Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Christian Wesslau"'
Publikováno v:
Biochemical and Biophysical Research Communications. 301:578-582
Peroxisome proliferator-activated receptor gamma (PPAR gamma) co-activator 1 (PGC-1) regulates glucose metabolism and energy expenditure and, thus, potentially insulin sensitivity. We examined the expression of PGC-1, PPAR gamma, insulin receptor sub
Autor:
Håkan Olausson, Björn Eliasson, B. Gunnar Wallin, Ulf Norrsell, Martin Frizell, Christian Wesslau
Publikováno v:
Muscle & Nerve. 24:1496-1502
Five different procedures used to diagnose neuropathy were compared in a “blind” study with diabetic patients. The aim was to evaluate tests of tactile directional sensibility. Three matched groups were examined, two groups with type I diabetes,
Autor:
Mette Axelsen, Ulf Smith, Per-Anders Jansson, Björn Eliasson, Eugenia Carvalho, Christian Wesslau
Publikováno v:
Annals of the New York Academy of Sciences. 892:119-126
Adipose tissue only accounts for a relatively small proportion (< 10%) of the peripheral glucose utilization in response to insulin. However, the fat cells may still play an important role in insulin resistance and Syndrome X through, for instance, i
Publikováno v:
Journal of Internal Medicine. 245:229-236
The present study tests two interrelated hypotheses: (1) that bedtime ingestion of uncooked cornstarch exerts a lower and delayed nocturnal blood glucose peak compared with a conventional snack; (2) that bedtime carbohydrate supplement, administered
Autor:
Cristina M. Rondinone, Ulf Smith, Ling-Mei Wang, Jacalyn H. Pierce, Christian Wesslau, Peter Lönnroth
Publikováno v:
Proceedings of the National Academy of Sciences. 94:4171-4175
The large docking protein IRS-1 is a major substrate for the insulin receptor and other tyrosine kinases. It plays a key role in eliciting many of insulin’s actions, including binding and activation of phosphatidylinositol (PI) 3-kinase and the sub
Publikováno v:
Diabetologia. 39:235-242
Aqueous solutions of peroxovanadium (pV) compounds are potent insulin-mimics in various types of cell. Since chemical instability is a problem with these agents, we studied the insulin-like action in human fat cells of a stable pV complex, bpV(pic).
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1189:163-167
To assess the role of the cGMP-inhibitable phosphodiesterase (cGI-PDE) in the action of insulin on glucose transport, adipocytes from young, lean rats were preincubated for 20 min at 37 degrees C with and without OPC 3911, a specific inhibitor of cGI
Publikováno v:
Biochemical and Biophysical Research Communications. 196:287-293
Treating rats with pertussis toxin (PTX) both elevated the adipocyte cAMP levels and impaired sensitivity and responsiveness to the antilipolytic effect of insulin in the presence of different beta-adrenergic agonists. However, in the presence of a f
Publikováno v:
Diabetes. 41:1360-1365
A recent study by C.F. Burant et al. (13) demonstrates that GLUT5 is a high-affinity fructose transporter with a much lower capacity to transport glucose. To characterize the potential role of GLUT5 in fructose and glucose transport in insulin-sensit
Autor:
Christian Wesslau, Jan Borén, Olov Wiklund, Stig Attvall, Markku Laakso, Björn Eliasson, Ulf Smith
Publikováno v:
Journal of internal medicine. 260(5)
This publication is a summary of the presentations given at the First JIM Grand Round held at the Sahlgrenska University Hospital on 15 March 2006. The Grand Round was based on two case reports; a patient with type 2 diabetes and pronounced macrovasc