Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Christian Webhofer"'
Autor:
Hweixian Leong Penny, Kelly Hainline, Nathaniel Theoharis, Bin Wu, Christian Brandl, Christian Webhofer, Mason McComb, Sabine Wittemer-Rump, Gökben Koca, Sabine Stienen, Ralf C. Bargou, Horst-Dieter Hummel, Wolfgang Loidl, Carsten Grüllich, Tobias Eggert, Ben Tran, Daniel T. Mytych
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn oncology, anti-drug antibody (ADA) development that significantly curtails response durability has not historically risen to a level of concern. The relevance and attention ascribed to ADAs in oncology clinical studies have therefore b
Externí odkaz:
https://doaj.org/article/212fa5cf8e9f4350b4b25e8f215a32d7
Autor:
Christoph W. Turck, Christian Webhofer, Stefan Reckow, Jeffrey Moy, Mei Wang, Christelle Guillermier, J. Collin Poczatek, Michaela D. Filiou
A major challenge in managing depression is that antidepressant drugs take a long time to exert their therapeutic effects. For the development of faster acting therapies, it is crucial to get an improved understanding of the molecular mechanisms unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda84dc5dff972f229a98a6c03fcd55f
Variability assessment of 15N metabolic labeling-based proteomics workflow in mouse plasma and brain
Autor:
C. W. Turck, Giuseppina Maccarrone, Magdalena Soukupova, Michaela D. Filiou, Christian Webhofer, Christiane Rewerts
Publikováno v:
Molecular BioSystems. 11:1536-1542
(15)N metabolic labeling-based quantitative proteomics is used for the identification of disease- and phenotype-related alterations in live organisms. The variability of (15)N metabolic labeling proteomics workflows has been assessed in plants and ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd7061be002e96fcc3d9924340bb9fa
https://doi.org/10.1039/c4mb00702f
https://doi.org/10.1039/c4mb00702f
Autor:
Julie Howard, Marianne B. Müller, Frederik Dethloff, Kathryn S. Lilley, Michaela D. Filiou, Jamie Iannace, Christoph W. Turck, Christian Webhofer, Katja Weckmann, Larysa Teplytska, Giuseppina Maccarrone, Renata Feret, Christiana Labermaier, John M. Asara, Michael J. Deery
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
SCIENTIFIC REPORTS
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
SCIENTIFIC REPORTS
Fewer than 50% of all patients with major depressive disorder (MDD) treated with currently available antidepressants (ADs) show full remission. Moreover, about one third of the patients suffering from MDD does not respond to conventional ADs and deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77514616bb52dcf72ccddc3b1ecfaaa
https://pubmed.ncbi.nlm.nih.gov/29150633
https://pubmed.ncbi.nlm.nih.gov/29150633
Autor:
Chrysoula Dioli, Giuseppina Maccarrone, Michaela D. Filiou, Larysa Teplytska, M. Morais, Christoph W. Turck, Sofia Lopes, Nuno Sousa, Joao Vaz-Silva, Ioannis Sotiropoulos, Rita Trindade, Christian Webhofer, Osborne F. X. Almeida
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Tau protein in dendrites and synapses has been recently implicated in synaptic degeneration and neuronal malfunction. Chronic stress, awell-known inducer of neuronal/synaptic atrophy, triggers hyperphosphorylation of Tau protein and cognitive deficit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a64f80cc00c732aadce3f6234324f39
Autor:
Marianne B. Müller, Georg Jaschke, Christoph W. Turck, Alexander S. Häusl, Mathias V. Schmidt, D. Harbich, Gengjing Zhao, Theo Rein, Sara Santarelli, Marcel Schieven, Christiana Labermaier, Joseph G. Wettstein, Nils C. Gassen, Klaus V. Wagner, Xiao-Dong Wang, Bianca Schmid, Jakob Hartmann, Natalie Matosin, Christine Kohl, Lothar Lindemann, Christian Webhofer
Publikováno v:
Europe PubMed Central
Stress-induced psychiatric disorders, such as depression, have recently been linked to changes in glutamate transmission in the central nervous system. Glutamate signaling is mediated by a range of receptors, including metabotropic glutamate receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb16eac855e7eff73a6fd505315d6038
https://doi.org/10.1038/npp.2014.308
https://doi.org/10.1038/npp.2014.308
Autor:
Joao Vaz-Silva, Nuno Sousa, Chrysoula Dioli, Michaela D. Filiou, Larysa Teplytska, Christoph W. Turck, Ioannis Sotiropoulos, Christian Webhofer, Sofia Oliveira Lopes, Osborne F. X. Almeida, M. Morais
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01c136371c8409ff47ed6960232b2214
https://doi.org/10.1016/j.jalz.2016.06.619
https://doi.org/10.1016/j.jalz.2016.06.619
Autor:
Markus Nussbaumer, Michaela D. Filiou, Christoph W. Turck, Alon Chen, Larysa Teplytska, Christian Webhofer, Giuseppina Maccarrone
Publikováno v:
Proteomics. Clinical applications. 10(12)
Purpose In this work, we discuss how in vivo 15 N metabolic labeling in combination with MS simultaneously provides information on protein expression and protein turnover. Experimental design We metabolically labeled mice with the stable nitrogen iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b96a560228bdb53b1373052ae9541b
https://pubmed.ncbi.nlm.nih.gov/27763719
https://pubmed.ncbi.nlm.nih.gov/27763719
Autor:
Marcus Ising, Marianne B. Müller, Manfred Uhr, Carine Dournes, Nils C. Gassen, Michaela D. Filiou, John M. Asara, Christian Webhofer, Christoph W. Turck, Inge Sillaber, Theo Rein, Dong Ik Park
Publikováno v:
Scientific Reports
SCIENTIFIC REPORTS
SCIENTIFIC REPORTS
Selective Serotonin Reuptake Inhibitors (SSRIs) are commonly used drugs for the treatment of psychiatric diseases including major depressive disorder (MDD). For unknown reasons a substantial number of patients do not show any improvement during or af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a0d593ef07a686440e2788f9cd927f
https://pubmed.ncbi.nlm.nih.gov/27731396
https://pubmed.ncbi.nlm.nih.gov/27731396
Autor:
Michaela D. Filiou, Christoph W. Turck, Philipp Khaitovich, Christian Webhofer, Kathrin Henes, John M. Asara, Carsten T. Wotjak, Zhisong He, Chi-Ya Kao
Posttraumatic stress disorder (PTSD) is a prevalent psychiatric disorder. Several studies have attempted to characterize molecular alterations associated with PTSD, but most findings were limited to the investigation of specific cellular markers in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de751164b0cdb59dec792b7b03c0e569
https://europepmc.org/articles/PMC4996011/
https://europepmc.org/articles/PMC4996011/