Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Christiana, Leimena"'
Autor:
Ning Zhou, Xin Chen, Jing Xi, Ben Ma, Christiana Leimena, Shaunrick Stoll, Gangjian Qin, Charles Wang, Hongyu Qiu
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101662- (2020)
Chronic hypertension is a key risk factor for heart failure. However, the underlying molecular mechanisms are not fully understood. Our previous studies found that the valosin-containing protein (VCP), an ATPase-associated protein, was significantly
Externí odkaz:
https://doaj.org/article/9688fec305584676a3fa3f615db7c46c
Autor:
Georg Vogler, Diane Fatkin, Katja Birker, Christiana Leimena, Ann-Kristin Altekoester, Peter C. M. Molenaar, Karen Ocorr, David G. Allen, Richard P. Harvey, Halina Dobrzynski, Inken G. Huttner, Arie Jacoby, Magdalena Soka, Renee Johnson, Andrew Atkinson, Vesna Nikolova-Krstevski, Adam P. Hill, Rolf Bodmer, Yue-Kun Ju, Sreehari Kalvakuri, Santiago Pineda, Dirk F. van Helden, Charles D. Cox, Dennis L. Kuchar, Monique Ohanian, Gunjan Trivedi
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
Background: KCNMA1 encodes the α-subunit of the large-conductance Ca 2+ -activated K + channel, K Ca 1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K Ca 1.1 are limited, and KCNMA1 has no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01612d0422981dad9c335de2df839668
https://doi.org/10.1161/circgen.120.003144
https://doi.org/10.1161/circgen.120.003144
Autor:
Santiago, Pineda, Vesna, Nikolova-Krstevski, Christiana, Leimena, Andrew J, Atkinson, Ann-Kristin, Altekoester, Charles D, Cox, Arie, Jacoby, Inken G, Huttner, Yue-Kun, Ju, Magdalena, Soka, Monique, Ohanian, Gunjan, Trivedi, Sreehari, Kalvakuri, Katja, Birker, Renee, Johnson, Peter, Molenaar, Dennis, Kuchar, David G, Allen, Dirk F, van Helden, Richard P, Harvey, Adam P, Hill, Rolf, Bodmer, Georg, Vogler, Halina, Dobrzynski, Karen, Ocorr, Diane, Fatkin
Publikováno v:
Circ Genom Precis Med
BACKGROUND: KCNMA1 encodes the α-subunit of the large-conductance Ca(2+)-activated K(+) channel, K(Ca)1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K(Ca)1.1 are limited, and KCNMA1 has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::945820691bcdde1e027da6e9bb57eee1
https://pubmed.ncbi.nlm.nih.gov/33629867
https://pubmed.ncbi.nlm.nih.gov/33629867
Autor:
Ning Zhou, Jing Xi, Gangjian Qin, Charles Wang, Shaunrick Stoll, Christiana Leimena, Xin Chen, Hongyu Qiu, Ben Ma
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Pressure overload-induced cardiac hypertrophy, such as that caused by hypertension, is a key risk factor for heart failure. However, the underlying molecular mechanisms remain largely unknown. We previously reported that the valosin-containing protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff8aa338e2662f1612f8f65abbd1357
http://europepmc.org/articles/PMC7582185
http://europepmc.org/articles/PMC7582185
Autor:
Santiago Pined, David G. Allen, Dirk F. van Helden, Sreehari Kalvakuri, Halina Dobrzyn, Christiana Leimena, Renee Johnson, Andrew Atkinson, Richard P. Harvey, Diane Fatkin, Gunjan Trived, Ann-Kristin Altekoester, Karen Ocorr, Peter C. M. Molenaar, Arie Jacoby, Charles D. Cox, Dennis L. Kuchar, Rolf Bodmer, Monique Ohanian, Inken G. Huttner, Georg Vogler, Magdalena Soka, Vesna Nikolova-Krstevski, Yue-Kun Ju, Adam P. Hill
BackgroundKCNMA1 encodes the α-subunit of the large-conductance Ca2+-activated K+ channel, KCa1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of KCa1.1 are limited and KCNMA1 has not been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d38efcb107ad676586738e523b836b
https://doi.org/10.1101/2020.06.28.176495
https://doi.org/10.1101/2020.06.28.176495
Autor:
Christiana Leimena, Shaunrick Stoll, Xin Chen, Hongyu Qiu, Ben Ma, Ning Zhou, Jing Xi, Gangjian Qin, Charles Wang
Publikováno v:
Redox Biology
Redox Biology, Vol 36, Iss, Pp 101662-(2020)
Redox Biology, Vol 36, Iss, Pp 101662-(2020)
Chronic hypertension is a key risk factor for heart failure. However, the underlying molecular mechanisms are not fully understood. Our previous studies found that the valosin-containing protein (VCP), an ATPase-associated protein, was significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230d219def224e98bf0f1541cdb12efd
https://pubmed.ncbi.nlm.nih.gov/32795937
https://pubmed.ncbi.nlm.nih.gov/32795937
Autor:
Jing Xi, Shaunrick Stoll, Ben Ma, Hongyu Qiu, Gangjian Qin, Christiana Leimena, Erik J. Behringer
Publikováno v:
Toxicol Sci
Stress-induced mitochondrial calcium (Ca2+) overload is a key cellular toxic effectors and a trigger of cardiomyocyte death during cardiac ischemic injury through the opening of mitochondrial permeability transition pore (mPTP). We previously found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35ce8c90788f7f0fc615c3a07033bdd
https://pubmed.ncbi.nlm.nih.gov/31368507
https://pubmed.ncbi.nlm.nih.gov/31368507
Publikováno v:
Muscle Cell and Tissue-Current Status of Research Field
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b4864e540a20f57f421065809f9dfc
http://www.intechopen.com/articles/show/title/vascular-smooth-muscle-cell
http://www.intechopen.com/articles/show/title/vascular-smooth-muscle-cell
Publikováno v:
Mitochondrial Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe12e06aaf0eb4a4f0d1b9a795cc524c
https://doi.org/10.5772/intechopen.72611
https://doi.org/10.5772/intechopen.72611
Autor:
Christiana Leimena, Hongyu Qiu
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 927 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Hypertension is a complex, multifactorial disease that involves the coexistence of multiple risk factors, environmental factors and physiological systems. The complexities extend to the treatment and management of hypertension, which are still the pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e6efd1cd452fc4c9b5afa5307033c8
http://www.mdpi.com/1422-0067/19/4/927
http://www.mdpi.com/1422-0067/19/4/927