M. Fracasso, Philip S. Bernard, Gina R. Petroni, Shi Rong Cai, Timothy J. Pluard, Joel Picus, Matthew J. Ellis, Jerry S. Reed, Mark A. Watson, Laurence A. Doyle, Janet Dancey, Allison N. Creekmore, Tibu Mwandoro, Helen Piwnica-Worms, Christine E. Ryan, A. Craig Lockhart, Zhanfang Guo, Christiana Brenin, Mark T. W. Ebbert
Publikováno v:
Breast Cancer Research and Treatment
Mutations in TP53 lead to a defective G1 checkpoint and the dependence on checkpoint kinase 1 (Chk1) for G2 or S phase arrest in response to DNA damage. In preclinical studies, Chk1 inhibition resulted in enhanced cytotoxicity of several chemotherape
Autor:
Patrick M. Dillon, Christiana Brenin, Bethany J. Horton, David R. Brenin, Timothy N. J. Bullock
Publikováno v:
Journal of Clinical Oncology. 36:TPS19-TPS19
TPS19 Background: Focused ultrasound (FUS) is an ablative therapy which can heat tumors rapidly to cell damaging temperatures and simultaneously perturb the microenvironment, the microvasculature, and the lymphatics. At typical energy levels, FUS can