Age-related impairments and influence of visual feedback when learning to stand with unexpected sensorimotor delays

Autor: Brandon G. Rasman, Christian van der Zalm, Patrick A. Forbes

Publikováno v: Frontiers in Aging Neuroscience, Vol 15 (2023)

BackgroundWhile standing upright, the brain must accurately accommodate for delays between sensory feedback and self-generated motor commands. Natural aging may limit adaptation to sensorimotor delays due to age-related decline in sensory acuity, neu

Externí odkaz: https://doaj.org/article/5eae4efdb89d4243a48ce0898e251813

Activated PI3Kδ syndrome, an immunodeficiency disorder, leads to sensorimotor deficits recapitulated in a murine model

Autor: Sandra M. Arend, Izi Izumi Floriano, P. Martin van Hagen, Aleksandra Badura, Ines Serra, Johan J.M. Pel, Olivia R. Manusama, Virgil A. S. H. Dalm, Fabian M.P. Kaiser, Christian van der Zalm, Klaus Okkenhaug, Nico J.M. van Beveren, Hanna IJspeert, Lucas Wahl

Publikováno v: Brain, Behavior, & Immunity-Health, Vol 18, Iss, Pp 100377-(2021)
Brain, behavior, & immunity-health, 18:100377. Elsevier Inc.
Brain, Behavior, & Immunity-Health

The phosphoinositide-3-kinase (PI3K) family plays a major role in cell signalling and is predominant in leukocytes. Gain-of-function (GOF) mutations in the PIK3CD gene lead to the development of activated PI3Kδ syndrome (APDS), a rare primary immuno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef066d6af7eda61a9ddca19fb022ef35